scholarly journals Effect of Branched-Chain Amino Acid Supplementation on Recovery Following Acute Eccentric Exercise

Nutrients ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1389 ◽  
Author(s):  
Trisha VanDusseldorp ◽  
Kurt Escobar ◽  
Kelly Johnson ◽  
Matthew Stratton ◽  
Terence Moriarty ◽  
...  

This study investigated the effect of branched-chain amino acid (BCAA) supplementation on recovery from eccentric exercise. Twenty males ingested either a BCAA supplement or placebo (PLCB) prior to and following eccentric exercise. Creatine kinase (CK), vertical jump (VJ), maximal voluntary isometric contraction (MVIC), jump squat (JS) and perceived soreness were assessed. No significant (p > 0.05) group by time interaction effects were observed for CK, soreness, MVIC, VJ, or JS. CK concentrations were elevated above baseline (p < 0.001) in both groups at 4, 24, 48 and 72 hr, while CK was lower (p = 0.02) in the BCAA group at 48 hr compared to PLCB. Soreness increased significantly from baseline (p < 0.01) in both groups at all time-points; however, BCAA supplemented individuals reported less soreness (p < 0.01) at the 48 and 72 hr time-points. MVIC force output returned to baseline levels (p > 0.05) at 24, 48 and 72 hr for BCAA individuals. No significant difference between groups (p > 0.05) was detected for VJ or JS. BCAA supplementation may mitigate muscle soreness following muscle-damaging exercise. However, when consumed with a diet consisting of ~1.2 g/kg/day protein, the attenuation of muscular performance decrements or corresponding plasma CK levels are likely negligible.

Andrologia ◽  
2018 ◽  
Vol 51 (2) ◽  
pp. e13183 ◽  
Author(s):  
Mehrnoosh Bahadorani ◽  
Marziyeh Tavalaee ◽  
Navid Abedpoor ◽  
Kamran Ghaedi ◽  
Mohammad N. Nazem ◽  
...  

1993 ◽  
Vol 74 (6) ◽  
pp. 2711-2717 ◽  
Author(s):  
D. A. MacLean ◽  
T. E. Graham

This study examined the effects of branched-chain amino acid (BCAA) supplementation on amino acid and ammonia (NH3) responses during prolonged exercise in humans. Seven men cycled for 60 min at 75% of maximal O2 uptake after 45 min of either placebo (dextrose, 77 mg/kg) or BCAA (leucine + isoleucine + valine, 77 mg/kg) supplementation. Plasma samples (antecubital vein) were collected at rest and during exercise and analyzed for plasma NH3 and amino acids, whole blood glucose and lactate, and serum free fatty acids and glycerol. After BCAA administration, plasma BCAA levels increased from 375 +/- 22 to 760 +/- 80 microM (P < 0.05) by the onset of exercise and remained elevated throughout the experiment. Plasma NH3 concentrations increased continually during exercise for both trials and were higher (P < 0.05) after BCAA supplementation than after placebo administration. The mean plasma NH3 increase from rest to 60 min was 79 +/- 10 and 53 +/- 4 microM for BCAA and placebo trials, respectively. Plasma alanine and glutamine concentrations were elevated (P < 0.05) during exercise for both treatments. However, only glutamine concentrations were greater (P < 0.05) for BCAA trial than for placebo trial during exercise. There were no significant differences between treatments for glucose, lactate, free fatty acids, and glycerol or any other plasma amino acid. These data suggest that increased BCAA availability before exercise, when initial muscle glycogen is normal, results in significantly greater plasma NH3 responses during exercise than does placebo administration.


2021 ◽  
Vol 53 (8S) ◽  
pp. 283-283
Author(s):  
Jesse T. Peach ◽  
Dakota Funk ◽  
Lizzi Frothingham ◽  
McMilin R. Colleen ◽  
Brian Bothner ◽  
...  

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