scholarly journals Microcentrifuge Tubes as Disposable Immunoelectrochemical Cells for the On-Site Determination of GFAP, Biomarker of Hemorrhagic Stroke

Proceedings ◽  
2020 ◽  
Vol 60 (1) ◽  
pp. 10
Author(s):  
Andrea González-López ◽  
Estefanía Costa-Rama ◽  
Carmen García-Cabo Fernández ◽  
Lorena Benavente-Fernández ◽  
Sergio Calleja-Puerta ◽  
...  
Keyword(s):  
Stainless Steel ◽  
Acute Stroke ◽  
Hemorrhagic Stroke ◽  
Economic Benefits ◽  
Microcentrifuge Tube ◽  
Important Challenge ◽  
Capture Antibody ◽  
Analytical Tools ◽  
Neuroimaging Techniques

Stroke is the leading cause of mortality worldwide. Differentiating patients with intracerebral hemorrhage (ICH) or ischemic stroke in the first hours of symptoms onset is of paramount importance to the optimal management of patients. Current diagnosis of acute stroke relies on neuroimaging techniques that provide valuable information but not always are readily available. In this context, the development of analytical tools capable of a rapid and on-site differentiation between the types of stroke is an important challenge with great socio-economic benefits. Glial fibrillary acidic protein (GFAP) is considered one of the ICH biomarkers in patients with symptoms of acute stroke. In this work, a simple electroanalytical device for the analysis of GFAP was developed combining stainless-steel pins and a microcentrifuge tube. The sandwich immunoassay for the determination of GFAP was carried out inside the microcentrifuge tube immobilizing the capture antibody on the bottom of the tube. The three stainless-steel pins acting as electrodes were inserted in the cap in such a way that, when the immunoassay is finished, the tube is turned bottom up allowing the electrochemical detection in the same tube.

scholarly journals Development of safe optimized welding procedures for high strength Q&T steel welded with austenitic consumables

2013 ◽  
Vol 18 (2) ◽  
pp. 169-175 ◽  
Author(s):  
Lenka Kuzmikova ◽  
Huijun Li ◽  
John Norrish ◽  
Zengxi Pan ◽  
Nathan Larkin
Keyword(s):  
Stainless Steel ◽  
Austenitic Stainless Steel ◽  
High Strength ◽  
Economic Benefits ◽  
Cold Cracking ◽  
Ferritic Steels ◽  
Temperature Threshold ◽  
Safe Level ◽  
Interpass Temperature

High strength quenched and tempered (Q&T) steels offer obvious economic benefits originating from their advantageous strength to price and weight ratios. These steels are usually welded using ferritic consumables and for this combination the risk of hydrogen assisted cold cracking (HACC) is high. The use of austenitic stainless steel (ASS) consumables has great potential to significantly improve this issue. Yet, there are no guidelines for determination of safe level of preheat for welding ferritic steels with ASS consumables. For this reason manufacturers adopt this parameter from procedures developed for conventional ferritic consumables thus significantly limiting the benefits ASS consumables are capable to deliver. Productivity could be further enhanced by identifying the upper interpass temperature threshold, thus reducing the stand-off times. Aim of this work is to develop safe highly optimised procedures for welding of high strength Q&T steel with ASS consumable.

ANALYTICAL TOOLS AND MANAGEMENT METHOD OF CASH FLOWS AT THE ENTERPRISE

2017 ◽  
pp. 93-105
Author(s):  
Olha NIPIALIDI
Keyword(s):  
Financial Stability ◽  
Cash Flows ◽  
Sustainable Growth ◽  
Financial Health ◽  
Traditional Assessment ◽  
Financial Condition ◽  
Efficient Management ◽  
Expert Assessments ◽  
Analytical Tools

