Mediterranean Diet and Type 2 Diabetes Mellitus: A Perpetual Inspiration for the Scientific World. A Review

For the past 80 years, the effect of the Mediterranean diet on overall health has been a constant topic of interest among medical and scientific researchers. Parallel with the persistent global rise of cases of type 2 diabetes, many studies conducted in the past 20 years have shown the benefits of the Mediterranean lifestyle for people with, or at risk of developing, type 2 diabetes mellitus. However, despite the large body of evidence, concerns exist amongst scientists regarding the reliability of the data related to this topic. This review offers a glimpse of the onset of the Mediterranean diet and follows its significant impact on the prevention and treatment of type 2 diabetes. There is a constant rise in type 2 diabetes cases on the Balkan Peninsula and North Macedonia in particular. Having in mind that North Macedonia, as well as most of the countries on the Balkans have low to middle income, there is a need for a certain affordable dietary pattern to ameliorate the rise in diabetes incidence, as well as improve the glycemic control. We did a review based on the available literature regarding Mediterranean diet and people with or at risk of developing type 2 diabetes mellitus, its effects on glycemic control, lipid profile and metabolic outcome.

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Adherence to the Mediterranean Diet in Patients with Type 2 Diabetes Mellitus and HbA1c Level

Annals of Nutrition and Metabolism ◽

10.1159/000324718 ◽

2011 ◽

Vol 58 (1) ◽

pp. 74-78 ◽

Cited By ~ 17

Author(s):

Javier Díez-Espino ◽

Pilar Buil-Cosiales ◽

Manuel Serrano-Martínez ◽

Estefanía Toledo ◽

Jordi Salas-Salvadó ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Mediterranean Diet ◽

Hba1c Level ◽

The Mediterranean

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Psyllium fiber improves glycemic control proportional to loss of glycemic control: a meta-analysis of data in euglycemic subjects, patients at risk of type 2 diabetes mellitus, and patients being treated for type 2 diabetes mellitus

American Journal of Clinical Nutrition ◽

10.3945/ajcn.115.106989 ◽

2015 ◽

Vol 102 (6) ◽

pp. 1604-1614 ◽

Cited By ~ 45

Author(s):

Roger D Gibb ◽

Johnson W McRorie ◽

Darrell A Russell ◽

Vic Hasselblad ◽

David A D’Alessio

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

At Risk ◽

Type 2 Diabetes Mellitus ◽

Glycemic Control ◽

Meta Analysis ◽

Patients At Risk

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Genetically Guided Mediterranean Diet for the Personalized Nutritional Management of Type 2 Diabetes Mellitus

Nutrients ◽

10.3390/nu13020355 ◽

2021 ◽

Vol 13 (2) ◽

pp. 355

Author(s):

Kalliopi Gkouskou ◽

Evgenia Lazou ◽

Efstathios Skoufas ◽

Aristides G. Eliopoulos

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Glycemic Control ◽

Mediterranean Diet ◽

Healthy Lifestyle ◽

Macronutrient Composition ◽

Significant Health

The current consensus for the prevention and management of type 2 diabetes mellitus (T2DM) is that high-quality diets and adherence to a healthy lifestyle provide significant health benefits. Remarkably, however, there is little agreement on the proportions of macronutrients in the diet that should be recommended to people suffering from pre-diabetes or T2DM. We herein discuss emerging evidence that underscores the importance of gene-diet interactions in the improvement of glycemic biomarkers in T2DM. We propose that we can achieve better glycemic control in T2DM patients by coupling Mediterranean diets to genetic information as a predictor for optimal diet macronutrient composition in a personalized manner. We provide evidence to support this concept by presenting a case study of a T2DM patient who achieved rapid glycemic control when adhered to a personalized, genetically-guided Mediterranean Diet.

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Localized Subcutaneous Insulin-Derived Amyloidosis Excised after Evaluation Using Ultrasonography in a Patient with Type 2 Diabetes Mellitus

Case Reports in Endocrinology ◽

10.1155/2017/3985214 ◽

2017 ◽

Vol 2017 ◽

pp. 1-3 ◽

Cited By ~ 2

Author(s):

Seiya Hagiwara ◽

Shinji Taneda ◽

Takaya Fukumoto ◽

Kazuya Hagiwara ◽

Minoru Kikuchi ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Glycemic Control ◽

Imaging Modality ◽

Amyloid Deposition ◽

The Past ◽

Noninvasive Imaging Modality ◽

Subcutaneous Mass

A 62-year-old man with type 2 diabetes mellitus, who had been on insulin therapy for the past 20 years, was found to have subcutaneous mass formation in the abdomen during a workup of worsened glycemic control. Because of suspected amyloid deposition, he was advised to avoid injections to the mass, which led to improvement of glycemic control. However, he strongly requested mass excision and was hospitalized. After evaluation using ultrasonography and computed tomography, a total mass excision was performed, and a diagnosis of insulin-derived amyloidosis was made. Comparison of the ultrasonographic and histopathological findings demonstrated that the location of the amyloid deposition nearly corresponded to the hypoechoic region. This case highlights that ultrasonography, which is a noninvasive imaging modality, can be useful for detection of insulin-derived amyloidosis.

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