scholarly journals Hematological Parameters and Iron Status in Adult Men and Women Using Altitude Adjusted and Unadjusted Hemoglobin Values for Anemia Diagnosis in Cusco, Peru (3400 MASL)

Physiologia ◽  
2022 ◽  
Vol 2 (1) ◽  
pp. 1-19
Author(s):  
Dulce E. Alarcón-Yaquetto ◽  
Ramón Figueroa-Mujica ◽  
Valeria Valverde-Bruffau ◽  
Cinthya Vásquez-Velásquez ◽  
Juan José Sánchez-Huamán ◽  
...  
Keyword(s):  
Complete Blood Count ◽  
Iron Status ◽  
Hematological Parameters ◽  
Iron Storage ◽  
Men And Women ◽  
Adult Men ◽  
The Andes ◽  
Different Populations ◽  
Personalized Approach ◽  
Current Guidelines

(1) Background: Current diagnosis of anemia in high altitude populations uses an adjustment of observed hemoglobin (Hb) values. Such an approach has been challenged by findings in different populations in Tibet, Ethiopia and the Andes as inappropriate, as it might incorrectly classify an individual with complete iron stores as anemic. We aimed to assess the suitability of this approach in adult men and women from Cusco, Peru (3400 m); (2) Methods: Complete blood count and iron status biomarkers were measured in 345 subjects (189 females and 156 males), iron status biomarkers were quantified with enzyme-linked immunoassays; (3) Results: Anemia prevalence was overestimated when the altitude-adjustment factor was applied. Hematological parameters were better correlated to iron status biomarkers in the non-adjusted anemia category. When stratified by sex, only women showed a significant association between Hb and other hematological parameters with iron storage and availability (Hepcidin and TFR-F); (4) Conclusion: The prevalence of anemia is overestimated with current guidelines. The rate of anemia using non-adjusted Hb values is more closely related to the rates of anemia or iron deficiency when used hematological parameters, markers of iron status, and measurements of hepcidin and erythropoietin. Sex differences related to iron status were observed, suggesting that men are at a higher risk of iron overload than women at high altitudes. It could be highlighted that a personalized approach is important when assessing a subject, taking in to account hematological parameters as well as origin (Southern Andean or other).

scholarly journals Hematology and Iron Status Evaluation Based on Donation Characteristics in Dr. Sardjito Hospital, Yogyakarta

2021 ◽  
Vol 27 (3) ◽  
pp. 249
Author(s):  
Fuad Anshori ◽  
Tri Ratnaningsih ◽  
Teguh Triyono
Keyword(s):  
Iron Deficiency ◽  
Blood Donors ◽  
Blood Donation ◽  
Iron Status ◽  
Statistical Significance ◽  
Hematological Parameters ◽  
Short Interval ◽  
The Body ◽  
Iron Storage ◽  
Iron Saturation

Blood donation will reduce iron storage in the body. A high frequency of donations and short interval inter-donations may increase the risk of iron deficiency. In Indonesia, detection of iron deficiency in blood donors is not a routine procedure. Therefore, the comparison of hematology and iron status based on donor characteristics is not widely known. For a month, this study was a cross-sectional study conducted at the Blood Transfusion Service Unit, Dr. Sardjito Hospital. Subjects were routine blood donors who met the criteria for donor selection; however, subjects were excluded if the CRP level was > 10 g/L and had a history of iron supplementation. Subjects were divided based on donation frequency and blood donation interval. The Kruskal-Wallis test was used to compare variables among groups with a statistical significance of p < 0.05. This study involved 145 subjects who met the criteria. Blood donations more than 20 times showed the lowest ferritin levels and iron saturation (16.9 ng/mL and 15.08%). Ferritin levels were also increased in line with the donation interval (35.5 ng/mL; 75.3 ng/mL; 92.7 ng/mL every three months). However, the hematological parameters and iron saturation did not differ significantly based on the donation interval. Hematological parameters are easy and fast procedures but have limitations in the early detection of iron deficiency. Serum ferritin has higher specificity, but its level is affected by inflammatory conditions. Ferritin levels were consistently at the lowest level in the subjects with the highest risk of iron deficiency compared to hematologic and iron saturation parameters.

