scholarly journals Influence of Overhanging Bleb on Corneal Higher-Order Aberrations after Trabeculectomy

2021 ◽  
Vol 11 (1) ◽  
pp. 177
Author(s):  
Yu Mizuno ◽  
Kazuyuki Hirooka ◽  
Yoshiaki Kiuchi
Keyword(s):  
Mitomycin C ◽  
Pupil Diameter ◽  
Glaucoma Surgery ◽  
Higher Order ◽  
Control Group ◽  
Higher Order Aberrations ◽  
Ocular Surgery ◽  
Conjunctival Flap ◽  
Single Center Study ◽  
History Of

Recent advances in ocular aberrometry have revealed that ocular surgery increases ocular and corneal higher-order aberrations. This retrospective single-center study aimed to examine the effects of the overhanging bleb on corneal higher-order aberrations using a wavefront analyzer. We included 61 eyes from 50 patients with overhanging bleb after trabeculectomy with a fornix-based conjunctival flap using mitomycin C (overhanging bleb group) and 65 eyes from 54 glaucoma patients with no history of glaucoma surgery (control group). Corneal higher-order aberrations (total higher-order aberrations, coma aberrations, coma-like aberrations, spherical aberrations, and spherical-like aberrations) on a 4 mm pupil diameter were measured using the TOPCON KR-1W wavefront analyzer. Corneal coma aberrations were higher in the overhanging bleb group than in the control group (0.16 ± 0.13 μm and 0.10 ± 0.05 μm, respectively; p = 0.042). Corneal coma-like aberrations were also higher in the overhanging bleb group than in the control group (0.31 ± 0.32 μm and 0.16 ± 0.09 μm, respectively; p = 0.022). With an increasing ratio of cornea covered by the bleb to the entire cornea, all corneal higher-order aberrations increased except for corneal coma-like aberrations. Overhanging bleb after trabeculectomy with a fornix-based conjunctival flap using mitomycin C and its size influenced corneal higher-order aberrations.

scholarly journals Improvements in Optical Characteristics after Excision of an Overhanging Bleb Developed following Trabeculectomy

2021 ◽  
Vol 2021 ◽  
pp. 1-5
Author(s):  
Yu Mizuno ◽  
Atsushi Hirota ◽  
Kazuyuki Hirooka ◽  
Yoshiaki Kiuchi
Keyword(s):  
Visual Acuity ◽  
Pupil Diameter ◽  
Higher Order ◽  
Higher Order Aberrations ◽  
Case Presentation ◽  
Conjunctival Flap ◽  
Corrected Visual Acuity ◽  
Before And After ◽  
Higher Order Aberration ◽  
Best Corrected Visual Acuity

Introduction. To examine the corneal total higher-order aberrations before and after the excision of an overhanging bleb that developed following trabeculectomy. Case Presentation. Two patients who developed overhanging blebs following trabeculectomy with a fornix-based conjunctival flap using mitomycin C (MMC) were assessed. We measured the corneal total higher-order aberrations for a 4 mm pupil diameter using the TOPCON KR-1W wavefront analyzer and the visual acuity before and after bleb excision. The corneal total higher-order aberration (HOA) improved from 0.50 μm to 0.38 μm in case 1 and from 0.59 μm to 0.49 μm in case 2 after bleb excision. The intraocular pressure was identical before and after bleb excision in both cases. No significant changes in the best-corrected visual acuity (BCVA) were noted in case 1; however, BCVA was improved from 20/25 to 20/20 in case 2. Both cases showed improvements in the symptoms of dysesthesia. Conclusion. Excision of the overhanging bleb developed following trabeculectomy may have beneficial possibility in some cases where corneal total HOA is affected and reduces the symptoms of dysesthesia.

