scholarly journals Bartonella alsatica in Wild and Domestic Rabbits (Oryctolagus cuniculus) in The Netherlands

2021 ◽  
Vol 12 (2) ◽  
pp. 524-527
Author(s):  
Marja J. L. Kik ◽  
Ryanne I. Jaarsma ◽  
Jooske IJzer ◽  
Hein Sprong ◽  
Andrea Gröne ◽  
...  

Members of the genus Bartonella are Gram-negative facultative intracellular bacteria that are transmitted by arthropod vectors. Bartonella alsatica was detected in the spleens and livers of 7 out of 56 wild rabbits (Oryctolagus cuniculus) and in the liver of 1 out of 87 domestic rabbits in the Netherlands. The molecular evidence of B. alsatica infection in wild as well as domestic rabbits indicates the possibility of exposure to humans when these come in close contact with rabbits and possibly their fleas with subsequent risk of Bartonella infection and disease.

2021 ◽  
Vol 28 (1) ◽  
pp. 41-61
Author(s):  
Monika Glimskär ◽  
Helena Backman

Abstract The De Geer family established themselves in Sweden as iron industrialists during the early seventeenth century, but they maintained close contact with the Netherlands. The family built up a prestigious library at Leufstabruk, in northern Uppland. The objects in the Leufsta Music Collection contained a significant amount of music in the form of printed sheet music and manuscripts, which were most likely gathered during the long lifetime of baron Charles De Geer (1720-1778). Compared to the works he collected in his youth in the Netherlands, the printed scores linked to Charles De Geer’s later period in Sweden show a change of taste in both repertoire and collecting behavior. This article deals with the bindings of the sheet music in the Leufsta collection, which give us clues of both De Geer’s acquisition and his approach to his music scores from their purchase to binding, labelling, cataloguing and practical use.


Ethology ◽  
2010 ◽  
Vol 103 (11) ◽  
pp. 893-901 ◽  
Author(s):  
Margarita Martínez-Gómez ◽  
Madai Guarneros ◽  
René Zempoalteca ◽  
Robyn Hudson

Viruses ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 553 ◽  
Author(s):  
Qiuhong Miao ◽  
Ruibing Qi ◽  
Luut Veldkamp ◽  
Jooske Ijzer ◽  
Marja L. Kik ◽  
...  

Rabbit haemorrhagic disease virus (RHDV) type 2 (GI.2/RHDV2/b) is an emerging pathogen in wild rabbits and in domestic rabbits vaccinated against RHDV (GI.1). Here we report the genome sequence of a contemporary RHDV2 isolate from the Netherlands and investigate the immunogenicity of virus-like particles (VLPs) produced in insect cells. RHDV2 RNA was isolated from the liver of a naturally infected wild rabbit and the complete viral genome sequence was assembled from sequenced RT-PCR products. Phylogenetic analysis based on the VP60 capsid gene demonstrated that the RHDV2 NL2016 isolate clustered with other contemporary RHDV2 strains. The VP60 gene was cloned in a baculovirus expression vector to produce VLPs in Sf9 insect cells. Density-gradient purified RHDV2 VLPs were visualized by transmission electron microscopy as spherical particles of around 30 nm in diameter with a morphology resembling authentic RHDV. Immunization of rabbits with RHDV2 VLPs resulted in high production of serum antibodies against VP60, and the production of cytokines (IFN-γ and IL-4) was significantly elevated in the immunized rabbits compared to the control group. The results demonstrate that the recombinant RHDV2 VLPs are highly immunogenic and may find applications in serological detection assays and might be further developed as a vaccine candidate to protect domestic rabbits against RHDV2 infection.


Teratology ◽  
1976 ◽  
Vol 13 (3) ◽  
pp. 243-251 ◽  
Author(s):  
R. R. Fox ◽  
S. H. Weisbroth ◽  
D. D. Crary ◽  
S. Scher

2014 ◽  
Vol 26 (5) ◽  
pp. 689-694 ◽  
Author(s):  
Ricardo de Matos ◽  
Duncan Russell ◽  
William Van Alstine ◽  
Andrew Miller

Nature ◽  
1963 ◽  
Vol 200 (4909) ◽  
pp. 858-860 ◽  
Author(s):  
E. SHIPP ◽  
K. KEITH ◽  
R. L. HUGHES ◽  
K. MYERS

2004 ◽  
Vol 135 (1) ◽  
pp. 100-107 ◽  
Author(s):  
Christian C Voigt ◽  
Mirja Faßbender ◽  
Martin Dehnhard ◽  
Gudrun Wibbelt ◽  
Katarina Jewgenow ◽  
...  

2017 ◽  
Vol 26 (1) ◽  
pp. 57-62 ◽  
Author(s):  
Michelle Sutherland ◽  
Christine T. Higbie ◽  
Nicholas A. Crossland ◽  
Filipe Espinheira ◽  
Dawn Evans ◽  
...  

2021 ◽  
Vol 8 ◽  
Author(s):  
Jun Ni ◽  
Qiaoyun Ren ◽  
Hanliang Lin ◽  
Malike Aizezi ◽  
Jin Luo ◽  
...  

Bartonella are gram-negative intracellular bacteria; certain species of Bartonella can cause diseases in mammals and humans. Ticks play a major role in the transmission of Bartonella. Xinjiang is the largest province in China according to land area and has one-third of the tick species in China; the infection rate of Bartonella in ticks in the Xinjiang border areas has not been studied in detail. Therefore, this study investigated tick infections by Bartonella in Xinjiang border areas, and the purpose of the study was to fill in gaps in information regarding the genetic diversity of tick infections by Bartonella in Xinjiang. We tested 1,549 tick samples from domestic animals (sheep and cattle) for Bartonella using ribC-PCR. Positive samples from the ribC-PCR assay for Bartonella spp. were further subjected to PCR assays targeting the ITS, rpoB and gltA genes followed by phylogenetic analyses. Bartonella DNA was detected in 2.19% (34/1,549) of tick samples, and the ITS, rpoB and gltA genes of ribC gene-positive samples were amplified to identify nine samples of Bartonella melophagi. In this study, molecular analysis was used to assess the presence and genetic diversity of B. melophagi in ticks collected from sheep and cattle from Xinjiang, China. This study provides new information on the presence and identity of B. melophagi in ticks from sheep and cattle.


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