scholarly journals Changes in the Selected Antioxidant Defense Parameters in the Blood of Patients after High Resolution Computed Tomography

2019 ◽  
Vol 16 (9) ◽  
pp. 1476 ◽  
Author(s):  
Amira Bryll ◽  
Wirginia Krzyściak ◽  
Anna Jurczak ◽  
Robert Chrzan ◽  
Anna Lizoń ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Computed Tomography ◽  
High Resolution ◽  
Ionizing Radiation ◽  
Antioxidant Defense ◽  
Antioxidant Systems ◽  
High Resolution Computed Tomography ◽  
Time Points ◽  
Antioxidant Markers

Ionizing radiation generated during high resolution computed tomography (HRCT) scanning may have an indirect effect on the mechanisms regulating the oxidative-antioxidant balance in the human body, which is one of the necessary factors ensuring the maintenance of its homeostasis. The aim of the study was to analyze the response of antioxidant systems through the determination of the antioxidant markers in the blood of patients exposed to oxidative stress resulting from the routine HRCT examination of the chest. Blood of 35 people aged 60.77 ± 10.81 taken before and at four time points after the examination constituted the test material. The determination of the total antioxidant capacity expressed as ferric reducing ability of plasma (FRAP) and ferric reducing antioxidant activity and ascorbic acid concentration (FRASC) were performed together with an examination of catalase activity and the concentration of the reduced glutathione. The organism’s response to ionizing radiation was associated with a significant decrease in the antioxidant markers’ levels at all time-points and showed a significant negative correlation depending on the radiation dose. Visible down-regulation of these markers is a response to increased oxidative stress. In light of the obtained results, the measurement of the selected markers of antioxidant defense may be a useful parameter of oxidative stress caused by ionizing radiation.

Determination of the Activity of Pulmonary Tuberculosis: the Utility of High-Resolution Computed Tomography

2000 ◽  
Vol 42 (5) ◽  
pp. 757
Author(s):  
Myung Hee Chung ◽  
Hae Giu Lee ◽  
Won Jong Yu ◽  
Hong Jun Chung ◽  
Bo Sung Yang ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Pulmonary Tuberculosis ◽  
High Resolution Computed Tomography

Acute Pulmonary Oxygen Toxicity in Rats: Findings and Lung Density Changes in High Resolution Computed Tomography

2000 ◽  
Vol 42 (3) ◽  
pp. 473
Author(s):  
Dae Sik Ryu ◽  
Kun Sang Kim ◽  
Kil Hyen Kang ◽  
Haing Sup Chung ◽  
Bung Wok Lee ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Oxygen Toxicity ◽  
High Resolution Computed Tomography ◽  
Lung Density

Bone marrow densitometry by clinical high resolution computed tomography of human vertebrae

2014 ◽  
Author(s):  
Jaime Pena ◽  
Graeme Campbell ◽  
Timo Damm ◽  
Reinhard Barkmann ◽  
Sonja Waldhausen ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bone Marrow ◽  
High Resolution ◽  
High Resolution Computed Tomography

Computed tomography in diagnosis of silicosis

2019 ◽  
pp. 39-41
Author(s):  
Alina S. Kovaleva ◽  
Igor V. Bukhtiyarov ◽  
Natalya S. Serova ◽  
Tatyana B. Burmistrova
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Respiratory System ◽  
Evidence Based Medicine ◽  
Occupational Disease ◽  
Occupational Medicine ◽  
Occupational Diseases ◽  
Evidence Based ◽  
High Resolution Computed Tomography ◽  
Based Medicine

Respiratory system diseases are one of the main problems in contemporary occupational medicine and exceed one fifth of all occupational diseases. Objective of the review was search and analysis of literature on diagnosis of silicosis as an important occupational disease of respiratory organs, by computed tomography and high-resolution computed tomography, from evidence-based medicine viewpoint.

