scholarly journals Feasibility of a Lactobacillus casei Drink in the Intensive Care Unit for Prevention of Antibiotic Associated Diarrhea and Clostridium difficile

Nutrients ◽  
2018 ◽  
Vol 10 (5) ◽  
pp. 539 ◽  
Author(s):  
Cathy Alberda ◽  
Sam Marcushamer ◽  
Tayne Hewer ◽  
Nicole Journault ◽  
Demetrios Kutsogiannis
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Clostridium Difficile ◽  
Lactobacillus Casei ◽  
Antibiotic Associated Diarrhea

Risk of Clostridium difficile-Associated Disease Among Patients Receiving Proton-Pump Inhibitors in a Quebec Medical Intensive Care Unit

2007 ◽  
Vol 28 (11) ◽  
pp. 1305-1307 ◽  
Author(s):  
Mathieu Beaulieu ◽  
David Williamson ◽  
Gilbert Pichette ◽  
Jean Lachaine
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Clostridium Difficile ◽  
Gastric Acid ◽  
Proton Pump Inhibitors ◽  
Proton Pump ◽  
Medical Intensive Care Unit ◽  
Antibiotic Use ◽  
Medical Intensive Care

Our study was conducted to determine whether use of gastric acid-suppressive agents increased the risk of Clostridium difficile-associated disease (CDAD) in a medical intensive care unit of one of the first hospitals to be threatened by the current CDAD epidemic in Quebec, Canada. Our findings suggest that efforts to determine risk factors for CDAD should focus on other areas, such as older age and antibiotic use.

An Outbreak of Clostridium difficile Necrotizing Enterocolitis

PEDIATRICS ◽  
1984 ◽  
Vol 73 (2) ◽  
pp. 266-266
Author(s):  
GRAHAM W. CHANCE ◽  
VICTOR K. M. HAN
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Clostridium Difficile ◽  
Neonatal Intensive Care Unit ◽  
Necrotizing Enterocolitis ◽  
Neonatal Intensive Care ◽  
Colonization Rate ◽  
Control Subjects

In Reply.— The observation made by Mathew et al on the lack of relationship between the isolation of Clostridium difficile and necrotizing enterocolitis (NEC) in their neonatal intensive care unit (NICU) is interesting, although the numbers are too small for relevant comment. Importantly, no mention was made on how the control subjects were selected.1 We agree that the colonization rate in NICUs may vary widely and may range up to 55% in certain units.2 In the subsequent four months following the outbreak that we reported, all infants admitted to our NICU had their stools tested weekly for C difficile.

scholarly journals Clinical features of Clostridium difficile infection in an intensive care unit: from 2009 to 2017

2018 ◽  
Vol 73 ◽  
pp. 294
Author(s):  
C. Dominguez ◽  
M. Sanchez Cunto ◽  
R. Gregori Sabelli ◽  
J. Fernandez ◽  
M. Rodriguez Llanos ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Clostridium Difficile ◽  
Clinical Features ◽  
Clostridium Difficile Infection

scholarly journals Risk Factors for diarrhea associated with Clostridium difficile in patients at a clinical hospital

2019 ◽  
Vol 91 (11) ◽  
pp. 20-25
Author(s):  
Y N Yarushina ◽  
G B Kolotova ◽  
V A Rudnov ◽  
V A Bagin
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Clostridium Difficile ◽  
Antibiotic Therapy ◽  
Case Histories ◽  
Clinical Hospital ◽  
Comorbidity Index ◽  
Autonomous Institution ◽  
Therapeutic Profile

Aim: to identify risk factors for Clostridium difficile infection in patients of a therapeutic clinic in a multidisciplinary hospital. Materials and methods. A retrospective analysis of 110 case histories of patients who were hospitalized in therapeutic departments in the Municipal Autonomous Institution “City Clinical Hospital No. 40” in Yekaterinburg (MAU City Clinical Hospital No. 40) in 2014-2015 was conducted, in which antibiotic therapy has developed diarrhea. According to the results of the study of coprofiltrate on Clostridium difficile (CD), patients were divided into 2 groups: 60 patients with a positive result and 50 patients with a negative result. Results. The proportion of patients with CD infection in the structure of patients of the therapeutic profile of the MAU GKB No.40 for 2014-2015 amounted to 0.42%. Predictors of the risk of developing diarrhea associated with CD infection in patients are: age over 65 years (OS 4.33, 95% CI 1.15-16.20, p=0.028), Charlson comorbidity index more than 2 points (OS 3.05, 95% CI 1.29-7.23, p=0.016), the presence of anemia (OR 2.32, 95% CI 1.07-5.02, p=0.048), chronic dialysis in patients with chronic renal insufficiency (CRF) (OR 8.64, 95% CI 1.05-70.81, p=0.020), patients staying in hospital for more than 5 days (OR 3.50, 95% CI 1.57-7.75, p=0.003) and hospitalization of patients in the intensive care unit (ICU) lasting more than 1 day (OS 9.80, 95% CI 1.20-79.47, p=0.011), the use of proton pump inhibitors (PPIs) (OR 2.82, 95% CI 1.12-7.11, p=0.041), antibiotic therapy more than 10 days (OS 39.62, 95% CI 10.85-144.71, p

Clostridium difficile in a neonatal intensive care unit

1997 ◽  
Vol 8 ◽  
pp. S62
Author(s):  
Amanda J. Taffinder ◽  
Tamsin A. Beal ◽  
Jill L. Shepherd ◽  
Ian F. Laurenson ◽  
Robert Brown ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Clostridium Difficile ◽  
Neonatal Intensive Care Unit ◽  
Neonatal Intensive Care

Complications of Hospital-Onset Healthcare Facility–Associated Clostridium difficile Infections Among Veterans

2016 ◽  
Vol 37 (6) ◽  
pp. 717-719 ◽  
Author(s):  
Martin E. Evans ◽  
Stephen M. Kralovic ◽  
Loretta A. Simbartl ◽  
Judith L. Whitlock ◽  
Rajiv Jain ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Clostridium Difficile ◽  
Acute Care ◽  
Healthcare Facility ◽  
Veterans Health Administration ◽  
Infect Control Hosp ◽  
Veterans Health ◽  
Health Administration ◽  
Infection Diagnosis

Complications within 30 days of a clinically confirmed hospital-onset Clostridium difficile infection diagnosis from July 1, 2012, through June 30, 2015, in 127 acute care Veterans Health Administration facilities were evaluated. Pooled rates for attributable intensive care unit admissions, colectomies, and deaths were 2.7%, 0.5%, and 0.4%, respectively.Infect Control Hosp Epidemiol 2016;37:717–719

Epidemiology of Clostridium difficile Infection Screening and Incident Cases in the Intensive Care Unit

CHEST Journal ◽  
2014 ◽  
Vol 146 (4) ◽  
pp. 219A
Author(s):  
Kelly Cawcutt ◽  
Rahul Kashyap ◽  
Gregory Wilson ◽  
Rodrigo Cartin-Ceba ◽  
Larry Baddour
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Clostridium Difficile ◽  
Clostridium Difficile Infection ◽  
Incident Cases
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