scholarly journals Reliability and Correlation of Different Devices for the Evaluation of Primary Implant Stability: An In Vitro Study

Materials ◽  
2021 ◽  
Vol 14 (19) ◽  
pp. 5537
Author(s):  
Perry Raz ◽  
Haya Meir ◽  
Shifra Levartovsky ◽  
Maia Peleg ◽  
Alon Sebaoun ◽  
...  
Keyword(s):  
In Vitro Study ◽  
Implant Design ◽  
Implant Stability ◽  
High Positive Correlation ◽  
Primary Implant ◽  
Conical Connection ◽  
Vitro Model ◽  
Implant Length ◽  
Positive Significant Correlation

Our aim was to analyze the correlation between the IT evaluated by a surgical motor and the primary implant stability (ISQ) measured by two RFA devices, Osstell and Penguin, in an in vitro model. This study examines the effect of bone type (soft or dense), implant length (13 mm or 8 mm), and implant design (CC: conical connection; IH: internal hexagon), on this correlation. Ninety-six implants were inserted using a surgical motor (IT) into two types of synthetic foam blocks. Initial measurements for both the peak IT and ISQ were recorded at the point when implant insertion was stopped by the surgical motor, and the final measurements were recorded when the implant was completely inserted into the synthetic blocks using only the RFA devices. Our null hypothesis was that there is a good correlation between the devices, independent of the implant length, design, or bone type. We found a positive, significant correlation between the IT, and the Osstell and Penguin devices. Implant length and bone type did not affect this correlation. The correlation between the devices in the CC design was maintained; however, in the IH design it was maintained only between the RFA devices. We concluded that there is a high positive correlation between the IT and ISQ from a mechanical perspective, which was not affected by bone type or implant length but was affected by the implant design.

scholarly journals Influence of Implant Design and Under-Preparation of the Implant Site on Implant Primary Stability. An In Vitro Study

2020 ◽  
Vol 17 (12) ◽  
pp. 4436 ◽  
Author(s):  
Mariano Herrero-Climent ◽  
Bernardo Ferreira Lemos ◽  
Federico Herrero-Climent ◽  
Carlos Falcao ◽  
Helder Oliveira ◽  
...  
Keyword(s):  
In Vitro Study ◽  
Primary Stability ◽  
Implant Design ◽  
Insertion Torque ◽  
Bovine Bone ◽  
Preparation Technique ◽  
Implant Stability ◽  
The One ◽  
Two Parameters

The aim of this study was to evaluate the effects of different implant sites an under-preparation sequence associated with two different implant designs on implant primary stability measured by two parameters: insertion torque (IT) and implant stability quotient (ISQ). It used two different implants: one cylindrical as a control and another one with a tapered design. The implants were inserted in type III fresh humid bovine bone and four drilling sequences were used: one control, the one proposed by the implant company (P1), and three different undersized (P2, P3 and P4). P2 was the same as P1 without the cortical drill, P3 was without the last pilot drill and P4 was without both of them. The sample size was n = 40 for each of the eight groups. Final IT was measured with a torquemeter and the ISQ was measured with Penguin resonance frequency analysis. Results showed that both ISQ and IT have a tendency to increase as the preparation technique reduces the implant site diameter when compared with the standard preparation, P1. The preparations without cortical drill, P2 and P4, showed the best results when compared with the ones with a cortical drill. Tapered implants always showed higher or the same ISQ and IT values when compared with the cylindrical implants. Giving the limitations of this study, it can be concluded that reducing implant preparation can increase IT and ISQ values. Removing the cortical drill and the use of a tapered design implant are also effective methods of increasing primary implant stability.

Insertion torque/time integral as a measure of primary implant stability

2020 ◽  
Vol 65 (6) ◽  
pp. 729-733
Author(s):  
Tanja Grobecker-Karl ◽  
Matthias Karl ◽  
Constanze Steiner
Keyword(s):  
Cortical Layer ◽  
Implant Design ◽  
Insertion Torque ◽  
Resonance Frequency Analysis ◽  
Implant Stability ◽  
Time Integral ◽  
Primary Implant ◽  
Medium Quality ◽  
Bone Level

