scholarly journals Glycated haemoglobin acts as an indicator of dislipidemia in patients with Type II diabetes mellitus

2018 ◽  
Vol 5 (2) ◽  
pp. 185-192
Author(s):  
Sumaia Sahrin ◽  
Dilruba Easmin Jharna ◽  
M Shafiqul Islam Khan ◽  
Jayati Debnath ◽  
Suman Talukder
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Glycated Hemoglobin ◽  
Density Lipoprotein ◽  
Good Glycemic Control

Diabetic patients with associated dyslipidemia are easy targets for cardiovascular diseases (CVD). Glycated hemoglobin predicts the risk for the development of diabetic complications. This study was an attempt to determine lipid abnormalities associated with Type-2 Diabetes Mellitus and association between glycated hemoglobin (HbA1c) levels and serum lipid profile to assess the importance of HbA1c as an indicator of dyslipidemia and future risk of cardiovascular disease in Bhola District, Barisal. In this cross-sectional study, 200 known patients of Type-2 Diabetes Mellitus within 35-85 years of age were randomly selected. They were investigated for HbA1c and lipid profile. The data were evaluated by Statistical Package for Social Sciences (SPSS) 16.0 version software. Independent samples t-test (2-tailed) was used to compare means of anthropometric, clinical and laboratory parameters and the effect of the glycemic control on their lipid profile was determined using correlation coefficient. Amongst the study group, 65% patients showed poor glycemic control, 35% with good glycemic control and 59.60% patient’s haddyslipidemia.HbA1c was found to have significant positive correlation with total cholesterol (TCHO), low density lipoprotein (LDL-C) and triglycerides (TG) and significant negative correlation with high density lipoprotein (HDL-C). The mean value of TC, LDL-C and TG was found to be lower in patients with good glycemic control than those with poor glycemic control. These differences were significant at the level of P<0.05. These findings conclude that the glycemic control of the patient has got a strong impact on the serum lipid level and dyslipidemia is frequently encountered in those who have got poor glycemic control.Res. Agric., Livest. Fish.5(2): 185-192, August 2018

scholarly journals Study of serum lipid profile in type 2 diabetes mellitus patients and its association with diabetic nephropathy

2017 ◽  
Vol 4 (6) ◽  
pp. 1513 ◽  
Author(s):  
Ullasini Kolhar ◽  
Priyanka P.
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Diabetic Nephropathy ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Density Lipoprotein ◽  
Serum Lipid Profile ◽  
Lipid Lowering

Background: Dyslipidaemia is highly prevalent in type 2 Diabetes mellitus patients. The role of dyslipidaemia in macrovascular complications of Diabetes have been extensively studied but its role in microvascular complications namely nephropathy is still unclear. The present study was undertaken to study the prevalence and pattern of dyslipidaemia and its association with Diabetic nephropathy (DN) in patients with type 2 DM.Methods: 100 patients with type 2 DM attending OPD or admitted, over a period of 1 year were studied. Detailed history was taken and clinical examination was done. Serum lipid profile was studied in all patients and its association with DN was assessed.Results: The prevalence of dyslipidaemia in DM patients in our study was 90% and there was no statistically significant difference in the prevalence among males and females. Poorly controlled diabetics had high prevalence of dyslipidaemia as compared to well controlled diabetics. The prevalence of Diabetic nephropathy in our study was 41%. There was significant association of DN with high Total Cholesterol, high Low-density lipoprotein (LDL-C) and high Triglycerides. There was no significant association of DN with High density lipoprotein (HDL-C).Conclusions: Present study highlights the magnitude of dyslipidaemia in type2 DM patients and that there is a significant association of DN with lipid parameters. Hence patients should be managed with life style modifications with or without lipid lowering agents to achieve target lipid values along with adequate glycemic control to prevent or delay the appearance and progression of DN.

scholarly journals The Relation between Lipid Profile and Glycemic Control in Type 2 Diabetes Mellitus Patients in North Sumatera, Indonesia