Resistance Training Affects Iron Status in Older Men and Women

2001 ◽  
Vol 11 (3) ◽  
pp. 287-298 ◽  
Author(s):  
Laura E. Murray-Kolb ◽  
John L. Beard ◽  
Lyndon J. Joseph ◽  
Stephanie L. Davey ◽  
William J. Evans ◽  
...  
Keyword(s):  
Resistance Training ◽  
Binding Capacity ◽  
Iron Status ◽  
Hematological Parameters ◽  
Transferrin Saturation ◽  
Older Men ◽  
Resistance Training Program ◽  
Men And Women ◽  
Before And After ◽  
Older Men And Women

Objective:To examine the effects of resistance training on hematological and selected indices of iron status in 17 women aged 54–71 years and 18 men aged 56–69 years.Design:Tests and evaluations were done before and after all subjects participated in a resistance training program twice weekly for 12 weeks.Results:The resistance training was effective as evidenced by increases in skeletal muscle strength of 20 ± 9% and 23 ± 13% for the men and women, respectively. Hematological parameters and serum iron concentrations were within normal clinical ranges and were unchanged by resistance training for both the men and the women. Total iron binding capacity (TIBC) and transferrin saturation were also unaffected by resistance training in the women but were significantly affected in the men. The men showed a decreased TIBC (p < .0001) and an increased transferrin saturation (p = .050). Serum ferritin concentrations decreased significantly in the women (p = .041) but were unchanged in the men. Transferrin receptor concentrations were unaffected by resistance training in the women but increased significantly in the men (p = .030).Conclusions:With resistance training, iron status of older men and women changes in a sex specific way.

879: Sensitivity Mapping of Adult Men and Women Based on Sagasf Survey

2004 ◽  
Vol 171 (4S) ◽  
pp. 233-233
Author(s):  
Justine M. Schober ◽  
Heino F.L. Meyer-Bahlburg ◽  
Philip G. Ransley
Keyword(s):  
Men And Women ◽  
Adult Men

Alcohol use and aggressive behavior among adult men and women

2010 ◽  
Author(s):  
Kenneth Leonard ◽  
B. Quigley ◽  
M. Testa ◽  
R. Houston
Keyword(s):  
Alcohol Use ◽  
Aggressive Behavior ◽  
Men And Women ◽  
Adult Men

scholarly journals Dietary Fat Chain Length, Saturation, and PUFA Source Acutely Affect Diet-Induced Thermogenesis but Not Satiety in Adults in a Randomized, Crossover Trial

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2615
Author(s):  
Bret M. Rust ◽  
Susan K. Raatz ◽  
Shanon L. Casperson ◽  
Sara E. Duke ◽  
Matthew J. Picklo
Keyword(s):  
Energy Expenditure ◽  
Dietary Fatty Acids ◽  
Degree Of Saturation ◽  
Postprandial Period ◽  
Men And Women ◽  
Adult Men ◽  
Randomized Crossover Trial ◽  
Structural Differences ◽  
Diet Induced Thermogenesis ◽  
Postprandial Energy Expenditure

Structural differences in dietary fatty acids modify their rate of oxidation and effect on satiety, endpoints that may influence the development of obesity. This study tests the hypothesis that meals containing fat sources with elevated unsaturated fats will result in greater postprandial energy expenditure, fat oxidation, and satiety than meals containing fats with greater saturation. In a randomized, 5-way crossover design, healthy men and women (n = 23; age: 25.7 ± 6.6 years; BMI: 27.7 ± 3.8 kg/m2) consumed liquid meals containing 30 g of fat from heavy cream (HC), olive oil (OO), sunflower oil (SFO), flaxseed oil (FSO), and fish oil (FO). Energy expenditure and diet-induced thermogenesis (DIT) were determined by metabolic rate over a 240 min postprandial period. Serum concentrations of ghrelin, glucose, insulin, and triacylglycerol (TAG) were assessed. DIT induced by SFO was 5% lower than HC and FO (p = 0.04). Energy expenditure and substrate oxidation did not differ between fat sources. Postprandial TAG concentrations were significantly affected by fat source (p = 0.0001). Varying fat sources by the degree of saturation and PUFA type modified DIT but not satiety responses in normal to obese adult men and women.

