scholarly journals Unravelling the Thermal Decomposition Parameters for The Synthesis of Anisotropic Iron Oxide Nanoparticles

Nanomaterials ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 881 ◽  
Author(s):  
Geoffrey Cotin ◽  
Céline Kiefer ◽  
Francis Perton ◽  
Dris Ihiawakrim ◽  
Cristina Blanco-Andujar ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Sodium Oleate ◽  
Shape Control ◽  
Oxide Nanoparticles ◽  
Chelating Ligand ◽  
Precursor Structure ◽  
Negative Effect ◽  
Magnetic Resonance Imaging Mri

Iron oxide nanoparticles are widely used as a contrast agent in magnetic resonance imaging (MRI), and may be used as therapeutic agent for magnetic hyperthermia if they display in particular high magnetic anisotropy. Considering the effect of nanoparticles shape on anisotropy, a reproducible shape control of nanoparticles is a current synthesis challenge. By investigating reaction parameters, such as the iron precursor structure, its water content, but also the amount of the surfactant (sodium oleate) reported to control the shape, iron oxide nanoparticles with different shape and composition were obtained, in particular, iron oxide nanoplates. The effect of the surfactant coming from precursor was taking into account by using in house iron stearates bearing either two or three stearate chains and the negative effect of water on shape was confirmed by considering these precursors after their dehydration. Iron stearates with three chains in presence of a ratio sodium oleate/oleic acid 1:1 led mainly to nanocubes presenting a core-shell Fe1−xO@Fe3−xO4 composition. Nanocubes with straight faces were only obtained with dehydrated precursors. Meanwhile, iron stearates with two chains led preferentially to the formation of nanoplates with a ratio sodium oleate/oleic acid 4:1. The rarely reported flat shape of the plates was confirmed with 3D transmission electronic microscopy (TEM) tomography. The investigation of the synthesis mechanisms confirmed the major role of chelating ligand and of the heating rate to drive the cubic shape of nanoparticles and showed that the nanoplate formation would depend mainly on the nucleation step and possibly on the presence of a given ratio of oleic acid and chelating ligand (oleate and/or stearate).

scholarly journals Unravelling the Thermal Decomposition Parameters for the Synthesis of Anisotropic Iron Oxide Nanoparticles

2018 ◽  
Author(s):  
Geoffrey Cotin ◽  
Celine Kiefer ◽  
Francis Perton ◽  
Dris Ihiawakrim ◽  
Cristina Blanco-Andujar ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Iron Oxide ◽  
Carboxylic Acid ◽  
Iron Oxide Nanoparticles ◽  
Sodium Oleate ◽  
Shape Control ◽  
Oxide Nanoparticles ◽  
Synthesis Methods ◽  
Surfactant Mixtures ◽  
Negative Effect

Iron oxide nanoparticles are widely used as contrast agent for MRI and may be used as therapeutic agent by magnetic hyperthermia if they display a high magnetic anisotropy. Considering the effect of the nanoparticles shape on anisotropy, the reproducible shape control of nanoparticles is currently a challenge of synthesis methods. By investigating reaction parameters which are the iron precursor structure, the water content and the amount of the surfactant, sodium oleate, reported to trigger the cubic shape, iron oxide nanoparticles with different shape and composition were observed to form. In particular, iron oxide nanoplates have been thus synthesized. The effect of the surfactant coming from precursor was taking into account by using in house iron stearates bearing either two or three stearate chains and the negative effect of water on shape was confirmed by considering these precursors after their dehydration. Nanocubes with straight faces and a FeO@Fe3-xO4 composition were obtained only with dehydrated precursors and 50% of sodium oleate in the oleic acid and sodium oleate surfactant mixtures. When iron stearates with three chains led mainly to nanocubes in presence of soduim oleate, Iron stearates with two chains led to the formation of nanoplates with 80% of sodium oleate. The original flat shape of the plates was confirmed with 3D TEM tomography. The investigation of the synthesis mechanisms confirmed the major role of deprotonated carboxylic acid and of the heating rate to drive the cubic shape of nanoparticles and showed that the nanoplate formation would depend mainly on the nucleation step and possibly on the presence of a given ratio of oleic acid and deprotonated carboxylic acid.