2020 ◽  
Vol 8 (B) ◽  
pp. 887-891
Author(s):  
Rusdiana Rusdiana ◽  
Sry Suryani Widjaja ◽  
Maya Savira
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
High Density Lipoprotein ◽  
Lipid Profile ◽  
Density Lipoprotein ◽  
High Density ◽  
Type 2 Dm

BACKGROUND: The global prevalence of type 2 diabetes mellitus (DM), a chronic metabolic disorder, has been steadily increasing. Increasing blood sugar levels (BSL) are reliably measured by glycated hemoglobin (HbA1c). AIM: The aim of this research is to observe the relation between lipid profile with glycemic control at uncontrolled and controlled type 2 DM, early detection of abnormalities in the lipid profile can minimize cardiovascular complication risk in patients with type 2 DM. METHODS: Collecting medical data record, for example, blood pressure, height and body mass index, duration of disease, family history, and medicine treatment. Laboratory examination such as BSL, HbA1c levels, and lipid profile such as cholesterol, low-density lipoprotein, high-density lipoprotein, and triglycerides (TGs) was evaluated. The study was conducted by implementing cross-sectional methods, among 112 patients with type 2 DM who were admitted from various primary health-care centers in Medan city and the surrounding areas in North Sumatera. The sample criteria are type 2 DM’ patients and both genders. The exclusion criteria of the samples are those with type 1 DM and critical disease. RESULTS: There is a difference between the average lipid profile level (high-density lipoprotein and TG) in controlled and uncontrolled type 2 DM. Furthermore, there is also a difference between the average HbA1c value in controlled type 2 DM and uncontrolled type 2 DM (p<0.005). CONCLUSION: This study showed a difference in lipid profile (high-density lipoprotein and TG) and HbA1c between uncontrolled and controlled type 2 DM. Therefore, type 2 DM patients were recommended to undergo periodical glycemic and lipid profile examination control to prevent cardiovascular disease complication.

scholarly journals Serum lipid profile in native populations (evens, nanais, ulchis) of the Amur region diagnosed with type 2 diabetes mellitus

2011 ◽  
Vol 14 (2) ◽  
pp. 6-8
Author(s):  
Tatiana Ivanovna Ryabova ◽  
Boris Zalmanovich Sirotin
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Density Lipoprotein ◽  
Amur Region ◽  
Serum Lipid Profile ◽  
Native Populations

Aim. To determine serum lipid profile in native populations (Evens, Nanais, Ulchis) of the Amur region diagnosed with type 2 diabetes mellitus. Materials and methods. 297 Evens, 792 Ulchis, and 1,274 Nanais aged 30-70 years and older were examined. Total cholesterol, triglyceride, andhigh-density lipoprotein were measured with a Sapphire autoanalyzer (Japan) using Olveks Diagnosticim enzymatic kits (including reference sera).LDL levels were calculated by W.Fridewold formula (TC-HDL-TG/2.2) in millimol/l. Glucose tolerance test to verify type 2 DM was performed withthe measurement of blood glucose level by the glucose oxidase method. Previously diagnosed DM2 was taken into account. The results were estimatedbased on WHO criteria (1999). The study was carried out in winter time. Conclusion. Changes of the serum lipid profile in DM2 female aborigines of the Amur region were consistent with the literature data. Specifically, theyshow higher TC, TG,, HDL and lower LDL levels compared with DM-free women of the same population. The lowest levels of TC, TG, HDL, andLDL were documented in female Evens. Nanais and Ulchis with DM2 had similar lipid profiles.

Benefits of micronised Fenofibrate in type 2 diabetes mellitus subjects with good glycemic control

2001 ◽  
Vol 154 (2) ◽  
pp. 469-474 ◽  
Author(s):  
C.E. Tan ◽  
L.S. Chew ◽  
E.S. Tai ◽  
L.F. Chio ◽  
H.S. Lim ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Good Glycemic Control
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