scholarly journals In Situ Hydroxyapatite Synthesis Enhances Biocompatibility of PVA/HA Hydrogels

2021 ◽  
Vol 22 (17) ◽  
pp. 9335
Author(s):  
Petra Chocholata ◽  
Vlastimil Kulda ◽  
Jana Dvorakova ◽  
Monika Supova ◽  
Margit Zaloudkova ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Organic Matrix ◽  
In Situ Synthesis ◽  
Human Osteoblast ◽  
Natural Behavior ◽  
Initial Adhesion ◽  
Hard Tissues ◽  
Physical Mixing

Bone tissue engineering tries to simulate natural behavior of hard tissues. This study aimed to produce scaffolds based on polyvinyl alcohol (PVA) and hyaluronic acid (HA) with hydroxyapatite (HAp) incorporated in two different ways, by in situ synthesis and physical mixing of pre-prepared HAp. In situ synthesis resulted in calcium deficient form of HAp with lower crystallinity. The proliferation of human osteoblast-like cells MG-63 proved to be better in the scaffolds with in situ synthesized HAp compared to those with physically mixed pre-prepared HAp. For scaffolds with PVA/HA/HAp ratio 3:1:2, there was significantly higher initial adhesion (p = 0.0440), as well as the proliferation in the following days (p < 0.001). It seemed to be advantageous improve the properties of the scaffold by in situ synthesizing of HAp directly in the organic matrix.

scholarly journals Highly porous PHB-based bioactive scaffolds for bone tissue engineering by in situ synthesis of hydroxyapatite

2019 ◽  
Vol 100 ◽  
pp. 286-296 ◽  
Author(s):  
Micaela Degli Esposti ◽  
Federica Chiellini ◽  
Federica Bondioli ◽  
Davide Morselli ◽  
Paola Fabbri
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
In Situ Synthesis ◽  
Bioactive Scaffolds ◽  
Highly Porous

In situ synthesis of luminescent carbon nanoparticles toward target bioimaging

Nanoscale ◽  
2015 ◽  
Vol 7 (12) ◽  
pp. 5468-5475 ◽  
Author(s):  
Shazid Md. Sharker ◽  
Sung Min Kim ◽  
Jung Eun Lee ◽  
Ji Hoon Jeong ◽  
Insik In ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Carbon Nanoparticles ◽  
In Situ Synthesis

In situ synthesis of fluorescence carbon nanoparticles (FCNs) for target bioimaging applications derived from biocompatible hyaluronic acid (HA) without conjugation.

Fully defined in situ cross-linkable alginate and hyaluronic acid hydrogels for myocardial tissue engineering

Biomaterials ◽  
2013 ◽  
Vol 34 (4) ◽  
pp. 940-951 ◽  
Author(s):  
Julia Dahlmann ◽  
Andreas Krause ◽  
Lena Möller ◽  
George Kensah ◽  
Markus Möwes ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Myocardial Tissue ◽  
Myocardial Tissue Engineering

In situ cross-linkable hyaluronic acid hydrogels using copper free click chemistry for cartilage tissue engineering

2018 ◽  
Vol 9 (1) ◽  
pp. 20-27 ◽  
Author(s):  
Sang-Soo Han ◽  
Hong Yeol Yoon ◽  
Ji Young Yhee ◽  
Myeong Ok Cho ◽  
Hye-Eun Shim ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Hyaluronic Acid ◽  
Click Chemistry ◽  
Click Reaction ◽  
Cartilage Tissue Engineering ◽  
Cartilage Tissue

We develop a biocompatible and in situ HA hydrogel via a bioorthogonal click reaction for cartilage tissue engineering.

In situ synthesis of nano-sized cobalt ferrite particle/organic hybrid

2006 ◽  
Vol 21 (5) ◽  
pp. 1336-1341 ◽  
Author(s):  
Satoshi Nakamura ◽  
Wataru Sakamoto ◽  
Toshinobu Yogo
Keyword(s):  
Saturation Magnetization ◽  
Room Temperature ◽  
Cobalt Ferrite ◽  
Organic Matrix ◽  
In Situ Synthesis ◽  
Organic Hybrid ◽  
Ferrite Particle ◽  
Hydrolysis Conditions ◽  
Cobalt Acetylacetonate

A CoFe2O4 particle/organic hybrid was synthesized using in situ processing of metalorganics of cobalt and iron below 100 °C. A mixture of cobalt (II) acetylacetonate (CA) and iron (III) 3-allylacetylacetonate (IAA) was hydrolyzed and polymerized yielding cobalt ferrite particle/organic hybrid. The crystallinity of cobalt ferrite depended upon the hydrolysis conditions of cobalt acetylacetonate-iron 3-allylacetylacetonate (CA-IAA). Nanocrystalline cobalt ferrite particles were uniformly dispersed in the organic matrix. The saturation magnetization of hybrid increased with increasing crystallinity of cobalt ferrite particles in the organic matrix. The hybrid showed a magnetization-applied field (BH) curve with no coercive force at room temperature. The magnetization versus H/T curves from 150 to 300 K were superimposed on the same curve and satisfied the Langevin equation. The hybrid revealed a saturation magnetization of 33.7 emu/g and a coercivity of 11 kOe at 4.2 K.

Sign in / Sign up

Export Citation Format

Share Document