scholarly journals Recent Advances in Nanoparticle-Mediated Delivery of Anti-Inflammatory Phytocompounds

2017 ◽  
Vol 18 (4) ◽  
pp. 709 ◽  
Author(s):  
Raffaele Conte ◽  
Valentina Marturano ◽  
Gianfranco Peluso ◽  
Anna Calarco ◽  
Pierfrancesco Cerruti
Keyword(s):  
Recent Advances ◽  
Anti Inflammatory

scholarly journals Recent Advances: The Imbalance of Cytokines in the Pathogenesis of Inflammatory Bowel Disease

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
Qingdong Guan ◽  
Jiguo Zhang
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Inflammatory Cytokines ◽  
Bowel Disease ◽  
Intestinal Inflammation ◽  
Beneficial Effects ◽  
Recent Advances ◽  
Inflammatory Bowel ◽  
Inflammation Targeting ◽  
Anti Inflammatory

Cytokines play an important role in the immunopathogenesis of inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis, where they drive and regulate multiple aspects of intestinal inflammation. The imbalance between proinflammatory and anti-inflammatory cytokines that occurs in IBD results in disease progression and tissue damage and limits the resolution of inflammation. Targeting cytokines have been novel strategies in the treatment of IBD. Recent studies show the beneficial effects of anticytokine treatments to IBD patients, and multiple novel cytokines are found to be involved in the pathogenesis of IBD. In this review, we will discuss the recent advances of novel biologics in clinics and clinical trials, and novel proinflammatory and anti-inflammatory cytokines found in IBD with focusing on IL-12 family and IL-1 family members as well as their relevance to the potential therapy of IBD.

scholarly journals Recent Advances in Nonsteroidal Anti-Inflammatory Drugs

2005 ◽  
Vol 54 (2) ◽  
pp. 209-215 ◽  
Author(s):  
Shinichi Kawai ◽  
Fumiaki Kojima ◽  
Natsuko Kusunoki
Keyword(s):  
Recent Advances ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Recent Advances in Anti-inflammatory Potential of Pyridazinone Derivatives

2016 ◽  
Vol 16 (12) ◽  
pp. 996-1012 ◽  
Author(s):  
Minaxi Saini ◽  
Dinesh Kumar Mehta ◽  
Rina Das ◽  
Gurnam Saini
Keyword(s):  
Recent Advances ◽  
Anti Inflammatory ◽  
Pyridazinone Derivatives

scholarly journals Recent Advances in the Pharmacological Activities of Dioscin

2019 ◽  
Vol 2019 ◽  
pp. 1-13 ◽  
Author(s):  
Longfei Yang ◽  
Shengnan Ren ◽  
Fei Xu ◽  
Zhiming Ma ◽  
Xin Liu ◽  
...  
Keyword(s):  
Pharmacological Activities ◽  
Protective Properties ◽  
The Past ◽  
Recent Advances ◽  
Clinical Disorders ◽  
Anti Inflammatory ◽  
Potential Use

Dioscin is a typical saponin with multiple pharmacological activities. The past few years have seen an emerging interest in and growing research on this pleiotropic saponin. Here, we review the emerging pharmacological activities reported recently, with foci on its antitumor, antimicrobial, anti-inflammatory, antioxidative, and tissue-protective properties. The potential use of dioscin in therapies of diverse clinical disorders is also discussed.

scholarly journals Recent Advances in the Semisynthesis, Modifications and Biological Activities of Ocotillol-Type Triterpenoids

Molecules ◽  
2020 ◽  
Vol 25 (23) ◽  
pp. 5562
Author(s):  
Yucheng Cao ◽  
Kaiyi Wang ◽  
Si Xu ◽  
Lingtan Kong ◽  
Yi Bi ◽  
...  
Keyword(s):  
Biological Activities ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Pharmacological Activities ◽  
Structure Activity ◽  
Recent Advances ◽  
The World ◽  
Anti Inflammatory ◽  
Active Substances

Ginseng is one of the most widely consumed herbs in the world and plays an important role in counteracting fatigue and alleviating stress. The main active substances of ginseng are its ginsenosides. Ocotillol-type triterpenoid is a remarkably effective ginsenoside from Vietnamese ginseng that has received attention because of its potential antibacterial, anticancer and anti-inflammatory properties, among others. The semisynthesis, modification and biological activities of ocotillol-type compounds have been extensively studied in recent years. The aim of this review is to summarize semisynthesis, modification and pharmacological activities of ocotillol-type compounds. The structure–activity relationship studies of these compounds were reported. This summary should prove useful information for drug exploration of ocotillol-type derivatives.

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