Changes in Higher Order Aberrations after Wavefront-Guided Prk for Correction of Low to Moderate Myopia and Myopic Astigmatism: Two-Year Follow-Up

2007 ◽  
Vol 17 (4) ◽  
pp. 507-514 ◽  
Author(s):  
D. Wygledowska-Promienska ◽  
I. Zawojska
Keyword(s):  
Visual Acuity ◽  
Excimer Laser ◽  
Spherical Aberration ◽  
Higher Order ◽  
Control Group ◽  
Higher Order Aberrations ◽  
Order Root ◽  
Group 2 ◽  
Myopic Astigmatism ◽  
Group 1

Purpose To assess efficacy, safety, and changes in higher order aberrations after wavefront-guided photorefractive keratectomy (PRK) in comparison with conventional PRK for low to moderate myopia with myopic astigmatism using a WASCA Workstation with the MEL 70 G-Scan excimer laser. Methods A total of 126 myopic or myopic-astigmatic eyes of 112 patients were included in this retrospective study. Patients were divided into two groups: Group 1, the study group; and Group 2, the control group. Group 1 consisted of 78 eyes treated with wavefront-guided PRK. Group 2 consisted of 48 eyes treated with spherocylindrical conventional PRK. Results Two years postoperatively, in Group 1, 5% of eyes achieved an uncorrected visual acuity (UCVA) of 0.05; 69% achieved a UCVA of 0.00; 18% of eyes experienced enhanced visual acuity of −0.18 and 8% of −0.30. In Group 2, 8% of eyes achieved a UCVA of 0.1; 25% achieved a UCVA of 0.05; and 67% achieved a UCVA of 0.00 according to logMAR calculation method. Total higher-order root-mean square increased by a factor 1.18 for Group 1 and 1.6 for Group 2. There was a significant increase of coma by a factor 1.74 in Group 2 and spherical aberration by a factor 2.09 in Group 1 and 3.56 in Group 2. Conclusions The data support the safety and effectiveness of the wavefront-guided PRK using a WASCA Workstation for correction of low to moderate refractive errors. This method reduced the number of higher order aberrations induced by excimer laser surgery and improved uncorrected and spectacle-corrected visual acuity when compared to conventional PRK.

Tube Shunt Surgery Versus Trabeculectomy in Eyes with Prior Ocular Surgery and Uncontrolled Glaucoma

2020 ◽  
pp. 103-108
Author(s):  
Alan D. Penman ◽  
Kimberly W. Crowder ◽  
William M. Watkins
Keyword(s):  
Mitomycin C ◽  
Medical Therapy ◽  
Cataract Extraction ◽  
Glaucoma Surgery ◽  
Shunt Surgery ◽  
Ocular Surgery ◽  
Lens Implantation ◽  
Surgical Options ◽  
Tube Versus ◽  
Tube Shunt

The Tube Versus Trabeculectomy (TVT) Study was a randomized clinical trial comparing tube shunt surgery to trabeculectomy with mitomycin C in patients with uncontrolled glaucoma (intraocular pressure (IOP) ≥18 mm Hg and ≤40 mm Hg on maximum tolerated medical therapy) who had previously undergone cataract extraction with intraocular lens implantation and/or failed filtering surgery. The study did not demonstrate clear superiority of one glaucoma operation over the other, but indicated that both tube shunt surgery and trabeculectomy with mitomycin C were viable surgical options for treating medically uncontrolled glaucoma in this group of patients. Both procedures were associated with similar IOP reduction and use of supplemental medical therapy at 5 years. Additional glaucoma surgery was needed more frequently after trabeculectomy with MMC than tube shunt placement.

Wavefront aberrations in children with different types of amblyopia

The Eye ◽  
2020 ◽  
Vol 22 (129) ◽  
pp. 14-20
Author(s):  
Ekaterina Naumova ◽  
Elena Titarenko
Keyword(s):  
High Efficiency ◽  
Previous History ◽  
Higher Order ◽  
Control Group ◽  
Higher Order Aberrations ◽  
Unsuccessful Treatment ◽  
Different Types ◽  
Function Analyzer ◽  
Positive Treatment ◽  
Pre Treatment