AbstractThe goal of this in vitro study was to determine the insertion torque/time integral for three implant systems. Bone level implants (n = 10; BLT – Straumann Bone Level Tapered 4.1 mm × 12 mm, V3 – MIS V3 3.9 mm × 11.5 mm, ASTRA – Dentsply-Sirona ASTRA TX 4.0 mm × 13 mm) were placed in polyurethane foam material consisting of a trabecular and a cortical layer applying protocols for medium quality bone. Besides measuring maximum insertion torque and primary implant stability using resonance frequency analysis (RFA), torque time curves recorded during insertion were used for calculating insertion torque/time integrals. Statistical analysis was based on ANOVA, Tukey’s honest differences test and Pearson product moment correlation (α = 0.05). Significantly greater mean maximum insertion torque (59.9 ± 4.94 Ncm) and mean maximum insertion torque/time integral (961.64 ± 54.07 Ncm∗s) were recorded for BLT implants (p < 0.01). V3 showed significantly higher mean maximum insertion torque as compared to ASTRA (p < 0.01), but significantly lower insertion torque/time integral (p < 0.01). Primary implant stability did not differ significantly among groups. Only a single weak (r = 0.61) but significant correlation could be established between maximum insertion torque and insertion torque/time integral (p < 0.01) when all data from all three implant groups were pooled. Implant design (length, thread pitch) seems to affect insertion torque/time integral more than maximum insertion torque.

scholarly journals Influence of Cortical Layer and Surgical Techniques on the Primary Implant Stability in Low-density Bone:An In Vitro Study

2021 ◽  
Vol 22 (2) ◽  
pp. 146-151
Author(s):  
Sampathkumar JayaKrishnaKumar ◽  
Rahmath S Shafiullah ◽  
Ramasubramanian Hariharan ◽  
Chitra S Krishnan ◽  
Navarasampatti S Azhagarasan ◽  
...  
Keyword(s):  
Surgical Techniques ◽  
In Vitro Study ◽  
Cortical Layer ◽  
Vitro Study ◽  
Low Density ◽  
Implant Stability ◽  
Primary Implant

scholarly journals Primary implant stability in a bone model simulating clinical situations for the posterior maxilla: an in vitro study

2016 ◽  
Vol 46 (4) ◽  
pp. 254 ◽  
Author(s):  
Ho-Chyul Han ◽  
Hyun-Chang Lim ◽  
Ji-Youn Hong ◽  
Su-Jin Ahn ◽  
Ji-Young Han ◽  
...  
Keyword(s):  
In Vitro Study ◽  
Vitro Study ◽  
Implant Stability ◽  
Bone Model ◽  
Primary Implant ◽  
Posterior Maxilla

scholarly journals Correction: Antonelli, A., et al. Can Bone Compaction Improve Primary Implant Stability? An In Vitro Comparative Study with Osseodensification Technique. Applied Sciences 2020, 10, 8623

2021 ◽  
Vol 11 (8) ◽  
pp. 3427
Author(s):  
Alessandro Antonelli ◽  
Francesco Bennardo ◽  
Ylenia Brancaccio ◽  
Selene Barone ◽  
Felice Femiano ◽  
...  
Keyword(s):  
Applied Sciences ◽  
Comparative Study ◽  
Implant Stability ◽  
Primary Implant

The author wishes to make the following corrections to this paper [...]

scholarly journals Effect of Lignocaine Concentration on Human Fibroblasts Growth in Eyes Undergoing Trabeculectomy: An in vitro Study

2018 ◽  
Vol 3 (3) ◽  
pp. 1-10 ◽  
Author(s):  
Madhuravasal Krishnan Janani ◽  
Venkatakrishnan Jaichandran ◽  
Hajib Narahari Rao Madhavan ◽  
Lingam Vijaya ◽  
Ronnie Jacob George ◽  
...  
Keyword(s):  
Culture Medium ◽  
In Vitro Model ◽  
Morphological Changes ◽  
Human Fibroblasts ◽  
Annexin V ◽  
In Vitro Study ◽  
Tenon’S Capsule ◽  
Tenon's Capsule ◽  
Vitro Model

Purpose: To evaluate the effect of lignocaine on growth and apoptosis indication of primary human Tenon’s capsule fibroblast (HTFs) in an in vitro model. Patients and Methods: Tenon’s capsule tissue obtained from patients undergoing trabeculectomy were grown in cell culture medium. The effect of different concentrations of lignocaine (0.5, 1.0, 1.5, and 2%) on the morphology and growth of the fibroblasts was studied using microscopy, cell viability, and proliferation assay, and apoptosis was detected using the FITC Annexin V Apoptosis Kit. Results: Morphological changes similar to those of apoptotic cells, including cytoplasmic vacuolation, shrinkage, and rounding were visualized in the cells treated with concentrations greater than 1.0% (i.e., 1.5, 2.0%). Though proliferation inhibition was found with all four concentrations (0.5–2.0%), the viability of cells decreased from 1.0% lignocaine. Conclusion: 0.5% lignocaine prevents proliferation of fibroblasts without causing apoptosis in vitro.

scholarly journals Factors Influencing Primary and Secondary Implant Stability—A Retrospective Cohort Study with 582 Implants in 272 Patients

