Evodiamine Stabilizes Topoisomerase I-DNA Cleavable Complex to Inhibit Topoisomerase I Activity

Molecules ◽

10.3390/molecules14041342 ◽

2009 ◽

Vol 14 (4) ◽

pp. 1342-1352 ◽

Author(s):

Agnes Chan ◽

Wen-Shin Chang ◽

Li-Min Chen ◽

Chi-Ming Lee ◽

Chiao-En Chen ◽

...

Keyword(s):

Topoisomerase I ◽

Cleavable Complex

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Immobilizing Topoisomerase I on a Surface Plasmon Resonance Biosensor Chip to Screen for Top1-DNA Cleavable Complex Inhibitors

Free Radical Biology and Medicine ◽

10.1016/j.freeradbiomed.2010.10.584 ◽

2010 ◽

Vol 49 ◽

pp. S201-S202

Author(s):

Hsiang Ping Tsai ◽

Jaulang Hwang ◽

Chun Mao Lin

Keyword(s):

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Topoisomerase I ◽

Surface Plasmon Resonance Biosensor ◽

Biosensor Chip ◽

Cleavable Complex

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SUMO-1 conjugation to intact DNA topoisomerase I amplifies cleavable complex formation induced by camptothecin

Oncogene ◽

10.1038/sj.onc.1205917 ◽

2002 ◽

Vol 21 (52) ◽

pp. 7913-7922 ◽

Author(s):

Koji Horie ◽

Akihiro Tomida ◽

Yoshikazu Sugimoto ◽

Toshiharu Yasugi ◽

Hiroyuki Yoshikawa ◽

...

Keyword(s):

Complex Formation ◽

Topoisomerase I ◽

Dna Topoisomerase I ◽

Dna Topoisomerase ◽

Cleavable Complex

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Molecular Modeling Studies of the DNA−Topoisomerase I Ternary Cleavable Complex with Camptothecin

Journal of Medicinal Chemistry ◽

10.1021/jm9605445 ◽

1998 ◽

Vol 41 (13) ◽

pp. 2216-2226 ◽

Author(s):

Y. Fan ◽

J. N. Weinstein ◽

K. W. Kohn ◽

L. M. Shi ◽

Y. Pommier

Keyword(s):

Molecular Modeling ◽

Topoisomerase I ◽

Dna Topoisomerase I ◽

Dna Topoisomerase ◽

Modeling Studies ◽

Molecular Modeling Studies ◽

Cleavable Complex

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A Structural Model for the Ternary Cleavable Complex Formed between Human Topoisomerase I, DNA, and Camptothecin†

Biochemistry ◽

10.1021/bi010913l ◽

2001 ◽

Vol 40 (33) ◽

pp. 9792-9798 ◽

Author(s):

John E. Kerrigan ◽

Daniel S. Pilch

Keyword(s):

Topoisomerase I ◽

Structural Model ◽

Cleavable Complex

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Effect of CPT on the calf thymus Topoisomerase I-mediated DNA breakage-reunion reaction: Optimal conditions for the formation and reversal of the CPT trapped Topoisomerase I cleavable complex

Molecular Biology Reports ◽

10.1007/bf00996220 ◽

1993 ◽

Vol 17 (2) ◽

pp. 129-134 ◽

Author(s):

S. Coderoni ◽

M. Paparelli ◽

G. L. Gianfranceschi

Keyword(s):

Topoisomerase I ◽

Optimal Conditions ◽

Dna Breakage ◽

Calf Thymus ◽

Cleavable Complex

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Zinc (II) coordination in Escherichia coli DNA topoisomerase I is required for cleavable complex formation with DNA

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)98686-2 ◽

1991 ◽

Vol 266 (22) ◽

pp. 14317-14320

Author(s):

Y.C. Tse-Dinh

Keyword(s):

Escherichia Coli ◽

Complex Formation ◽

Topoisomerase I ◽

Dna Topoisomerase I ◽

Dna Topoisomerase ◽

Cleavable Complex

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AK37: the first pyridoacridine described capable of stabilizing the topoisomerase I cleavable complex

Anti-Cancer Drugs ◽

10.1097/00001813-200410000-00012 ◽

2004 ◽

Vol 15 (9) ◽

pp. 907-913 ◽

Author(s):

Kathryn M. Marshall ◽

Joseph A. Holden ◽

Avi Koller ◽

Yoel Kashman ◽

Brent R. Copp ◽

...

Keyword(s):

Topoisomerase I ◽

Cleavable Complex

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Betulinic Acid, a Catalytic Inhibitor of Topoisomerase I, Inhibits Reactive Oxygen Species Mediated Apoptotic Topoisomerase I DNA Cleavable Complex Formation in Prostate Cancer Cells but Does Not Affect the Process of Cell Death

Cancer Research ◽

10.1158/0008-5472.can-07-1615 ◽

2007 ◽

Vol 67 (24) ◽

pp. 11848-11858 ◽

Author(s):

A. Ganguly ◽

B. Das ◽

A. Roy ◽

N. Sen ◽

S. B. Dasgupta ◽

...

Keyword(s):

Prostate Cancer ◽

Reactive Oxygen Species ◽

Complex Formation ◽

Cancer Cells ◽

Topoisomerase I ◽

Oxygen Species ◽

Prostate Cancer Cells ◽

Catalytic Inhibitor ◽

Cleavable Complex

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Binding mode analysis of topoisomerase inhibitors, 6-arylamino-7-chloro-quinazoline-5,8-diones, within the cleavable complex of human topoisomerase I and DNA

Archives of Pharmacal Research ◽

10.1007/bf02977321 ◽

2007 ◽

Vol 30 (12) ◽

pp. 1526-1535 ◽

Author(s):

Inhee Choi ◽

Choonmi Kim ◽

Sun Choi

Keyword(s):

Topoisomerase I ◽

Binding Mode ◽

Mode Analysis ◽

Topoisomerase Inhibitors ◽

Cleavable Complex

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Correlation between the Formation of Cleavable Complex with Topoisomerase I and Growth-Inhibitory Activity for Saintopin-Type Antibiotics

Molecular Pharmacology ◽

10.1124/mol.51.2.269 ◽

1997 ◽

Vol 51 (2) ◽

pp. 269-276 ◽

Author(s):

Noboru Fujii ◽

Yoshinori Yamashita ◽

Tamio Mizukami ◽

Hirofumi Nakano

Keyword(s):

Inhibitory Activity ◽

Topoisomerase I ◽

Growth Inhibitory ◽

Growth Inhibitory Activity ◽

Cleavable Complex

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