Purpose. To quantify and characterize higher-order aberrations in eyes of children with amblyopia caused by different etiology factors; to evaluate the relationship between the wavefront profile and the effectiveness of the amblyopia treatment. Material and methods. This study involved 26 children (52 eyes) from 3 to 9 years old (average age 6.2±3 years) with different types of amblyopia: unilateral amblyopia due to impaired binocular vision and anisometropia, as well as unilateral or bilateral amblyopia caused by hyperopia. Patients were divided into four groups depending on the effectiveness of pleoptic treatment: 14 children (24 eyes) – with positive treatment results, 8 children (12 eyes) – with refractory amblyopia, 4 pre-treatment newly diagnosed patients (6 eyes) without previous history of optical correction, and 10 non-amblyopic contralateral eyes (control group). All patients had central fixation and didn`t have any severe systemic diseases. Higher-order aberrations were measured with iTrace Visual Function Analyzer (Tracey Technologies, Houston, TX) after instillation of 1% cyclopentolate eyedrops. Results and discussion. Wavefront profiles were significantly different in the studied groups. Total spherical aberrations and astigmatism were significantly higher in group with refractory amblyopia (-0.53±1.19 and 2.25±1.07, p=0.02) compared with all the other groups: the group of patients before pleoptic treatment (-0.17±0.23 and 1.79±1.47), group treated with high efficiency (-0.31±0.81 and 1.04±0.13) and with control group (-0.13±0.17 and 1.38±0.11). Total coma-like aberrations didn`t show statistically significant differences in all studied groups (р=0.06). The level of corneal higher-order aberrations (total, coma, spherical) in all three amblyopic groups was higher than in the control group without amblyopia. Conclusion. We revealed statistically significant differences in the wavefront profiles in children with amblyopia of various etiologies in comparison with the control group, including higher-order aberrations. The data obtained indicate that an amblyopic eye with hyperopia has higher level of spherical aberrations and astigmatism due to higher level of internal HOAs, particularly spherical aberrations and astigmatism, which is typical for patients with unsuccessful treatment. Therefore, that type of aberrations is likely to be the main cause of refractory amblyopia.

scholarly journals The Effect of the Degree of Astigmatism on Optical Quality in Children

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Jing Gao ◽  
Xiao-xia Wang ◽  
Lin Wang ◽  
Yuan Sun ◽  
Rui-fen Liu ◽  
...  
Keyword(s):  
Pupil Diameter ◽  
Objective Evaluation ◽  
Optical Quality ◽  
Higher Order ◽  
Optical Parameters ◽  
Inclusion Criteria ◽  
Higher Order Aberrations ◽  
Evaluation Parameters ◽  
Important Objective ◽  
High Order Aberrations

Purpose. To investigate the effect of the degree of astigmatism on optical quality in children. The important objective evaluation parameters we focus on include the RMS of the high-order aberrations, MTF, and PSF. Methods. The children, age ranging from 7 to 10 years old, underwent an optometry examination. Fifty-nine children who met the inclusion criteria were divided into three groups: A (1.0 D ≤ astigmatism < 2.0 D), B (2.0 D ≤ astigmatism < 3.0 D), and C (3.0 D ≤ astigmatism < 4.0 D). The OPD-SCAN-III aberrometer was used to measure PSF, MTF, and other optical parameters. Total higher-order aberrations, total coma aberrations, total spherical aberrations, and total trefoil aberrations corresponding to the RMS value, the AR value of MTF, and the SR value of PSF with a 4 mm pupil diameter were assessed. Results. RMS-HO, RMS-T.Coma, RMS-T.Tre, and RMS-T.Sph in the three groups were significantly increased with increasing the degree of astigmatism, while there were no significant differences in RMS-T.Sph between the groups. The AR value and the SR value decreased with increasing degree of astigmatism, and there were significant differences in the AR value and the SR value. Conclusion. Astigmatism has a significant influence on the higher-order aberrations, MTF, and PSF in the children. The effect of astigmatism value on the optical quality is mainly reflected in the change in these three parameters.

scholarly journals Abnormal higher order aberrations in anisometropic amblyopia

2020 ◽  
Author(s):  
Lingyi Zhang ◽  
Meng Liao ◽  
Wenqiu Zhang ◽  
Longqian Liu
Keyword(s):  
Visual Acuity ◽  
Pearson Correlation ◽  
Higher Order ◽  
Control Group ◽  
Third Order ◽  
Higher Order Aberrations ◽  
Regular Treatment ◽  
Anisometropic Amblyopia ◽  
Pearson Correlation Test ◽  
Order Root

