scholarly journals Effects of Regular Aerobic Exercise and Resistance Training on High-Density Lipoprotein Cholesterol Levels in Taiwanese Adults

2019 ◽  
Vol 16 (11) ◽  
pp. 2003 ◽  
Author(s):  
Chun-Sheng Hsu ◽  
Shin-Tsu Chang ◽  
Oswald Ndi Nfor ◽  
Kuan-Jung Lee ◽  
Shiuan-Shinn Lee ◽  
...  
Keyword(s):  
Resistance Training ◽  
High Density Lipoprotein ◽  
Aerobic Exercise ◽  
High Density Lipoprotein Cholesterol ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Research Database ◽  
Cardiovascular Risks ◽  
Positive Effects

Increased levels of high-density lipoprotein cholesterol (HDL-C) can improve endothelial function. This may help reduce cardiovascular risks and mortality. Evidence has been provided on the association between cardiometabolic traits, such as HDL-C and exercise modalities. However, there is the absence of studies investigating this association in Taiwan. We assessed the relationship between exercise type and HDL-C among Taiwanese adults. Data were collected from Taiwan Biobank (TWB), a national biomedical research database that contains the genetic information of ethnic Taiwanese residents gathered from 2008 to 2016. We enrolled 24,856 participants aged 30 to 70 years who completed a questionnaire about their recent health behaviors including smoking, drinking, and exercise. Regular exercise was categorized as non-aerobic exercise (separated as weight training, ball game, and mixed exercise) and strict aerobic exercise. Linear regression models were used to assess the effects of exercise in a questionnaire-based manner. After multivariate adjustments, HDL-C was positively associated with aerobic (β = 1.33748, p < 0.0001) and non-aerobic (β = 2.56210; p < 0.0001) exercise. Positive associations were also found for resistance training (β = 4.01828, p = 0.0020), ballgame (β = 2.43815, p = 0.0001), and mixed exercise (β = 2.47021, p < 0.0001). This study demonstrated that both aerobic and non-aerobic exercise have positive effects on HDL-C among Taiwanese adults. Among the non-aerobic exercise groups, resistance training had the greatest effect.

scholarly journals APOE genotype affects black-white responses of high-density lipoprotein cholesterol subspecies to aerobic exercise training

Metabolism ◽  
2008 ◽  
Vol 57 (12) ◽  
pp. 1669-1676 ◽  
Author(s):  
Thomas O. Obisesan ◽  
Robert E. Ferrell ◽  
Andrew P. Goldberg ◽  
Dana A. Phares ◽  
Tina J. Ellis ◽  
...  
Keyword(s):  
Exercise Training ◽  
High Density Lipoprotein ◽  
Aerobic Exercise ◽  
High Density Lipoprotein Cholesterol ◽  
Apoe Genotype ◽  
Density Lipoprotein ◽  
High Density ◽  
Aerobic Exercise Training ◽  
Lipoprotein Cholesterol

Abstract TP198: Combined Diet and Aerobic Exercise Reduces non-HDL-C in Adults: A Meta-Analysis of Randomized Controlled Trials

Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
George A Kelley ◽  
Kristi S Kelley
Keyword(s):  
High Density Lipoprotein ◽  
Aerobic Exercise ◽  
Randomized Controlled Trials ◽  
High Density Lipoprotein Cholesterol ◽  
Statistical Significance ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Controlled Trials ◽  
Randomized Controlled

BACKGROUND AND PURPOSE: Non-high-density lipoprotein cholesterol (non-HDL-C) is associated with an increased risk for cerebrovascular disease. However, the effects of three community-deliverable lifestyle interventions [diet (D), aerobic exercise (E), or both (DE)] on non-HDL-C in adults are not known. The purpose of this study was to use the aggregate data meta-analytic approach to address this gap. METHODS: A priori study eligibility included randomized controlled trials >4 weeks that included a D, E, DE and control (C) group in adults >18 years of age in which data for total cholesterol (TC) and high-density lipoprotein cholesterol (HDL-C) were available for calculating non-HDL-C. Studies were retrieved by searching nine electronic databases, cross-referencing and expert review. Dual data selection and extraction were conducted. A mixed effects model was employed whereby a random-effects approach was used to combine effect size (ES) results within each subgroup while a fixed-effect approach was used to compare subgroups (Q b ). Heterogeneity was examined using the Q and I 2 statistics and 95% confidence intervals (CI) were also calculated. Statistical significance was set at p < 0.05 while a trend for statistical significance was set between p >0.05 to < 0.10. RESULTS: Overall, a statistically significant exercise minus control group decrease in non-HDL-C was found for DE (7 ESs, 389 participants, mean, -11.1 mg/dl, 95% CI, -21.7 to -0.6, p =0.04, Q=2.4, p =0.88, I 2 =0%), a trend for the D group (7 ESs, 402 participants, mean, -8.5 mg/dl, 95% CI, -18.6 to 1.6, p =0.10, Q=0.76, p =0.99, I 2 =0%) and no change for the E group (7 ESs, 387 participants, mean, 3.0 mg/dl, 95% CI, -7.1 to 13.1, p =0.56, Q=0.78, p =0.99, I 2 =0%). Relative changes were -6.5%, -5.6%, and 0.8% respectively, for DE, D and E groups. Overall, no statistically significant between-group differences were found (Q b = 4.1, p = 0.12). There was a trend for decreases in non-HDL-C to be greater in the DE versus E group (Q b = 3.6, p = 0.06) with no statistically significant differences between D and E (Q b = 2.5, p = 0.12) or DE and D (Q b = 0.1, p = 0.72) groups. CONCLUSIONS: Combined DE reduces non-HDL-C in adults.

