scholarly journals Delayed Fever and Acute Kidney Injury in Patients with Urinary Tract Infection

2020 ◽  
Vol 9 (11) ◽  
pp. 3486
Author(s):  
Kun-Lin Lu ◽  
Chih-Yen Hsiao ◽  
Chao-Yi Wu ◽  
Chieh-Li Yen ◽  
Chung-Ying Tsai ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Urinary Tract Infection ◽  
Renal Function ◽  
Urinary Tract ◽  
Tract Infection ◽  
Hospital Stay ◽  
Kidney Injury ◽  
Lower Baseline ◽  
Clinical Awareness ◽  
Baseline Renal Function

The presence of fever has long been a warning sign of severe urinary tract infection (UTI). However, we previously identified that inpatients with afebrile UTI had an increased risk of developing acute kidney injury (AKI). After expanding this cohort, 1132 inpatients with UTI diagnosed between January 2006 and April 2019 were analyzed. Overall, 159 (14%) of these patients developed AKI; bacteremia, urolithiasis, septic shock, hypertension, lower baseline renal function, marked leukocytosis, and the absence of fever were independently linked to AKI. When we further studied the cohort of inpatients with fever during hospitalization, we identified a group of “delayed fever” UTI inpatients who did not have fever as their initial presentation. Compared to patients presenting with fever at the emergency department, patients with delayed fever tended to be younger and have less frequent infection with Escherichia coli, more frequent AKI, upper tract infection, and a longer hospital stay. Despite the initial absence of fever, these patients demonstrated larger extents of elevations in both serum white blood cell counts and C-reactive protein levels. In short, besides UTI patients with lower baseline renal function that remain afebrile during their hospital stay, clinical awareness of the increased incidence of AKI in younger patients with “delayed fever” should also be noted.

scholarly journals Acute kidney injury in kidney rupture and urinary tract infection in A 6-year-old-boy

2017 ◽  
Vol 48 (2) ◽  
pp. 142
Author(s):  
Dinna Auliawati ◽  
Gusti Ayu Putu Nilawati ◽  
I Ketut Suarta ◽  
Wayan Yudiana
Keyword(s):  
Acute Kidney Injury ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Kidney Injury ◽  
Kidney Rupture

scholarly journals Anderson-Hynes Pyeloplasty in Children: Nonintubated Versus Intubated

2012 ◽  
Vol 35 (2) ◽  
pp. 59-61
Author(s):  
Gazi Zahirul Hasan ◽  
AKM Zahid Hossain ◽  
Md Ruhul Amin ◽  
Shafiqul Hoque ◽  
MTH Siddiqui
Keyword(s):  
Urinary Tract Infection ◽  
Renal Function ◽  
Urinary Tract ◽  
Tract Infection ◽  
Hospital Stay ◽  
Paediatric Surgery ◽  
Dhaka City ◽  
Additional Advantage ◽  
Differential Renal Function ◽  
Medical University

Objective: To compare between nonintubated versus intubated Anderson-Hynes (AH) pyeloplasty in children.Study Design: Prospective studyStudy place: Department of Paediatric Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh and some private clinics of Dhaka city. Study period: March 2001 to December 2008.Subjects: A total of 75 patients were included in this study. They were divided in two groups. Nonintubated Anderson-Hynes pyeloplasty was done in 45 patients and intubated Anderson-Hynes pyeloplasty was done in 30 patients.Results: The anastomotic leakage of urine, urinary tract infection, hospital stay and improvement of differential renal function were assessed post operatively in both nonintubated and intubated groups. This study showed that there was no anastomotic failure and no post operative urinary tract infection in either group. The percentage of improvement of differential renal function is almost same in both the groups. The post operative hospital stay was markedly reduced in nonintubated Anderson-Hynes pyeloplasty. In this study the post operative hospital stay in nonintubated group was average 6 days and it was average 16.5 days in intubated group.Conclusion: From this study it may be concluded that the effects of nonintubated AH pyeloplasty is as good as intubated one but an additional advantage of significantly less post operative hospital stay was observed in nonintubated group.DOI: http://dx.doi.org/10.3329/bjch.v35i2.10378  Bangladesh J Child Health 2011; Vol 35 (2): 59-61

scholarly journals Urolithiasis Is a Risk Factor for Uroseptic Shock and Acute Kidney Injury in Patients With Urinary Tract Infection

