scholarly journals Study on the Effects of Melatonin on Glycemic Control and Periodontal Parameters in Patients with Type II Diabetes Mellitus and Periodontal Disease

Medicina ◽  
2021 ◽  
Vol 57 (2) ◽  
pp. 140
Author(s):  
Diana-Maria Anton ◽  
Maria-Alexandra Martu ◽  
Marius Maris ◽  
George-Alexandru Maftei ◽  
Irina-Georgeta Sufaru ◽  
...  

Background and Objectives: There is evidence that melatonin could improve the periodontal status and also glycemic control of patients with diabetes mellitus. Therefore, the aim of this study was to assess the effects of scaling and root planing plus adjunctive systemic treatment with melatonin on periodontal parameters and glycemic control in patients with type 2 diabetes and chronic periodontitis. Materials and Methods: The study was conducted on 54 subjects with periodontitis and diabetes mellitus randomly assigned to the study group (n = 27, subjects with scaling and root planing + melatonin) or control group (n = 27, subjects with scaling and root planing + placebo). Periodontal parameters (probing depth—PD; clinical attachment loss—CAL; bleeding on probing—BOP; and hygiene level) and glycated hemoglobin (HbA1c) were assessed at baseline and 8 weeks after. Results: At baseline, there were no significant differences between groups, but at the second evaluation 8 weeks later the association of melatonin with the non-surgical periodontal therapy exerted statistically significant improvements, both in periodontal parameters, with a significant decrease in periodontal disease severity, and glycated hemoglobin when compared to the control subjects. Conclusions: In our study, combined non-surgical periodontal treatment and systemic treatment with melatonin provided additional improvements to severe periodontal condition and the glycemic control of patients with diabetes type 2 when compared to non-surgical periodontal treatment alone.

2017 ◽  
Vol 25 (4) ◽  
pp. 443-449
Author(s):  
Claudia Camila Peruzzo Lopes ◽  
Priscila do Monte Ribeiro Busato ◽  
Maira Fernanda Michelin Mânica ◽  
Marcela Chiquetto de Araújo ◽  
Muriel Machado Marquez Zampiva ◽  
...  

2021 ◽  
pp. 58-60
Author(s):  
Gargi Sharma ◽  
Priyanka Singh ◽  
Guljot singh

Objectives:The objective was to find out Correlation between the clinical (periodontal indices) and metabolic changes (glycated hemoglobin) following non-surgical periodontal treatment (pre and post),in diabetic (Type 2) patients. Material and methods: Forty type 2 diabetic patients with generalized chronic periodontitis were selected. Subjects were randomly assigned into two groups. Data collection: st rd Periodontal indices [Plaque index (PI), gingival index (GI)], were recorded at baseline, 1 and 3 st rd months. glycated hemoglobin (HbA1c), was analyzed at baseline, 1 and 3 months following the non surgical periodontal therapy. The treatment group received scaling and root planning whereas the control group received no periodontal treatment. Results:The results showed significant Correlation between periodontal indices and,levels of HbA in Type 2 diabetes 1c mellitus patients. Summary and conclusions: Non surgical periodontal therapy is associated with improved glycemic control in Type 2 diabetes mellitus patients.


2018 ◽  
Vol 5 (2) ◽  
pp. 185-192
Author(s):  
Sumaia Sahrin ◽  
Dilruba Easmin Jharna ◽  
M Shafiqul Islam Khan ◽  
Jayati Debnath ◽  
Suman Talukder

Diabetic patients with associated dyslipidemia are easy targets for cardiovascular diseases (CVD). Glycated hemoglobin predicts the risk for the development of diabetic complications. This study was an attempt to determine lipid abnormalities associated with Type-2 Diabetes Mellitus and association between glycated hemoglobin (HbA1c) levels and serum lipid profile to assess the importance of HbA1c as an indicator of dyslipidemia and future risk of cardiovascular disease in Bhola District, Barisal. In this cross-sectional study, 200 known patients of Type-2 Diabetes Mellitus within 35-85 years of age were randomly selected. They were investigated for HbA1c and lipid profile. The data were evaluated by Statistical Package for Social Sciences (SPSS) 16.0 version software. Independent samples t-test (2-tailed) was used to compare means of anthropometric, clinical and laboratory parameters and the effect of the glycemic control on their lipid profile was determined using correlation coefficient. Amongst the study group, 65% patients showed poor glycemic control, 35% with good glycemic control and 59.60% patient’s haddyslipidemia.HbA1c was found to have significant positive correlation with total cholesterol (TCHO), low density lipoprotein (LDL-C) and triglycerides (TG) and significant negative correlation with high density lipoprotein (HDL-C). The mean value of TC, LDL-C and TG was found to be lower in patients with good glycemic control than those with poor glycemic control. These differences were significant at the level of P<0.05. These findings conclude that the glycemic control of the patient has got a strong impact on the serum lipid level and dyslipidemia is frequently encountered in those who have got poor glycemic control.Res. Agric., Livest. Fish.5(2): 185-192, August 2018


2021 ◽  
Vol 27 (4) ◽  
pp. 131-136
Author(s):  
Muhammad Jawad Hashim ◽  
Halla Mustafa

<b><i>Objectives:</i></b> Lifestyle factors such as nutrition and physical activity play an important role in the management of diabetes mellitus. Unfortunately, adherence to lifestyle change remains low among patients with diabetes. The aim of this study was to evaluate the effectiveness of the Diabetes Score questionnaire in a clinical setting. <b><i>Methods:</i></b> The Diabetes Score is a 10-item shared decision-making tool designed to empower lifestyle change in individuals with diabetes. It yields an intuitive score from 0 to 100 based on a patient’s adherence to lifestyle recommendations. An observational study was conducted at an ambulatory health care center. After obtaining written informed consent, adult patients with type 2 diabetes mellitus were interviewed by a trained researcher using the Diabetes Score questionnaire. Patients’ Diabetes Score values were analyzed in reference to their glycemic control and other clinical and demographic factors. <b><i>Results:</i></b> A total of 60 individuals with type 2 diabetes participated in the study. The mean age was 56 years (minimum 43 years, maximum 70 years) with 60% being males. Higher Diabetes Scores correlated with better glycemic control (hemoglobin A1C; <i>r</i> = −0.23, <i>p</i> = 0.044) indicating the effect of lifestyle factors such as healthy nutrition, smaller portion sizes, active lifestyle, and aerobic exercise. The questionnaire showed internal consistency (alpha 0.66), construct validity, and high patient satisfaction (98%). <b><i>Conclusion:</i></b> Diabetes Score, a behavioral lifestyle questionnaire, correlates with glycemic control in type 2 diabetes. Diabetes Score can be used in clinical settings for measuring, discussing, and setting targets for lifestyle change among patients with diabetes.


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