scholarly journals Optimized and Automated Radiosynthesis of [18F]DHMT for Translational Imaging of Reactive Oxygen Species with Positron Emission Tomography

Molecules ◽  
2016 ◽  
Vol 21 (12) ◽  
pp. 1696 ◽  
Author(s):  
Wenjie Zhang ◽  
Zhengxin Cai ◽  
Lin Li ◽  
Jim Ropchan ◽  
Keunpoong Lim ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Positron Emission Tomography ◽  
Reactive Oxygen ◽  
Emission Tomography ◽  
Oxygen Species ◽  
Automated Radiosynthesis ◽  
Positron Emission ◽  
Translational Imaging

scholarly journals [11C]Ascorbic and [11C]dehydroascorbic acid, an endogenous redox pair for sensing reactive oxygen species using positron emission tomography

2016 ◽  
Vol 52 (27) ◽  
pp. 4888-4890 ◽  
Author(s):  
V. N. Carroll ◽  
C. Truillet ◽  
B. Shen ◽  
R. R. Flavell ◽  
X. Shao ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Positron Emission Tomography ◽  
Ascorbic Acid ◽  
Reactive Oxygen ◽  
Dehydroascorbic Acid ◽  
Emission Tomography ◽  
Oxygen Species ◽  
Redox Pair ◽  
Positron Emission

We report the radiosynthesis of an endogenous redox pair, [11C]ascorbic acid and [11C]dehydroascorbic acid and their application to ROS sensing.

18F-Labeled dihydromethidine: positron emission tomography radiotracer for imaging of reactive oxygen species in intact brain

2020 ◽  
Vol 18 (13) ◽  
pp. 2387-2391 ◽  
Author(s):  
Hiromichi Egami ◽  
Satoshi Nakagawa ◽  
Yuki Katsura ◽  
Masakatsu Kanazawa ◽  
Shingo Nishiyama ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Positron Emission Tomography ◽  
Benzene Ring ◽  
Reactive Oxygen ◽  
Emission Tomography ◽  
Oxygen Species ◽  
Non Invasive ◽  
Positron Emission ◽  
Intact Brain ◽  
Positron Emission Tomography Radiotracer

Dihydromethidine (DHM) labeled with 18F at the para position of the benzene ring has been developed as a positron emission tomography (PET) radiotracer for non-invasive imaging of reactive oxygen species (ROS).

A report of the automated radiosynthesis of the tau positron emission tomography radiopharmaceutical, [18F]-THK-5351

2017 ◽  
Vol 60 (2) ◽  
pp. 140-146 ◽  
Author(s):  
Ramesh Neelamegam ◽  
Daniel L. Yokell ◽  
Peter A. Rice ◽  
Shozo Furumoto ◽  
Yukitsuka Kudo ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Emission Tomography ◽  
Automated Radiosynthesis ◽  
Positron Emission

scholarly journals Automated radiosynthesis of [11 C]UCB-J for imaging synaptic density by positron emission tomography

2020 ◽  
Vol 63 (3) ◽  
pp. 151-158 ◽  
Author(s):  
Selena Milicevic Sephton ◽  
Tunde Miklovicz ◽  
Joseph J. Russell ◽  
Aniruddha Doke ◽  
Lei Li ◽  
...  
Keyword(s):  
Positron Emission Tomography ◽  
Emission Tomography ◽  
Synaptic Density ◽  
Automated Radiosynthesis ◽  
Positron Emission

An improved automated radiosynthesis of [18F]FET-βAG-TOCA

2019 ◽  
Vol 4 (3) ◽  
pp. 569-574 ◽  
Author(s):  
Louis Allott ◽  
Chris Barnes ◽  
Diana Brickute ◽  
Eric O. Aboagye
Keyword(s):  
Positron Emission Tomography ◽  
Click Chemistry ◽  
Pet Imaging ◽  
Neuroendocrine Tumours ◽  
Emission Tomography ◽  
Prosthetic Group ◽  
Automated Radiosynthesis ◽  
Positron Emission

The fluorine-18 radiolabelled octreotide [18F]FET-βAG-TOCA has been evaluated clinically for positron emission tomography (PET) imaging of neuroendocrine tumours (NETs). An improved automated radiosynthesis using “click” chemistry (CuAAC) and the 2-[18F]fluoroethylazide prosthetic group is reported and with minimal adaptation, may be used for radiolabelling other peptides.

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