2019 ◽  
Vol 6 ◽  
Author(s):  
Chih-Yen Hsiao ◽  
Tsung-Hsien Chen ◽  
Yi-Chien Lee ◽  
Meng-Chang Hsiao ◽  
Peir-Haur Hung ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Urinary Tract Infection ◽  
Risk Factor ◽  
Urinary Tract ◽  
Tract Infection ◽  
Kidney Injury

scholarly journals Clinical Application Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 as Indicators of Inflammation Persistence and Acute Kidney Injury in Children with Urinary Tract Infection

2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Stanislava Petrovic ◽  
Natasa Bogavac-Stanojevic ◽  
Amira Peco-Antic ◽  
Ivana Ivanisevic ◽  
Jelena Kotur-Stevuljevic ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Kidney Injury ◽  
The Novel ◽  
Neutrophil Gelatinase Associated Lipocalin ◽  
Significant Difference ◽  
Kidney Injury Molecule 1 ◽  
Neutrophil Gelatinase

Background. The aim of this study was to examine the novel renal biomarkers neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) to assist pediatricians in the assessment of longer duration of inflammation and acute kidney injury (AKI) development during urinary tract infection (UTI).Methods. The patients enrolled in the study comprised 50 children (mean age was 6 months) with UTI. NGAL in serum and urine (sNGAL and uNGAL, resp.) and KIM-1 in urine were measured by enzyme-linked immunosorbent assays.Results. uNGAL levels in subjects with longer duration of inflammation were higher (115.37 ng/mL) than uNGAL levels in subjects with shorter duration of inflammation (67.87 ng/mL,P=0.022). Difference in sNGAL and KIM-1 levels was not significant (P=0.155andP=0.198, resp.). Significant difference was seen in KIM-1 excretion among groups with and without AKI (P=0.038). KIM-1 was not able to discriminate between subjects with and without AKI (area under the curves (AUC) = 0.620,P=0.175).Conclusions. uNGAL cannot be used for screening of the duration of inflammation during UTI. Accuracy of KIM-1 in screening of AKI development in children with UTI is low. We suggest larger studies to check the negative predictive value of KIM-1 for the development of AKI.

Acute kidney injury in pregnancy

2015 ◽  
Author(s):  
Kate Wiles ◽  
Catherine Nelson-Piercy
Keyword(s):  
Acute Kidney Injury ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Adverse Pregnancy Outcome ◽  
Post Partum ◽  
Kidney Injury ◽  
Obstructive Nephropathy ◽  
Elevated Liver Enzymes ◽  
In Pregnancy

The diagnosis of acute kidney injury in pregnancy is complicated by physiological changes to both kidney and circulation; although a serum creatinine of higher than 90 μ‎‎‎mol/L is considered diagnostic of kidney injury in pregnancy. The aetiology of acute kidney injury in pregnancy mirrors that of the non-pregnant patient with the addition of pregnancy-specific conditions such as pre-eclampsia, HELLP syndrome (haemolysis, elevated liver enzymes, low platelets), post-partum haemorrhage, and acute fatty liver of pregnancy. In early pregnancy, the major additional concerns are septic abortion and hyperemesis. Urinary tract infection is common in pregnancy. Surveillance and treatment thresholds reflect the recognized association between urinary tract infection and adverse pregnancy outcome. Obstructive nephropathy is difficult to diagnose in pregnancy due to a physiological dilatation of the renal tract. Radiological assessment and intervention to the renal tract in pregnancy are also discussed in this chapter.

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