Abstract Background The study compared ocular higher-order aberrations (HOAs) between monocular anisometropic amblyopia children and similar anisometropia children with normal best-corrected visual acuity (BCVA). The amblyopia eyes could not reach the standard BCVA level of their age even after several months' regular treatment of amblyopia. We tried to find if these intractable amblyopia eyes have abnormal HOAs. Methods Fifty school-aged children (5–9 years) with hyperopic anisometropia were recruited at West China hospital clinic. Each subject shall be reexamined once every three months, four consecutive reexaminations for 12 months, of which only 25 subjects with normal BCVA after wearing glasses shall be included in the control group. The rest 25 subjects were treated by glasses and six months’ patching. Their interocular difference of visual acuity was still more than or equal to LogMAR 0.2, and the eyes with poor visual acuity did not reach the normal level in the twelfth month. These subjects were included in the amblyopia group. The BCVA, HOAs (5 mm pupil diameter), and axial length were recorded for all subjects. Results There were significant differences of higher order aberrations in C (3, -3) between the amblyopia eyes and the other three groups of eyes with normal BCVA (all p < 0.05). There were significant differences of higher-order aberrations in third-order root-mean-square aberrations(RMS) between the amblyopia eyes and the low-diopter eyes from two subject groups(both p < 0.05). Compared to high-diopter eyes in the control group, there were a significantly higher C(3,-3) in all amblyopia eyes and a significantly higher third-order RMS (p = 0.040) in the moderate-to-severe amblyopia group. In the Pearson correlation test, the C(3,-3) and third order RMS demonstrated statistically significant correlations with BCVA ( (r=-0.19, p = 0.04; r = 0.37, p < 0.01). Conclusions The anisometropic amblyopia eyes had different HOAs from the eyes with normal visual acuity. The third-order aberrations were the primary abnormal higher-order aberration in amblyopia eyes.

scholarly journals Higher order aberrations of the eye: Part two

2016 ◽  
Vol 75 (1) ◽  
Author(s):  
Marsha Oberholzer ◽  
Wayne D.H. Gillan ◽  
Alan Rubin
Keyword(s):  
Pupil Diameter ◽  
Tear Film ◽  
Crystalline Lens ◽  
Higher Order ◽  
Refractive Errors ◽  
Measuring Apparatus ◽  
Higher Order Aberrations ◽  
Wavefront Aberrations ◽  
Human Eye

This article is the second in a series of two articles, which provides a discussion of the factors that may possibly contribute to variable results when wavefront aberrations of the human eye are measured. Some of the factors discussed in this article are the influences that refractive errors (specifically myopia and astigmatism), pupil diameter, accommodation of the crystalline lens, age, mydiatric drops and the integrity of the tear film may have on these wavefront measurements. The first article in the series explained the general principles of higher order aberrations (HOAs), as well as HOAs of importance in the eye and the measuring apparatus used to measure HOAs of the eye.Keywords: wavefront aberrations; aberrometry

Efficacy and safety of blepharoptosis repair after incisional glaucoma surgery

2021 ◽  
pp. 112067212110066
Author(s):  
Allisa J Song ◽  
Cheryl L Khanna ◽  
Sepideh Jamali ◽  
Gavin W Roddy ◽  
Lilly H Wagner
Keyword(s):  
Revision Surgery ◽  
Retrospective Chart Review ◽  
Glaucoma Surgery ◽  
Glaucoma Drainage Device ◽  
Control Group ◽  
Increased Risk ◽  
Potential Risk Factors ◽  
History Of ◽  
Surgery Outcomes ◽  
Ptosis Surgery

