scholarly journals Magnetic Nanomaterials for Arterial Embolization and Hyperthermia of Parenchymal Organs Tumors: A Review

Nanomaterials ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3402
Author(s):  
Natalia E. Kazantseva ◽  
Ilona S. Smolkova ◽  
Vladimir Babayan ◽  
Jarmila Vilčáková ◽  
Petr Smolka ◽  
...  
Keyword(s):  
Magnetic Particles ◽  
Thermal Destruction ◽  
Vascular System ◽  
Arterial Embolization ◽  
Double Effect ◽  
Magnetic Hyperthermia ◽  
Magnetic Nanomaterials ◽  
Invasive Treatment ◽  
Embolic Agents ◽  
Oncological Diseases

Magnetic hyperthermia (MH), proposed by R. K. Gilchrist in the middle of the last century as local hyperthermia, has nowadays become a recognized method for minimally invasive treatment of oncological diseases in combination with chemotherapy (ChT) and radiotherapy (RT). One type of MH is arterial embolization hyperthermia (AEH), intended for the presurgical treatment of primary inoperable and metastasized solid tumors of parenchymal organs. This method is based on hyperthermia after transcatheter arterial embolization of the tumor's vascular system with a mixture of magnetic particles and embolic agents. An important advantage of AEH lies in the double effect of embolotherapy, which blocks blood flow in the tumor, and MH, which eradicates cancer cells. Consequently, only the tumor undergoes thermal destruction. This review introduces the progress in the development of polymeric magnetic materials for application in AEH.

scholarly journals Electroactive Composites with Block Copolymer-Templated Iron Oxide Nanoparticles for Magnetic Hyperthermia Application

Polymers ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 1430
Author(s):  
Shu-Chian Yang ◽  
Chun-Yu Chen ◽  
Hung-Yu Wan ◽  
Szu-Ying Huang ◽  
Ta-I Yang
Keyword(s):  
Iron Oxide ◽  
Block Copolymer ◽  
Magnetic Particles ◽  
Magnetic Hyperthermia ◽  
Promising Technique ◽  
Cathodic Current ◽  
Heating Performance ◽  
Relaxation Loss ◽  
And Control ◽  
Human Death

Cancer has been one of the leading causes of human death for centuries. Magnetic hyperthermia is a promising technique to confine and control cancers. However, particles used in magnetic hyperthermia leaking from where the cancers are located could compromise human health. Therefore, we developed electroactive iron oxide/block copolymer composites to tackle the leakage problem. Experimental results show that oleylamine-modified magnetic iron oxide (Fe3O4) particles and electroactive tetraaniline (TA) could be templated in the self-assembled microstructures of sulfonated [styrene-b-(ethylene-ran-butylene)-b-styrene] (S-SEBS) block copolymers. Various amounts of Fe3O4 particles and TA oligomer were incorporated in S-SEBS block copolymer and their electroactive behavior was confirmed by exhibiting two pairs of well-defined anodic and cathodic current peaks in cyclic voltammetry tests. The heating performance of the resultant TA/Fe3O4/polymer composites improved on increasing the added amount of Fe3O4 particles and TA oligomers. Both Fe3O4 and TA can contribute to improved heating performance, but Fe3O4 possesses a greater contribution than TA does. Hence, the main source for increasing the composites’ temperature is Neel relaxation loss from Fe3O4 magnetic particles.

Intraosseous Arteriovenous Malformations Mimicking Malignant Disease

1988 ◽  
Vol 29 (1) ◽  
pp. 109-114 ◽  
Author(s):  
S. J. Savader ◽  
B. L. Savader ◽  
R. R. Otero
Keyword(s):  
Surgical Treatment ◽  
Cardiac Failure ◽  
Arteriovenous Malformations ◽  
Malignant Disease ◽  
Vascular System ◽  
Arterial Embolization ◽  
Initial Work ◽  
Work Up ◽  
High Output

Primary (congenital) intraosseous arteriovenous malformations are rare, accounting for less than one per cent of all primary intraosseous lesions. They are quite variable in their gross and microscopic presentation, yet all can be traced to anomalous development of the primitive vascular system. They may be totally asymptomatic, cosmetically disfiguring, painful, or on rare occasions, cause high-output cardiac failure. Surgical treatment is often unrewarding with recurrence not uncommon. Intra-arterial embolization has shown promising results. We present three cases of primary intraosseous arteriovenous malformations which on initial work-up mimicked malignant disease. Arteriography proved diagnostic in all three cases.

scholarly journals Magnetic hyperthermia with Fe - Cr- Nb - B magnetic particles

2017 ◽  
Author(s):  
Iordana Astefanoaei ◽  
Alexandru Stancu ◽  
Horia Chiriac
Keyword(s):  
Magnetic Particles ◽  
Magnetic Hyperthermia

scholarly journals Effect of manganese doping on the hyperthermic profile of ferrite nanoparticles using response surface methodology

