Exploiting Nonlinear Photoacoustic Signal Generation in Gold Nanospheres for Selective Detection in Serial 3D PA Tomography

The photoacoustic (PA) signal amplitude measured in gold nanosphere suspensions has been shown to increase nonlinearly with the incident excitation fluence. In this work, this effect is exploited to recover the spatial distribution of gold nanoparticles in tomographic 3D photoacoustic (PA) images against the background contrast provided by absorbers that exhibit a linear relationship between the PA signal amplitude and the fluence. Serial tomographic PA images of a tissue phantom containing gold nanospheres and a tissue-mimicking absorber were acquired. By assessing the linearity of the PA intensity voxel by voxel, the spatial distribution of the gold nanosphere suspension was recovered. The method is shown to enable the robust detection of gold nanoparticles.

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Quenching of nonlinear photoacoustic signal generation in gold nanoparticles through coating

Nanoscale Advances ◽

10.1039/d0na00205d ◽

2020 ◽

Vol 2 (7) ◽

pp. 2699-2704

Author(s):

Genny A. Pang ◽

Christoph Haisch ◽

Jan Laufer

Keyword(s):

Gold Nanoparticles ◽

Photoacoustic Signal ◽

Signal Generation ◽

Gold Nanospheres ◽

Particle Coating ◽

Biochemical Sensing

The nonlinear photoacoustic signal behavior from gold nanospheres is suppressed through particle coating, which can be used for biochemical sensing.

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Nanosensor Composed of Nitrogen-Doped Carbon Dots and Gold Nanoparticles for Highly Selective Detection of Cysteine with Multiple Signals

Analytical Chemistry ◽

10.1021/ac503595y ◽

2015 ◽

Vol 87 (4) ◽

pp. 2195-2203 ◽

Cited By ~ 132

Author(s):

Jianhui Deng ◽

Qiujun Lu ◽

Yuxin Hou ◽

Meiling Liu ◽

Haitao Li ◽

...

Keyword(s):

Gold Nanoparticles ◽

Carbon Dots ◽

Selective Detection ◽

Multiple Signals ◽

Nitrogen Doped ◽

Doped Carbon Dots ◽

Nitrogen Doped Carbon

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Sensitive and Selective Detection of Antibiotic D-Penicillamine Based on a Dual-Mode Probe of Fluorescent Carbon Dots and Gold Nanoparticles

Journal of Fluorescence ◽

10.1007/s10895-018-2307-3 ◽

2018 ◽

Vol 28 (6) ◽

pp. 1405-1412 ◽

Cited By ~ 7

Author(s):

Hongwei Ge ◽

Kui Zhang ◽

Huan Yu ◽

Ji Yue ◽

Long Yu ◽

...

Keyword(s):

Gold Nanoparticles ◽

Carbon Dots ◽

Selective Detection ◽

Dual Mode ◽

Fluorescent Carbon Dots ◽

Fluorescent Carbon

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Visual and fluorescent assays for selective detection of beta-amyloid oligomers based on the inner filter effect of gold nanoparticles on the fluorescence of CdTe quantum dots

Biosensors and Bioelectronics ◽

10.1016/j.bios.2016.05.066 ◽

2016 ◽

Vol 85 ◽

pp. 625-632 ◽

Cited By ~ 55

Author(s):

Ning Xia ◽

Binbin Zhou ◽

Nanbing Huang ◽

Mengsha Jiang ◽

Jiebing Zhang ◽

...

Keyword(s):

Quantum Dots ◽

Gold Nanoparticles ◽

Inner Filter Effect ◽

Beta Amyloid ◽

Cdte Quantum Dots ◽

Selective Detection ◽

Filter Effect ◽

Amyloid Oligomers

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The selective detection of Fe3+ ions using citrate-capped gold nanoparticles

Analytical Biochemistry ◽

10.1016/j.ab.2021.114453 ◽

2021 ◽

pp. 114453

Author(s):

Xinhua Meng ◽

Bijing Lei ◽

Na Qi ◽

Bochu Wang

Keyword(s):

Gold Nanoparticles ◽

Selective Detection

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RNA aptasensor based on gold nanoparticles for selective detection of neomycin B, molecular approach

Journal of the Iranian Chemical Society ◽

10.1007/s13738-019-01708-0 ◽

2019 ◽

Vol 16 (11) ◽

pp. 2389-2400 ◽

Cited By ~ 2

Author(s):

Mohammad Khavani ◽

Mohammad Izadyar ◽

Mohammad Reza Housaindokht

Keyword(s):

Gold Nanoparticles ◽

Selective Detection ◽

Molecular Approach ◽

Neomycin B

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Multipole Radiations from Large Gold Nanospheres Excited by Evanescent Wave

Nanomaterials ◽

10.3390/nano9020175 ◽

2019 ◽

Vol 9 (2) ◽

pp. 175

Author(s):

Jingdong Chen ◽

Jin Xiang ◽

Shuai Jiang ◽

Qiaofeng Dai ◽

Shaolong Tie ◽

...

Keyword(s):

Evanescent Wave ◽

Polarized Light ◽

Electric Quadrupole ◽

Photonic Devices ◽

High Order ◽

Gold Nanospheres ◽

Reflected Light ◽

Gold Nanosphere ◽

Scattering Light ◽

Plasmon Modes

We proposed the use of the evanescent wave generated in a total internal reflection configuration to excite large gold nanospheres and investigated the radiations of the high-order plasmon modes supported in gold nanospheres. It was revealed that the evanescent wave excitation is equivalent to the excitation by using both the incident and reflected light, offering us the opportunity to control the orientation of the electric field used to excite nanoparticles. In addition, it was found that the scattering light intensity is greatly enhanced and the background noise is considerably suppressed, making it possible to detect the radiations from high-order plasmon modes. Moreover, the influence of the mirror images on the scattering induced by a metal substrate is eliminated as compared with the surface plasmon polariton excitation. By exciting a gold nanosphere with s-polarized light and detecting the scattering light with a p-polarized analyzer, we were able to reveal the radiation from the electric quadrupole mode of the gold nanosphere in both the spatial and the frequency domains. Our findings are important for characterizing the radiations from the high-order modes of large nanoparticles and useful for designing nanoscale photonic devices.

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