Characterization of Oleic-acid-coated Iron-oxide Nanoparticles Synthesized by Using a Coprecipitation Method

2014 ◽  
Vol 64 (3) ◽  
pp. 344-348
Author(s):  
Yousaf IQBAL ◽  
Ilsu RHEE ◽  
Hongsub BAE ◽  
Junghyun BYUN ◽  
Taeyoung JUNG ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Coprecipitation Method ◽  
Oxide Nanoparticles

scholarly journals Use of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) via Multiple Imaging Modalities and Modifications to Reduce Cytotoxicity: An Educational Review

2020 ◽  
Vol 1 (1) ◽  
pp. 105-135
Author(s):  
Nicholas Nelson ◽  
John Port ◽  
Mukesh Pandey
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Targeted Delivery ◽  
Superparamagnetic Iron Oxide ◽  
Superparamagnetic Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Positron Emission ◽  
Multiple Imaging ◽  
Specific Accumulation ◽  
Magnetic Resonance Imaging Mri

The aim of the present educational review on superparamagnetic iron oxide nanoparticles (SPIONs) is to inform and guide young scientists and students about the potential use and challenges associated with SPIONs. The present review discusses the basic concepts of magnetic resonance imaging (MRI), basic construct of SPIONs, cytotoxic challenges associated with SPIONs, shape and sizes of SPIONs, site-specific accumulation of SPIONs, various methodologies applied to reduce cytotoxicity including coatings with various materials, and application of SPIONs in targeted delivery of chemotherapeutics (Doxorubicin), biotherapeutics (DNA, siRNA), and positron emission tomography (PET) imaging applications.

Evaluation of cytotoxicity and genotoxicity induced by oleic acid‐coated iron oxide nanoparticles in human astrocytes

2019 ◽  
Vol 60 (9) ◽  
pp. 816-829 ◽  
Author(s):  
Natalia Fernández‐Bertólez ◽  
Carla Costa ◽  
Fátima Brandão ◽  
José Alberto Duarte ◽  
Joao Paulo Teixeira ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Human Astrocytes

Iron oxide nanoparticles modified with oleic acid: Vibrational and phase determination

2016 ◽  
Vol 99 ◽  
pp. 111-118 ◽  
Author(s):  
Paula P. Soares ◽  
Geórgia S. Barcellos ◽  
Cesar L. Petzhold ◽  
Vladimir Lavayen
Keyword(s):  
Oleic Acid ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Phase Determination

Iron oxide nanoparticles stabilized with a bilayer of oleic acid for magnetic hyperthermia and MRI applications

2016 ◽  
Vol 383 ◽  
pp. 240-247 ◽  
Author(s):  
Paula I.P. Soares ◽  
César A.T. Laia ◽  
Alexandra Carvalho ◽  
Laura C.J. Pereira ◽  
Joana T. Coutinho ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Magnetic Hyperthermia ◽  
Oxide Nanoparticles

Mechanisms of highly stabilized ex-situ oleic acid-modified iron oxide nanoparticles functionalized with 4-pentynoic acid

2018 ◽  
Vol 203 ◽  
pp. 212-222 ◽  
Author(s):  
Aainaa Aqilah Baharuddin ◽  
Bee Chin Ang ◽  
Nurul Athirah Abu Hussein ◽  
Andri Andriyana ◽  
Yew Hoong Wong
Keyword(s):  
Oleic Acid ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Ex Situ ◽  
Oxide Nanoparticles

Non-aqueous to aqueous phase transfer of oleic acid coated iron oxide nanoparticles for hyperthermia application

RSC Advances ◽  
2014 ◽  
Vol 4 (9) ◽  
pp. 4515-4522 ◽  
Author(s):  
R. M. Patil ◽  
P. B. Shete ◽  
N. D. Thorat ◽  
S. V. Otari ◽  
K. C. Barick ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Aqueous Phase ◽  
Phase Transfer ◽  
Oxide Nanoparticles

COLLOIDAL STABILITY AND MONODISPERSIBLE MAGNETIC IRON OXIDE NANOPARTICLES IN BIOTECHNOLOGY APPLICATION

2013 ◽  
Vol 12 (06) ◽  
pp. 1330002 ◽  
Author(s):  
K. SHAMILI ◽  
E. M. RAJESH ◽  
R. RAJENDRAN ◽  
S. R. MADHAN SHANKAR ◽  
M. ELANGO ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Iron Oxide Nanoparticles ◽  
Biomedical Applications ◽  
Colloidal Stability ◽  
Oxide Nanoparticles ◽  
Magnetic Iron Oxide Nanoparticles ◽  
Magnetic Fluid Hyperthermia ◽  
Magnetic Iron Oxide ◽  
Magnetic Resonance Imaging Mri ◽  
Co Precipitation

Magnetic iron oxide nanoparticles are promising material for various biological applications. In the recent decades, magnetic iron oxide nanoparticles (MNPs) have great attention in biomedical applications such as drug delivery, magnetic resonance imaging (MRI) and magnetic fluid hyperthermia (MFH). This review focuses on the colloidal stability and monodispersity properties of MNPs, which pay more attention toward biomedical applications. The simplest and the most promising method for the synthesis of MNPs is co-precipitation. The biocompatible MNPs are more interested in MRI application. This review also apportions synthesis, characterization and applications of MNP in biological and biomedical as theranostics and imaging.

Sign in / Sign up

Export Citation Format

Share Document