scholarly journals New Azaphilones from Nigrospora oryzae Co-Cultured with Beauveria bassiana

Molecules ◽  
2018 ◽  
Vol 23 (7) ◽  
pp. 1816 ◽  
Author(s):  
Zhuo-Xi Zhang ◽  
Xue-Qiong Yang ◽  
Qing-Yan Zhou ◽  
Bang-Yan Wang ◽  
Ming Hu ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Spectral Analysis ◽  
Beauveria Bassiana ◽  
Inhibitory Activity ◽  
Competitive Interaction ◽  
Dendrobium Officinale ◽  
Oxygen Bridge ◽  
Metabolite Diversity ◽  
Nigrospora Oryzae

In this study, the co-culture of Nigrospora oryzae and Beauveria bassiana, the endophytes in the seeds of Dendrobium officinale, were examined for metabolite diversity. Five new azaphilones were isolated, and their structures were determined by spectral analysis. In terms of azaphilones, compound 2 had an unprecedented skeleton, with a bicyclic oxygen bridge. The antifungal selectivities of the metabolite produced by N. oryzae against its co-culture fungus, B. bassiana, and common pathogens exhibited competitive interaction in this mix-culture. Compounds 1 and 2 showed obvious nitric oxide (NO) inhibitory activity with ratios of 37%, and 39%, respectively, at a concentration of 50 μM.

A New Chlorinated Tetralone from Co-Culture of Insect-Pathogenic Beauveria bassiana and Phytopathogenic Nigrospora oryzae

2021 ◽  
Vol 57 (2) ◽  
pp. 297-299
Author(s):  
Zhuo-Xi Zhang ◽  
Hai-Yue Yin ◽  
Ya-Bin Yang ◽  
Dai-Li Wang ◽  
Tong-De Zhao ◽  
...  
Keyword(s):  
Beauveria Bassiana ◽  
Nigrospora Oryzae

Nitric oxide production inhibitory activity of clerodane diterpenes from Monoon membranifolium

2021 ◽  
pp. 1-5
Author(s):  
Isaraporn Polbuppha ◽  
Virayu Suthiphasilp ◽  
Tharakorn Maneerat ◽  
Rawiwan Charoensup ◽  
Thunwadee Limtharakul ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Inhibitory Activity ◽  
Nitric Oxide Production ◽  
Oxide Production ◽  
Clerodane Diterpenes

Nitric Oxide Inhibitory Activity and Absolute Configurations of Arylalkenyl α,β-Unsaturated δ/γ-Lactones from Cryptocarya concinna

2016 ◽  
Vol 79 (1) ◽  
pp. 196-203 ◽  
Author(s):  
Bing-Yuan Yang ◽  
Ling-Yi Kong ◽  
Xiao-Bing Wang ◽  
Yang-Mei Zhang ◽  
Rui-Jun Li ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Inhibitory Activity ◽  
Cryptocarya Concinna

Diarylheptanoids with In Vitro Inducible Nitric Oxide Synthesis Inhibitory Activity from Alnus hirsuta

Planta Medica ◽  
2000 ◽  
Vol 66 (6) ◽  
pp. 551-553 ◽  
Author(s):  
Min-Won Lee ◽  
Na-Young Kim ◽  
Myung-Shin Park ◽  
Kyoung-Hwan Ahn ◽  
Sang-Hak Toh ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Inhibitory Activity ◽  
Nitric Oxide Synthesis ◽  
Alnus Hirsuta ◽  
Inducible Nitric Oxide

Cadinane sesquiterpenoids from the fungus Antrodiella albocinnamomea and their inhibitory activity against nitric oxide production

2022 ◽  
Vol 196 ◽  
pp. 113081
Author(s):  
Wei-Wei Yu ◽  
Jin-Tao Ma ◽  
Juan He ◽  
Zheng-Hui Li ◽  
Ji-Kai Liu ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Inhibitory Activity ◽  
Nitric Oxide Production ◽  
Oxide Production

scholarly journals Diarylheptanoids of Curcuma comosa with Inhibitory Effects on Nitric Oxide Production in Macrophage RAW 264.7 Cells

2015 ◽  
Vol 10 (1) ◽  
pp. 1934578X1501000 ◽  
Author(s):  
Nilubon Sornkaew ◽  
Yuan Lin ◽  
Fei Wang ◽  
Guolin Zhang ◽  
Ratchanaporn Chokchaisiri ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Inhibitory Activity ◽  
Raw 264.7 Cells ◽  
Racemic Mixture ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Inhibitory Effects ◽  
Curcuma Comosa ◽  
Oxide Production ◽  
Potent Inhibitory Activity

Eight new diarylheptanoids, a 1.2:1 mixture of (3S)- and (3 R)-1-(4-hydroxyphenyl)-7-phenyl-(4 E,6 E)-4,6-heptadien-3-ol (1a and 1b), a racemic mixture of (3S)- and (3 R)-1-(4-hydroxyphenyl)-3-methoxy-7-phenyl-(4 E,6 E)-4,6-heptadiene (2a and 2b), a ca. 1:1 mixture of (3S)- and (3 R)-1-(4-hydroxy-3-methoxyphenyl)-3-methoxy-7-phenyl)-(4 E,6 E)-4,6-heptadiene (3a and 3b), 3-acetoxy-1-(3,4-dihydroxyphenyl)-7-phenylheptan-5-ol (4), (3 R)-1-(4,5-dihydroxyphenyl)-7-phenyl-(6 E)-6-hepten-3,2′-epoxide (5), and thirteen known diarylheptanoids, 6-12, a 3:1 mixture of 13a and 13b, and 14-17, were isolated from the rhizomes of Curcuma comosa from Sakon Nakhon, northeastern part of Thailand. The isolated compounds were evaluated for their antiinflammatory activities on the inhibition of lipopolysaccharide-induced nitric oxide production in macrophage RAW 264.7 cells and the diarylheptanoids 1a and 1b mixture and 14 exhibited potent inhibitory activity.

scholarly journals Flavonoids from Anoectochilus annamensis and their Anti-inflammatory Activity

2016 ◽  
Vol 11 (5) ◽  
pp. 1934578X1601100 ◽  
Author(s):  
Tran Minh Hoi ◽  
Tran Van Thai ◽  
Chu Thi Thu Ha ◽  
Ha Thi Van Anh ◽  
Phan Xuan Binh Minh ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Biological Activity ◽  
Chemical Composition ◽  
Inhibitory Activity ◽  
Inflammatory Mediator ◽  
Methanol Extract ◽  
Inflammatory Activity ◽  
Raw264.7 Cells ◽  
First Report ◽  
Aerial Parts

One new flavonol diglycoside, 4′,5-dihydroxy-3,3′,7-trimethoxyflavone 4′- O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (1), and two known compounds (2–3) were isolated from the methanol extract of Anoectochilus annamensis Aver. aerial parts. The effects were evaluated of all isolated compounds (1–3) on LPS-induced production of the inflammatory mediator nitric oxide (NO) by RAW264.7 cells. 4′,5-Dihydroxy-3,3′,7-trimethoxyflavone (2) was the most active while the addition of a rutinoside at C-4′ (compound 1) decreased the inhibitory activity. This is the first report on the chemical composition and biological activity of A annamensis.

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