scholarly journals Levels of Produced Antibodies after Vaccination with mRNA Vaccine; Effect of Previous Infection with SARS-CoV-2

2021 ◽  
Vol 10 (13) ◽  
pp. 2842
Author(s):  
Theocharis G. Konstantinidis ◽  
Stavroula Zisaki ◽  
Ioannis Mitroulis ◽  
Eleni Konstantinidou ◽  
Eftychia G. Kontekaki ◽  
...  
Keyword(s):  
Quantitative Assay ◽  
Previous Infection ◽  
Immunogenic Response ◽  
Vaccine Effect

The aim of this study was to estimate the immunogenic effect of mRNA vaccine against SARS-CoV-2. This study included 510 participants who received mRNA vaccine. The measurement of anti-COVID-19 antibodies was performed using the Abbott SARS-CoV-2 IgG quantitative assay (Abbott). Overall, mean titer of anti-Spike antibodies was 19,319.2 ± 1787.5 AU/mL. Vaccination induced a robust immunogenic response in those previously infected with SARS-CoV-2 compared with non-infected subjects. Additionally, individuals that were asymptomatic after vaccination produced lower levels of antibodies compared to feverish individuals. In conclusion, remarkably high levels of anti-Spike COVID-19 antibodies were observed after vaccination.

scholarly journals Levels of produced antibodies after vaccination with mRNA vaccine; effect of previous infection with SARS-CoV-2

2021 ◽  
Author(s):  
Theocharis Konstantinidis ◽  
Stavroula Zisaki ◽  
Ioannis Mitroulis ◽  
Eleni Konstantinidou ◽  
Eftychia G. Kontekaki ◽  
...  
Keyword(s):  
Quantitative Assay ◽  
Previous Infection ◽  
High Level ◽  
Immunogenic Response ◽  
Vaccine Effect

AbstractThe aim of this study was to estimate the immunogenic effect of mRNA vaccine against SARS-CoV-2. This study included 510 participants who received mRNA vaccine. The measurement of anti-Covid-19 antibodies was performed using the Abbott SARS-CoV-2 IgG quantitative assay (Abbott). Overall, mean title of anti-Spike antibodies was 19319.2±1787.5 AU/ml. Vaccination induced a robust immunogenic response in previous infected with SARS-CoV-2 compared. Additionally, individuals that were asymptomatic after vaccination produced lower levels of antibodies compared to feverish individuals. In conclusion, remarkable high level of anti-Spike Covid-19 antibodies was found after vaccination.

Plasma Factor XIII and Platelet Factor XIII in Hyperlipaemia

1976 ◽  
Vol 36 (03) ◽  
pp. 542-550 ◽  
Author(s):  
Mircea P. Cucuianu ◽  
K Miloszewski ◽  
D Porutiu ◽  
M. S Losowsky
Keyword(s):  
Factor Xiii ◽  
Significant Contribution ◽  
Quantitative Assay ◽  
Factor Xii ◽  
Platelet Factor ◽  
Type Iv ◽  
Plasma Factor ◽  
Hepatic Synthesis

SummaryPlasma factor XIII activity measured by a quantitative assay was found to be significantly higher in hypertriglyceridaemic patients (type IV and combined hyperlipoproteinaemia), as compared to normolipaemic controls. No such elevation in plasma factor XIII activity was found in patients with type IIa hyperlipaemia. Plasma pseudocholinesterase was found to parallel the elevated factor XIII activity in hypertriglyceridaemic subjects.In contrast, platelet factor XIII activity was not raised in hyperlipaemic subjects, and plasma factor XIII was found to be normal in a normolipaemic subject with throm-bocythaemia.It was concluded that there is no significant contribution from platelets to plasma factor XIII activity, and that the observed increase in plasma factor XII in hypertriglyceridaemia results from enhanced hepatic synthesis of the enzyme.

Arthritis in children as a result of a previous infection caused by Yersinia enterocolitica and Yersinia pseudotuberculosis

2008 ◽  
Vol 63 (2) ◽  
pp. 88-92
Author(s):  
Michał Szczyrek ◽  
Anna Mełges ◽  
Alina Olender ◽  
Konrad Jarząbek ◽  
Jacek Postępski
Keyword(s):  
Yersinia Enterocolitica ◽  
Yersinia Pseudotuberculosis ◽  
Previous Infection

The Effect of Bleeding versus Previous Infection on the Resistance of Lambs to Subsequent Infections of Haemonchus Contortus

1958 ◽  
Vol 17 (2) ◽  
pp. 363-367 ◽  
Author(s):  
W. J. Bemrick ◽  
R. J. Emerick ◽  
R. F. Shumard ◽  
A. L. Pope ◽  
P. H. Phillips
Keyword(s):  
Haemonchus Contortus ◽  
Previous Infection

scholarly journals SARS-CoV-2 infection is at herd immunity in the majority segment of the population of Qatar

2021 ◽  
Author(s):  
Mohamed H Al-Thani ◽  
Elmoubasher Farag ◽  
Roberto Bertollini ◽  
Hamad Eid Al Romaihi ◽  
Sami Abdeen ◽  
...  
Keyword(s):  
Total Population ◽  
Herd Immunity ◽  
Geographic Location ◽  
Population Based ◽  
Infection Prevalence ◽  
Cross Sectional ◽  
Previous Infection ◽  
Current Infection ◽  
Polymerase Chain ◽  
Population Based Survey

Abstract Background Qatar experienced a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic that disproportionately affected the craft and manual worker (CMW) population who comprise 60% of the total population. This study aimed to assess ever and/or current infection prevalence in this population. Methods A cross-sectional population-based survey was conducted during July 26-September 09, 2020 to assess both anti-SARS-CoV-2 positivity through serological testing and current infection positivity through polymerase chain reaction (PCR) testing. Associations with antibody and PCR positivity were identified through regression analyses. Results Study included 2,641 participants, 69.3% of whom were <40 years of age. Anti-SARS-CoV-2 positivity was 55.3% (95% CI: 53.3-57.3%) and was significantly associated with nationality, geographic location, educational attainment, occupation, and previous infection diagnosis. PCR positivity was 11.3% (95% CI: 9.9-12.8%) and was significantly associated with nationality, geographic location, occupation, contact with an infected person, and reporting two or more symptoms. Infection positivity (antibody and/or PCR positive) was 60.6% (95% CI: 58.6-62.5%). The proportion of antibody-positive CMWs that had a prior SARS-CoV-2 diagnosis was 9.3% (95% CI: 7.9-11.0%). Only seven infections were ever severe and one was ever critical—an infection severity rate of 0.5% (95% CI: 0.2-1.0%). Conclusions Six in every 10 CMWs have been infected, suggestive of reaching the herd immunity threshold. Infection severity was low with only one in every 200 infections progressing to be severe or critical. Only one in every 10 infections had been previously diagnosed suggestive of mostly asymptomatic or mild infections.

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