Potato Preload Mitigated Postprandial Glycemic Excursion in Healthy Subjects: An Acute Randomized Trial

This study investigated the preload effect of the medium and high glycemic index (GI) potato, as well as the combination of partially hydrolyzed guar gum (HG) and potato, when ingested prior to a rice meal, on the iso-carbohydrate basis. In a randomized crossover trial, 17 healthy female subjects consumed (1) rice; (2) co-ingestion of highly cooked potato (HP), and rice (HP + R); (3) co-ingestion of minimally cooked potato (MP) and rice (MP + R); (4) preload HP prior to rice meal (PHP + R); (5) preload MP prior to rice meal (PMP + R); (6) co-ingestion of partially hydrolyzed guar gum (HG), HP and rice (HG + HP + R); (7) preload HG prior to co-ingestion of HP and rice (PHG + HP + R); (8) co-preload of HG and HP prior to rice (PHG + PHP + R); and (9) preload of HP prior to co-ingestion of HG and rice (PHP + HG + R). Postprandial glycemic response (GR) tests and subjective satiety tests were conducted for each test food. Cooked potato as a preload to a rice meal could significantly cut the acute postprandial glycemic excursion by around 1.0 mmol/L, irrespective of the GI of the preload. Co-preload of partial hydrolyzed guar gum and highly cooked potato (PHG + PHP + R) resulted in improved acute GR in terms of peak glucose value and glycemic excursion compared with either HG preload or HP preload. All the meals with preload showed comparable or improved self-reported satiety. Within an equicarbohydrate exchange framework, both high-GI and medium-GI potato preload decreased the postprandial glycemic excursion in young healthy female subjects. The combination of HG and HP as double preload resulted in better GR than both single HG or HP preload did.

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Acute effect of Clitoria ternatea flower beverage on glycemic response and antioxidant capacity in healthy subjects: a randomized crossover trial

BMC Complementary and Alternative Medicine ◽

10.1186/s12906-017-2075-7 ◽

2018 ◽

Vol 18 (1) ◽

Cited By ~ 12

Author(s):

Charoonsri Chusak ◽

Thavaree Thilavech ◽

Christiani Jeyakumar Henry ◽

Sirichai Adisakwattana

Keyword(s):

Antioxidant Capacity ◽

Healthy Subjects ◽

Crossover Trial ◽

Acute Effect ◽

Glycemic Response ◽

Clitoria Ternatea ◽

Randomized Crossover Trial

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The effects of kefir in mixed meals on appetite and food intake: a randomized cross-over trial

Revista de Nutrição ◽

10.1590/1678-9865202134e190174 ◽

2021 ◽

Vol 34 ◽

Author(s):

Zeynep CAFEROGLU ◽

Gizem AYTEKIN SAHIN

Keyword(s):

Food Intake ◽

Energy Intake ◽

Glycemic Index ◽

Crossover Trial ◽

Fermented Milk ◽

Randomized Crossover Trial ◽

High Glycemic Index ◽

Dietary Strategies ◽

Healthy Females ◽

Low Glycemic Index

ABSTRACT Objective The natural probiotic kefir is fermented milk, and may have effects on satiety and voluntary energy intake. This randomized crossover trial aimed to determine whether kefir, consumed with low- or high-glycemic index meals, affects appetite and subsequent food intake. Methods Twenty four healthy females aged 21-24 years, were recruited from Erciyes University and the surrounding community. The participants were submitted to three different breakfasts: a low glycemic index accompanied by milk, a low glycemic index with kefir, and a high glycemic index with kefir, with a 1-week washout period between meals. At 0, 15, 30, 60, 90, 120, 150, and 180 minutes after the meal, appetite ratings were measured by the visual analog scale, and then ad libitum lunch was served. Results No differences in appetite scores and voluntary energy intake were detected between the test meals. Furthermore, palatability ratings were similar between test meals, except for the higher score of high glycemic index kefir for overall palatability. Conclusion This study demonstrated that adding kefir to a high glycemic index meal may prevent increases in appetite and food intake, resulting in postprandial responses similar to those of a low glycemic index meal. These findings might enable the development of novel dietary strategies based on appetite regulation to treat or prevent obesity, particularly for Western societies. This trial was registered at ClinicalTrials.gov under the process NCT03636217.

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Apple Preload Halved the Postprandial Glycaemic Response of Rice Meal in Healthy Subjects

Nutrients ◽

10.3390/nu11122912 ◽

2019 ◽

Vol 11 (12) ◽

pp. 2912 ◽

Cited By ~ 2

Author(s):

Jiacan Lu ◽

Wenqi Zhao ◽

Linlin Wang ◽

Zhihong Fan ◽

Ruixin Zhu ◽

...

Keyword(s):

Healthy Subjects ◽

Crossover Trial ◽

Sugar Solution ◽

Glycaemic Response ◽

Sugar Component ◽

Randomized Crossover Trial ◽

Healthy Female ◽

Negative Effect ◽

Sugar Profile ◽

Peak Value

This study aimed to investigate the possible glycemic effect of apple preload on acute postprandial glycemic responses (GRs) of a following rice meal, comparing with its co-ingestion counterpart and an apple sugar solution preload, based on equal carbohydrates intake. In a randomized crossover trial, 18 healthy female subjects consumed (1) rice, (2) co-ingestion of apple and rice (A+R), (3) apple preload and rice (PA+R), and (4) rice with sugar solution preload (same sugar profile as in apple) (PSS+R). Acute postprandial GR tests and subjective satiety tests were carried out for each test food. Compared with rice reference, the PA+R achieved a 50% reduction of the iAUC0-120, a 51.4% reduction of the average peak value, and a 52.6% reduction of glycemic excursion in 240 min, while the PSS+R showed 29.7% and 31.6% reduction of peak value and glycemic excursion, respectively. No significant differences were found between R and PA+R in any of the satiety characteristics. Compared with rice control, apple preload of 15 g available carbohydrates remarkably lowered the acute postprandial GR without negative effect on satiety. The sugar component may partly contribute to the glycemic suppressing effect of the apple preload.

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