scholarly journals Diagnostic work up of anemic patients: role of iron deficiency

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Daniela Meiser ◽  
Lale Kayikci ◽  
Matthias Orth
Keyword(s):  
Iron Deficiency ◽  
Complete Blood Count ◽  
Iron Status ◽  
Area Under The Curve ◽  
Diagnostic Value ◽  
Diagnostic Tools ◽  
Operating Characteristics ◽  
Inflammatory Conditions ◽  
Reliable Parameter ◽  
Work Up

AbstractObjectivesDiagnosing disturbances in iron metabolism can be challenging when accompanied by inflammation. New diagnostic tools such as the “Thomas-plot” (TP) (relation of soluble transferrin receptor [sTfR]/log ferritin to reticulocyte hemoglobin content [RET-He]) were established to improve classification of anemias. Aim of this retrospective study was to assess the added diagnostic value of the TP in anemia work up.MethodsPatients from December 2016 to September 2018 with a complete blood count, iron status, RET-He and sTfR were manually classified into the four quadrants of the TP on basis of conventional iron markers. Manual and algorithm-based classifications were compared using cross tabulations, Box–Whisker-Plots as well as Receiver-Operating-Characteristics (ROC) to calculate the diagnostic accuracy using Area under the Curve (AUC) analysis.ResultsA total of 3,745 patients with a conventional iron status, including 1,721 TPs, could be evaluated. In 70% of the cases the manual classification was identical to the TP, in 10% it was deviant. 20% could not clearly be classified, mostly due to inflammatory conditions. In the absence of an inflammatory condition, ferritin was a reliable parameter to define iron deficiency (ID) (AUC 0.958). In the presence of inflammation, the significance of the ferritin index (AUC 0.917) and of the RET-He (AUC 0.957) increased.ConclusionsThe TP can be useful for narrowing down the causes of anemia in complex cases. Further studies with focus on special patient groups, e.g., oncological or rheumatic patients, are desirable.

scholarly journals Body Image and Voluntary Gaze Behaviors towards Physique-Salient Images

2021 ◽  
Vol 18 (5) ◽  
pp. 2549
Author(s):  
April Karlinsky ◽  
Holly Howe ◽  
Melissa de Jonge ◽  
Alan Kingstone ◽  
Catherine M. Sabiston ◽  
...  
Keyword(s):  
Body Image ◽  
Media Consumption ◽  
Negative Consequences ◽  
Body Appreciation ◽  
Men And Women ◽  
Physical Strength ◽  
Adult Men ◽  
Self Perceptions ◽  
Before And After ◽  
Image Variables

The purpose of this study was to explore body image correlates of voluntary consumption of physique-salient media. A secondary aim was to assess changes in affect following media consumption. Young adult men (n = 47; mean age = 20.2 years) and women (n = 87; mean age = 19.5 years) were discretely exposed to images of same-sex models with idealized- and average-physiques while completing an irrelevant computer task. Voluntary gaze at the images was covertly recorded via hidden cameras. Participants also completed measures of affect before and after the computer task. Measures of body-related envy, body appreciation, and self-perceptions of attractiveness, thinness, and physical strength were completed. Men and women did not differ in how often nor for how long they looked at the images overall, but body image variables were differentially associated with their voluntary gaze behaviors. For men, higher body-related envy and lower body appreciation were correlated with more looks at the average-physique model. Although women reported higher body-related envy than men, envy and body appreciation were not significant correlates of gaze behaviors for women. Both men and women experienced a general affective decrease over time, but only for men was the change in negative affect associated with their time spent looking at the ideal-physique image. Overall, these findings suggest that body-related envy and body appreciation influence how men choose to consume physique-salient media, and that media consumption may have negative consequences for post-exposure affect. Body image factors appear to be more strongly associated with behavior in men, perhaps because men are generally less often exposed to physique-salient media and, in particular, to average-physique images.

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