High Resolution Computed Tomography of Auditory Ossicles

1990 ◽  
Vol 31 (1) ◽  
pp. 27-31
Author(s):  
M. Isono ◽  
K. Murata ◽  
F. Ohta ◽  
A. Yoshida ◽  
O. Ishida
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
High Resolution Computed Tomography ◽  
Auditory Ossicles

scholarly journals AB0605 CLINICAL PROFILE AND CHEST HIGH-RESOLUTION COMPUTED TOMOGRAPHY (HRCT) FINDINGS IN PATIENTS WITH CONNECTIVE TISSUE DISEASES AND INTERSTITIAL LUNG DISEASE: EXPERIENCE OF A SINGLE REFERENCE RHEUMATOLOGY CENTER

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1598.2-1599
Author(s):  
I. Rusu ◽  
L. Muntean ◽  
M. M. Tamas ◽  
I. Felea ◽  
L. Damian ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Systemic Sclerosis ◽  
High Resolution ◽  
Interstitial Lung Disease ◽  
Connective Tissue ◽  
Lung Disease ◽  
Interstitial Pneumonia ◽  
Connective Tissue Diseases ◽  
High Resolution Computed Tomography ◽  
Hrct Patterns

Background:Interstitial lung disease (ILD) is a common manifestation of connective tissue diseases (CTDs), and is associated with significant morbidity and mortality. Chest high-resolution computed tomography (HRCT) play an important role in the diagnosis of ILD and may provide prognostic information.Objectives:We aimed to characterize the clinical profile and chest HRCT abnormalities and patterns of patients diagnosed with CTDs and ILD.Methods:In this retrospective, observational study we included 80 consecutive patients with CTDs and ILD referred to a tertiary rheumatology center between 2015 and 2019. From hospital charts we collected clinical data, immunologic profile, chest HRCT findings. HRCT patterns were defined according to new international recommendations.Results:Out of 80 patients, 64 (80%) were women, with a mean age of 55 years old. The most common CTD associated with ILD was systemic sclerosis (38.8%), followed by polymyositis (22.5%) and rheumatoid arthritis (18.8%). The majority of patients had dyspnea on exertion (71.3%), bibasilar inspiratory crackles were present in 56.3% patients and 10% had clubbing fingers. Antinuclear antibodies (ANA) were present in 78.8% patients, and the most frequently detected autoantibodies against extractable nuclear antigen were anti-Scl 70 (28.8%), followed by anti-SSA (anti-Ro, 17.5%), anti-Ro52 (11.3%) and anti-Jo (7.5%). Intravenous cyclophosphamide therapy for 6-12 months was used in 35% of patients, while 5% of patients were treated with mycophenolate mofetil.The most frequent HRCT abnormalities were reticular abnormalities and ground glass opacity. Non-specific interstitial pneumonia (NSIP) was identified in 46.3% CTDs patients. A pattern suggestive of usual interstitial pneumonia (UIP) was present in 32.5% patients, mainly in patients with systemic sclerosis. In 21.3% patients the HRCT showed reticulo-nodular pattern, micronodules and other abnormalities, not diagnostic for UIP or NSIP pattern.Conclusion:Nonspecific interstitial pneumonia (NSIP) is the most common HRCT pattern associated with CTDs. Further prospective longitudinal studies are needed in order to determine the clinical and prognostic significance of various HRCT patterns encountered in CTD-associated ILD and for better patient management.References:[1]Ohno Y, Koyama H, Yoshikaua T, Seki S. State-of-the-Art Imaging of the Lung for Connective Tissue Disease (CTD). Curr Rheumatol Rep. 2015;17(12):69.[2]Walsh SLF, Devaraj A, Enghelmeyer JI, Kishi K, Silva RS, Patel N, et al. Role of imaging in progressive-fibrosing interstitial lung diseases. Eur Respir Rev. 2018;27(150)Disclosure of Interests:None declared

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