2020 ◽  
Vol 10 (22) ◽  
pp. 8084
Author(s):  
Andreas Vollmer ◽  
Babak Saravi ◽  
Gernot Lang ◽  
Nicolai Adolphs ◽  
Derek Hazard ◽  
...  
Keyword(s):  
Risk Stratification ◽  
Predictive Factors ◽  
Healing Time ◽  
Resonance Frequency Analysis ◽  
Implant Stability ◽  
Implant Stability Quotient ◽  
Primary Implant ◽  
Preoperative Risk Stratification ◽  
Implant Length ◽  
Secondary Stability

The success rate of dental implants depends on primary and secondary stability. We investigate predictive factors for future risk stratification models. We retrospectively analyze 272 patients with a total of 582 implants. Implant stability is measured with resonance frequency analysis and evaluated based on the implant stability quotient (ISQ). A linear regression model with regression coefficients (reg. coeff.) and its 95% confidence interval (95% CI) is applied to assess predictive factors for implant stability. Implant diameter (reg. coeff.: 3.28; 95% CI: 1.89–4.66, p < 0.001), implant length (reg. coeff.: 0.67, 95% CI: 0.26–1.08, p < 0.001), and implant localization (maxillary vs. mandibular, reg. coeff.: −7.45, 95% CI: −8.70–(−6.20), p < 0.001) are significant prognostic factors for primary implant stability. An increase in ISQ between insertion and exposure is significantly correlated with healing time (reg. coeff.: 0.11, 95% CI: 0.04–0.19). Patients with maxillary implants have lower ISQ at insertion but show a higher increase in ISQ after insertion than patients with mandibular implants. We observe positive associations between primary implant stability and implant diameter, implant length, and localization (mandibular vs. maxillary). An increase in implant stability between insertion and exposure is significantly correlated with healing time and is higher for maxillary implants. These predictive factors should be further evaluated in prospective cohort studies to develop future preoperative risk-stratification models.

Studies in Cranial Suture Biology: In Vitro Cranial Suture Fusion

1996 ◽  
Vol 33 (2) ◽  
pp. 150-156 ◽  
Author(s):  
James P. Bradley ◽  
Jamie P. Levine ◽  
Christopher Blewett ◽  
Thomas Krummel ◽  
Joseph G. Mccarthy ◽  
...  
Keyword(s):  
Organ Culture ◽  
In Vitro Model ◽  
In Vitro Study ◽  
Cranial Base ◽  
Cranial Suture ◽  
Model Study ◽  
Suture Fusion ◽  
Vitro Model

The biology underlying craniosynostosis remains unknown. Previous studies have shown that the underlying dura mater, not the suture itself, signals a suture to fuse. The purpose of this study was to develop an in vitro model for cranial-suture fusion that would still allow for suture-dura interaction, but without the influence of tensional forces transmitted from the cranial base. This was accomplished by demonstrating that the posterior frontal mouse cranial suture, known to be the only cranial suture that fuses in vivo, fuses when plated with its dura in an organ-culture system. In such an organ-culture system, the sutures are free from both the influence of dural forces transmitted from the cranial base and from hormonal influences only available in a perfused system. For the cranial-suture fusion in vitro model study, the sagittal sutures (controls that remain patent in vivo) and posterior frontal sutures (that fuse in vivo) with the underlying dura were excised from 24-day-old euthanized mice, cut into 5 × 4 × 2-mm specimens, and cultured in a chemically defined, serum-free media. One hundred sutures were harvested at the day of sacrifice, then every 2 days thereafter until 30 days in culture, stained with H & E, and analyzed. A subsequent cranial-suture without dura in vitro study was performed in a similar fashion to the first study, but only the calvariae with the posterior frontal or sagittal sutures (without the underlying dura) were cultured. Results from the cranial-suture fusion in vitro model study showed that all sagittal sutures placed in organ culture with the underlying dura remained patent. More importantly, the posterior frontal sutures with the underlying dura, which were plated-down as patent at 24 days of age, demonstrated fusion after various growth periods in organ culture. In vitro posterior frontal mouse-suture fusion occurred in an anterior-to-posterior direction but in a delayed fashion, 4 to 7 days later than in vivo posterior frontal mouse-suture fusion. In contrast, the subsequent cranial-suture without dura in vitro study showed patency of all sutures, including the posterior frontal suture. These data from in vitro experiments indicate that: (1) mouse calvariae, sutures, and the underlying dura survive and grow in organ-culture systems for 30 days; (2) the local dura, free from external influences transmitted from the cranial base and hormones from distant sites, influences the cells of its overlying suture to cause fusion; and (3) without dura influence, all in vitro cranial sutures remained patent. By first identifying the factors involved in dural-suture signaling and then regulating these factors and their receptors, the biologic basis of suture fusion and craniosynostosis may be unraveled and used in the future to manipulate pathologic (premature) suture fusion.

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