scholarly journals The Association between Carotenoids and Head and Neck Cancer Risk

Nutrients ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 88
Author(s):  
Adam Brewczyński ◽  
Beata Jabłońska ◽  
Marek Kentnowski ◽  
Sławomir Mrowiec ◽  
Krzysztof Składowski ◽  
...  

Head and neck cancer (HNC) includes oral cavity cancer (OCC), pharyngeal cancer (PC), and laryngeal cancer (LC). It is one of the most frequent cancers in the world. Smoking and alcohol consumption are the typical well-known predictors of HNC. Human papillomavirus (HPV) is an increasing etiological factor for oropharyngeal cancer (OPC). Moreover, food and nutrition play an important role in HNC etiology. According to the World Cancer Research Fund and the American Institute for Cancer Research, an intake of non-starchy vegetables and fruits could decrease HNC risk. The carotenoids included in vegetables and fruits are well-known antioxidants which have anti-mutagenic and immune regulatory functions. Numerous studies have shown the relationship between carotenoid intake and a lower HNC risk, but the role of carotenoids in HNC risk is not well defined. The goal of this review is to present the current literature regarding the relationship between various carotenoids and HNC risk.

ORL ◽  
2021 ◽  
pp. 1-3
Author(s):  
Jérôme R. Lechien ◽  
Daphné Delplace ◽  
Mohamad Khalife ◽  
Sven Saussez

Neutrophilic febrile dermatosis (NFD) is a rare paraneoplastic syndrome that may be found in patients with head and neck cancer. NFD may appear before the neoplasia and may only concern the dorsal faces of the hands. This article reports the NFD findings of a patient with pharyngeal cancer, which was developed 2 years after the occurrence of NFD. The development of NFD in patient with alcohol and tobacco consumption should lead otolaryngologists and dermatologists to suspect head and neck malignancy. In cases of normal otolaryngological examination, patients have to be followed.


2019 ◽  
Vol 188 (11) ◽  
pp. 2031-2039
Author(s):  
Patrick T Bradshaw ◽  
Jose P Zevallos ◽  
Kathy Wisniewski ◽  
Andrew F Olshan

Abstract Previous studies have suggested a “J-shaped” relationship between body mass index (BMI, calculated as weight (kg)/height (m)2) and survival among head and neck cancer (HNC) patients. However, BMI is a vague measure of body composition. To provide greater resolution, we used Bayesian sensitivity analysis, informed by external data, to model the relationship between predicted fat mass index (FMI, adipose tissue (kg)/height (m)2), lean mass index (LMI, lean tissue (kg)/height (m)2), and survival. We estimated posterior median hazard ratios and 95% credible intervals for the BMI-mortality relationship in a Bayesian framework using data from 1,180 adults in North Carolina with HNC diagnosed between 2002 and 2006. Risk factors were assessed by interview shortly after diagnosis and vital status through 2013 via the National Death Index. The relationship between BMI and all-cause mortality was convex, with a nadir at 28.6, with greater risk observed throughout the normal weight range. The sensitivity analysis indicated that this was consistent with opposing increases in risk with FMI (per unit increase, hazard ratio = 1.04 (1.00, 1.08)) and decreases with LMI (per unit increase, hazard ratio = 0.90 (0.85, 0.95)). Patterns were similar for HNC-specific mortality but associations were stronger. Measures of body composition, rather than BMI, should be considered in relation to mortality risk.


2019 ◽  
Vol 48 (4) ◽  
pp. 278-283 ◽  
Author(s):  
Shankargouda Patil ◽  
Kamran Habib Awan ◽  
Gururaj Arakeri ◽  
Abdulsalam Aljabab ◽  
Marco Ferrari ◽  
...  

2010 ◽  
Vol 1 (3) ◽  
pp. 108-113 ◽  
Author(s):  
Selvam Thavaraj ◽  
Angela Stokes ◽  
Edward W Odell

There has been a growth in publications associating human papilloma virus and head and neck squamous cell carcinoma. The virus has recently been recognised as a causative factor for some head and neck cancers that have a distinct clinical profile of site, age and prognosis. We review the epidemiological trends, mechanism of carcinogenesis, methods of detection, clinical characteristics and discuss the likely future directions of HPVassociated research in head and neck cancer.


2002 ◽  
Vol 31 (6) ◽  
pp. 329-338 ◽  
Author(s):  
T. Vuotila ◽  
L. Ylikontiola ◽  
T. Sorsa ◽  
H. Luoto ◽  
R. Hanemaaijer ◽  
...  

2008 ◽  
Vol 7 (2) ◽  
pp. 61-66
Author(s):  
T.A. Rose

AbstractIntensity-modulated radiootherapy (IMRT) is being rapidly embraced as a radiotherapy technique in many cancer centres across the world. This paper aims to highlight the reported problems associated with the use of IMRT for the treatment of head and neck cancer. Specific areas of concern that are mentioned are the identification of tumour volumes, reproducibility of treatment, issues of tumour resistance and tumour recurrence. Radiotherapy departments are advised to make haste slowly when considering the implementation of this technique.


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