RSC Advances ◽  
2021 ◽  
Vol 11 (28) ◽  
pp. 16942-16954
Author(s):  
Ruby Gupta ◽  
Ruchi Tomar ◽  
Suvankar Chakraverty ◽  
Deepika Sharma
Keyword(s):  
Magnetic Field ◽  
Response Surface Methodology ◽  
Cancer Therapy ◽  
Response Surface ◽  
Magnetic Hyperthermia ◽  
Ferrite Nanoparticles ◽  
Alternating Magnetic Field ◽  
Magnetic Nanomaterials ◽  
Manganese Doping

Magnetic hyperthermia-based cancer therapy mediated by magnetic nanomaterials is a promising antitumoral nanotherapy, owning to its power to generate heat under the application of an alternating magnetic field.

scholarly journals The Effect of Tissue-Mimicking Phantom Compressibility on Magnetic Hyperthermia

Nanomaterials ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. 803 ◽  
Author(s):  
Katarzyna Kaczmarek ◽  
Radosław Mrówczyński ◽  
Tomasz Hornowski ◽  
Rafał Bielas ◽  
Arkadiusz Józefczak
Keyword(s):  
Magnetic Field ◽  
Electron Microscopy ◽  
Magnetic Materials ◽  
Absorption Rate ◽  
Magnetic Particles ◽  
Specific Absorption Rate ◽  
Magnetic Hyperthermia ◽  
Magnetic Losses ◽  
Small Temperature ◽  
Transmission Electron

During hyperthermia, magnetite nanoparticles placed in an AC magnetic field become a source of heat. It has been shown that in fluid suspensions, magnetic particles move freely and generate heat easily. However, in tissues of different mechanical properties, nanoparticle movement is limited and leads to a small temperature rise in tissue. Therefore, it is crucial to conduct magnetic hyperthermia experiments in similar conditions to the human body. The effect of tissue-mimicking phantom compressibility on the effectiveness of magnetic hyperthermia was investigated on agar phantoms. Single and cluster nanoparticles were synthesized and used as magnetic materials. The prepared magnetic materials were characterized by transmission electron microscopy (TEM), and zeta potential measurements. Results show that tissue-mimicking phantom compressibility decreases with the concentration of agar. Moreover, the lower the compressibility, the lower the thermal effect of magnetic hyperthermia. Specific absorption rate (SAR) values also proved our assumption that tissue-mimicking phantom compressibility affects magnetic losses in the alternating magnetic field (AMF).

scholarly journals MAGNETIC AND THERMAL PROPERTIES OF NANOMATERIALS BASED ON HIGHLY BRANCHED FERROCENE-CONTAINING POLYMERS

2018 ◽  
Vol 13 (5) ◽  
pp. 49-57 ◽  
Author(s):  
R. A. Dvorikov ◽  
V. A. Vasnev ◽  
А. А. Korlukov ◽  
М. I. Buzin
Keyword(s):  
Ir Spectroscopy ◽  
Magnetic Particles ◽  
Heating Temperature ◽  
Treatment Temperature ◽  
Magnetic Nanomaterials ◽  
X Ray Diffraction ◽  
Tem Analysis ◽  
Transmission Electron ◽  
Average Size ◽  
Principal Possibility

New magnetic nanomaterials with magnetization up to 32 Gs·cm3/g were synthesized from highly branched ferrocene-containing polymers by thermal structural transformations in a field of 2.5 kOe. The structure and properties of the prepared polymers were studied by IR spectroscopy, transmission electron microscopy (TEM) and thermogravimetric analyses. According to IR spectroscopy the content of 1,3,5-substituted benzene rings in the ferrocene-containing polymer increases at 500°C. X-ray diffraction study showed that iron in such a sample is present exclusively in the form of Fe3O4 magnetite. As the heating temperature increased to 600°C, the composition of the samples became more complex: along with magnetite they contain cementite Fe3C and wustite FeO.97O. The magnetization of the ferrocene-containing polymer depends on the synthesis and heat treatment temperature. For a sample synthesized at 140°C the formation of a magnetically ordered phase begins at 500°C, and at 800°C the magnetization reaches a maximum value of 32 Gs·cm3/g. The average size of magnetic particles according to TEM analysis was 8-26 nm. The principal possibility of controlling the size and composition of the nanoparticles, as well as their magnetization depending on the conditions of production and the temperature of polymer structuring is shown. The obtained results provide a good basis for the directed synthesis of magnetic ferrocene-containing polymers with preset characteristics.

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