Purpose: There is an increased risk for development of blepharoptosis after incisional glaucoma surgery. Data on safety and efficacy of ptosis repair in this group of patients in limited. The goal of this study is to evaluate outcomes and identify potential risk factors for failure of ptosis repair in eyes with history of incisional glaucoma surgery. Methods: A retrospective chart review was performed of all patients who underwent incisional glaucoma surgery, specifically trabeculectomy or implantation of glaucoma drainage device (GDD), and subsequent ptosis repair at a single institution from 2009 to 2019. Ptosis surgery outcomes were compared to a control group who underwent ptosis repair after cataract surgery. Results: Seventy-eight eyes of 64 patients were included in the glaucoma surgery group. The rate of severe ptosis (margin reflex distance 1 ⩽ 0 mm) among glaucoma surgery patients was higher compared to control (35 of 78 (44.9%) vs 23 of 82 (28.6%). Ptosis repair was successful in 59 of 78 eyes (75.6%), which was similar to control. Risk for revision surgery was increased more than five-fold in the GDD group compared to control. There were no cases of early or late bleb-related complications. Conclusions: Ptosis repair can be performed safely in patients after incisional glaucoma surgery. Müller muscle conjunctival resection and external levator advancement are equally effective. Patients with history of GDD should be advised about the potentially increased risk of need for revision surgery.

Prognostic factors in trabeculectomy with mitomycin C having history of previous glaucoma surgery

2013 ◽  
Vol 57 (6) ◽  
pp. 514-519 ◽  
Author(s):  
Nanako Awai-Kasaoka ◽  
Toshihiro Inoue ◽  
Masaru Inatani ◽  
Yuji Takihara ◽  
Minako Ogata-Iwao ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Mitomycin C ◽  
Glaucoma Surgery ◽  
History Of

scholarly journals Monochromatic higher order aberrations in highly myopic eyes with Staphyloma

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Santiago Delgado-Tirado ◽  
Alberto López-Miguel ◽  
Yazmin Báez-Peralta ◽  
Lucía González-Buendía ◽  
Itziar Fernández ◽  
...  
Keyword(s):  
High Myopia ◽  
Spherical Aberration ◽  
Higher Order ◽  
Posterior Pole ◽  
Intraocular Lenses ◽  
Analysis Of Covariance ◽  
Control Group ◽  
Higher Order Aberrations ◽  
Posterior Staphyloma ◽  
Clinical Counselling

Abstract Background Prevalence of high myopia is continuously increasing, thus, patients affected with staphyloma are abundant worldwide. Assessment of the quality of vision in these patients is mandatory for a proper clinical counselling, specially when undergoing surgical procedures that require intraocular lenses implantation. Thus, the purpose of the study was to assess monochromatic higher order aberrations (HOAs) in highly myopic eyes with staphyloma with or without a dome-shaped macula. Methods Participants underwent spectral-domain optical coherence tomography, ocular axial biometry, dual Scheimpflug photography and integrated Placido disk topography, and Hartmann-Shack wavefront analysis. Five groups were evaluated: a low-moderate myopia control group (< 6.00 diopters, n = 31) and four high myopia (≥6.00 diopters) groups: eyes without staphyloma (n = 18), eyes with inferior staphyloma (n = 14), eyes with posterior staphyloma without dome-shaped macula (n = 15) and eyes with posterior staphyloma with dome-shaped macula (n = 17). Subsequently, two new groups (including all participants) were created to assess differences between myopia with and without staphyloma. One-way analysis of covariance was performed using age and lens densitometry as covariates. Results Statistically significant (p ≤ 0.05) differences in anterior corneal fourth-order HOAs were observed between the low-moderate myopia and no-dome-shaped macula (Mean: 0.16 μm) and dome-shaped macula posterior staphyloma groups (Mean: 0.12 μm) in younger patients (≤45 years old). The same groups also showed (p ≤ 0.05) significant differences for anterior corneal primary spherical aberration (Mean: 0.19 and 0.13 μm, respectively). In addition, anterior corneal tetrafoil was significantly higher (p = 0.04) in dome-shaped macula compared to no-dome-shaped macula (Mean: 0.18 vs 0.06 μm, respectively). When all participants were grouped together, significantly lower mean anterior corneal primary spherical aberration (0.15 μm vs. 0.27 μm, p = 0.004) and higher internal primary spherical aberration (0.04 μm vs. -0.06 μm, p = 0.04) was observed in staphyloma compared to no-staphyloma myopic patients. Conclusions Eyes with high myopia and staphyloma have less positive anterior corneal primary spherical aberration and less negative internal primary spherical aberration, suggesting that the anterior corneal surface tends to mimic in a specular fashion the posterior pole profile. This corneal behaviour appears to change in patients older than 45 years.

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