Association between the nonHDLc/HDLc ratio and 30-day mortality for patients with sepsis: a retrospective observational cohort study based on a large multicentre critical care database

2021 ◽  
Author(s):  
Le Chang ◽  
Xinglin Chen ◽  
Zhengxu Ye
Keyword(s):  
High Density Lipoprotein ◽  
High Density Lipoprotein Cholesterol ◽  
Turning Point ◽  
Density Lipoprotein ◽  
The United States ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Research Database ◽  
Multivariable Logistic Regression Model ◽  
Using Data

Abstract Background: Dyslipidemia contributes to the development and progression of cardiovascular disease. The objective of this study was to investigate the association between the non-high-density lipoprotein-cholesterol-to-high-density lipoprotein-cholesterol (non-HDL-c/HDL-c) ratio and mortality for patients with sepsis.Methods: Using data from the eICU Collaborative Research Database (eICU-CRD) with high granularity data for over 200,000 admissions to ICUs monitored by eICU Programs across the United States. We identified 1680 patients with sepsis. All-cause mortality within 30-days after the date of visit to the ICU. We estimated the risk of mortality using multivariable logistic-regression model.Result: There were 115 deaths (6.85%). The probability of mortality decreased when the nonHDLc/HDLc ratio lower than the turning point ( <3.58) with a adjusted odds ratio (OR) of 0.75 (95% CI: 0.61–0.94, P=0.011) for every 1 increment of nonHDLc/HDLc ratio. With the per-SD increase in the nonHDLc/HDLc ratio, the OR for mortality was 0.36 (95% CI: 0.16–0.79, P=0.011) when nonHDLc/HDLc ratio was <3.58, while the OR was 1.56 (95% CI: 1.29–1.88, P<0.001) when nonHDLc/HDLc ratio was ≥ 3.58.Conclusion: Higher nonHDLc/HDLc ratio, even at a low level, was associated with a higher risk of 30-day mortality for patients with sepsis. The probability of mortality rose rapidly when the nonHDLc/HDLc ratio higher than the turning point (may at 3.58).

Triglyceride to high density lipoprotein cholesterol ratio, total cholesterol to high density lipoprotein cholesterol ratio and low ankle brachial index in an elderly population

VASA ◽  
2014 ◽  
Vol 43 (3) ◽  
pp. 189-197 ◽  
Author(s):  
Yiqiang Zhan ◽  
Jinming Yu ◽  
Rongjing Ding ◽  
Yihong Sun ◽  
Dayi Hu
Keyword(s):  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
High Density Lipoprotein Cholesterol ◽  
Ankle Brachial Index ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Lipid Lowering ◽  
Cholesterol Ratio ◽  
Potential Biomarker

Background: The associations of triglyceride (TG) to high-density lipoprotein cholesterol ratio (HDL‑C) and total cholesterol (TC) to HDL‑C ratio and low ankle brachial index (ABI) were seldom investigated. Patients and methods: A population based cross-sectional survey was conducted and 2982 participants 60 years and over were recruited. TG, TC, HDL‑C, and low-density lipoprotein cholesterol (LDL-C) were assessed in all participants. Low ABI was defined as ABI ≤ 0.9 in either leg. Multiple logistic regression models were applied to study the association between TG/HDL‑C ratio, TC/HDL‑C ratio and low ABI. Results: The TG/HDL‑C ratios for those with ABI > 0.9 and ABI ≤ 0.9 were 1.28 ± 1.20 and 1.48 ± 1.13 (P < 0.0001), while the TC/HDL‑C ratios were 3.96 ± 1.09 and 4.32 ± 1.15 (P < 0.0001), respectively. After adjusting for age, gender, body mass index, obesity, current drinking, physical activity, hypertension, diabetes, lipid-lowering drugs, and cardiovascular disease history, the odds ratios (ORs) with 95 % confidence intervals (CIs) of low ABI for TG/HDL‑C ratio and TC/HDL‑C ratio were 1.10 (0.96, 1.26) and 1.34 (1.14, 1.59) in non-smokers. When TC was further adjusted, the ORs (95 % CIs) were 1.40 (0.79, 2.52) and 1.53 (1.21, 1.93) for TG/HDL‑C ratio and TC/HDL‑C ratio, respectively. Non-linear relationships were detected between TG/HDL‑C ratio and TC/HDL‑C ratio and low ABI in both smokers and non-smokers. Conclusions: TC/HDL‑C ratio was significantly associated with low ABI in non-smokers and the association was independent of TC, TG, HDL‑C, and LDL-C. TC/HDL‑C might be considered as a potential biomarker for early peripheral arterial disease screening.

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