Introduction. The most important factors for “financial health” of the company are effectively structured cash flows, precondition for sustainable growth and achievement of high end results of economic activity as a whole. Knowledge and practical use of modern methods of organization and efficient management of cash flows enables transition of the company to a new quality of economic development. Purpose. The aim of the article is the research and development of theoretical, methodological and practical recommendations concerning the organization of the management process of cash flows at the enterprise. Results. Methodology of traditional assessment of financial stability of the enterprise, its elements and the factors influencing it can significantly complement and improve through the use of advanced mathematical models that allow to analyze the accuracy and objectivity of expert assessments for determination the level of the financial condition of the enterprise. Conclusion. The system of indicators used in the analysis of cash flows at the enterprises is investigated and systematized. It is advisable to choose those indicators from the total aggregate of indicators that are the most attracted to specific users of accounting information. Methods for analyzing cash flow is supplemented as regards the determination of the integral index of financial stability, which makes it possible to install ranked of the investigated enterprise. Proposals for amendments the methodological approaches to estimating of future cash flows will allow more effectively increase usefulness and reliability of accounting and analytical information for making management decisions.

scholarly journals Software Tools for Energy Storage Valuation and Design

2021 ◽  
Author(s):  
Tu A. Nguyen ◽  
Raymond H. Byrne
Keyword(s):  
Energy Storage ◽  
Storage Systems ◽  
System Simulation ◽  
Energy Systems ◽  
Software Tools ◽  
Economic Benefits ◽  
Design Tools ◽  
Power System Simulation ◽  
Analysis Tools ◽  
Analytical Tools

Abstract Purpose of Review As the application space for energy storage systems (ESS) grows, it is crucial to valuate the technical and economic benefits of ESS deployments. Since there are many analytical tools in this space, this paper provides a review of these tools to help the audience find the proper tools for their energy storage analyses. Recent Findings There are many software tools for valuating ESS. These tools can be classified into two groups: (1) power system simulation and planning tools for analyzing the technical contributions of ESSs, and (2) techno-economic analysis tools for valuating the economic benefits of ESS deployment and specifying the optimal design of energy systems that include ESSs. While many of the tools, developed by the national laboratories, are free to use, the commercial tools are also of great importance in meeting the customers’ specific needs. Summary This paper provides a review of software tools for ESS valuation and design. A review of analysis tools for evaluating the technical impacts of energy storage deployments is also provided, as well as a discussion of development trends for valuation and design tools.

scholarly journals Long-Term Influence of Laser-Processing Parameters on (Super)hydrophobicity Development and Stability of Stainless-Steel Surfaces

Materials ◽  
2018 ◽  
Vol 11 (11) ◽  
pp. 2240 ◽  
Author(s):  
Peter Gregorčič ◽  
Marjetka Conradi ◽  
Luka Hribar ◽  
Matej Hočevar
Keyword(s):  
Contact Angle ◽  
Stainless Steel ◽  
Processing Parameters ◽  
Nanosecond Laser ◽  
Stainless Steel Surface ◽  
Textured Surfaces ◽  
Laser Texturing ◽  
Important Challenge ◽  
Faster Development

Controlling the surface wettability represents an important challenge in the field of surface functionalization. Here, the wettability of a stainless-steel surface is modified by 30-ns pulses of a Nd:YAG marking laser (λ = 1064 nm) with peak fluences within the range 3.3–25.1 J cm−2. The short- (40 days), intermediate- (100 days) and long-term (1 year) superhydrophilic-to-(super)hydrophobic transition of the laser-textured surfaces exposed to the atmospheric air is examined by evaluating its wettability in the context of the following parameters: (i) pulse fluence; (ii) scan line separation; (iii) focal position and (iv) wetting period due to contact angle measurements. The results show that using solely a short-term evaluation can lead to wrong conclusions and that the faster development of the hydrophobicity immediately after laser texturing usually leads to lower final contact angle and vice versa, the slower this transition is, the more superhydrophobic the surface is expected to become (possibly even with self-cleaning ability). Depending on laser fluence, the laser-textured surfaces can develop stable or unstable hydrophobicity. Stable hydrophobicity is achieved, if the threshold fluence of 12 J cm−2 is exceeded. We show that by nanosecond-laser texturing a lotus-leaf-like surface with a contact angle above 150° and roll-off angle below 5° can be achieved.

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