scholarly journals The Selectivity of Molecularly Imprinted Polymers

Polymers ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 1781
Author(s):  
Gergely Becskereki ◽  
George Horvai ◽  
Blanka Tóth
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Solid Phase ◽  
Practical Method ◽  
Batch Adsorption ◽  
Phase Extraction ◽  
Target Compound ◽  
Binding Assays ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Imprinted Polymers

The general claim about novel molecularly imprinted polymers is that they are selective for their template or for another target compound. This claim is usually proved by some kind of experiment, in which a performance parameter of the imprinted polymer is shown to be better towards its template than towards interferents. A closer look at such experiments shows, however, that different experiments may differ substantially in what they tell about the same imprinted polymer’s selectivity. Following a short general discussion of selectivity concepts, the selectivity of imprinted polymers is analyzed in batch adsorption, binding assays, chromatography, solid phase extraction, sensors, membranes, and catalysts. A number of examples show the problems arising with each type of application. Suggestions for practical method design are provided.

Simple and selective detection of quercetin in extracts of plants and food samples by dispersive-micro-solid phase extraction based on core–shell magnetic molecularly imprinted polymers

2018 ◽  
Vol 42 (19) ◽  
pp. 16144-16153 ◽  
Author(s):  
Arash Asfaram ◽  
Maryam Arabi ◽  
Abbas Ostovan ◽  
Hossein Sadeghi ◽  
Mehrorang Ghaedi
Keyword(s):  
Molecularly Imprinted Polymers ◽  
Solid Phase ◽  
Food Samples ◽  
Selective Detection ◽  
Phase Extraction ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Magnetic Molecularly Imprinted Polymer ◽  
Magnetic Molecularly Imprinted Polymers

In the present study, a D-μ-SPE clean-up method was established for the analysis of quercetin in extracts of plants and food samples using a magnetic molecularly imprinted polymer as the sorbent by HPLC-UV detection.

scholarly journals Determination of sialic acid in serum samples by dispersive solid-phase extraction based on boronate-affinity magnetic hollow molecularly imprinted polymer sorbent

RSC Advances ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 5394-5401 ◽  
Author(s):  
Wei Huang ◽  
Xingyu Hou ◽  
Yukui Tong ◽  
Miaomiao Tian
Keyword(s):  
Sialic Acid ◽  
Molecularly Imprinted Polymers ◽  
Solid Phase ◽  
Phase Extraction ◽  
Dispersive Solid Phase Extraction ◽  
Imprinted Polymer ◽  
Serum Samples ◽  
Molecularly Imprinted ◽  
Imprinted Polymers

Boronate-affinity magnetic hollow molecularly imprinted polymers were prepared with sialic acid (SA) as a template to selectively extract SA from serum samples coupled with HPLC-UV.

Application of hollow porous molecularly imprinted polymers using K2Ti4O9 coupled with SPE-HPLC for the determination of celecoxib in human urine samples: optimization by central composite design (CCD)

2017 ◽  
Vol 9 (21) ◽  
pp. 3200-3212 ◽  
Author(s):  
S. Ansari
Keyword(s):  
Molecularly Imprinted Polymers ◽  
High Performance ◽  
Solid Phase ◽  
Trace Determination ◽  
Phase Extraction ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Central Composite

Trace determination of celecoxib by hollow porous molecularly imprinted polymer and solid-phase extraction (HPMIP-SPE) coupled with high-performance liquid chromatography with UV detection (HPLC/UV).

Preparation of nicotine surface molecularly imprinted polymers for selective solid-phase extraction of nicotine from zero-level refill liquids of electronic cigarettes

2018 ◽  
Vol 10 (29) ◽  
pp. 3637-3644 ◽  
Author(s):  
Juanjuan Xie ◽  
Bo Zhou ◽  
Tiandong Zhang ◽  
Xiaoying Zeng ◽  
Mochou Yang ◽  
...  
Keyword(s):  
Solid Phase Extraction ◽  
Molecularly Imprinted Polymers ◽  
Solid Phase ◽  
Electronic Cigarettes ◽  
Phase Extraction ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Zero Level

Preparation of surface molecularly imprinted polymer for the determination of nicotine in the zero-level refill liquids of electronic cigarettes.

scholarly journals Imprinted polymers in analytical chemistry

2021 ◽  
Vol 9 (3) ◽  
Author(s):  
Jozef Lehotay ◽  
Miroslava Lachová ◽  
Ján Mocák
Keyword(s):  
Analytical Chemistry ◽  
Solid Phase Extraction ◽  
Molecularly Imprinted Polymers ◽  
Solid Phase ◽  
Phase Extraction ◽  
Imprinted Polymer ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Polymer Properties ◽  
Polymerization Mixture

Molecularly imprinted polymers were prepared and tested in different way. 1-methyl-2-piperidinoethylester of 4-decyloxyphenylcarbamic acid was used as template for imprints formation. Acrylamide, 4-vinylpyridine and methacrylic acid as monomers and methanol and acetonitrile as a porogene were used. Non-imprinted polymers (NIP) were prepared for each imprinted polymer by the same procedure. Polymers were employed as sorbents for solid-phase extraction (SPE). In this work the influence of polymerization mixture composition on polymer properties, such as capacity and selectivity, was investigated. The influence of alkoxy-chain length and position on benzene ring on the selectivity of polymers was also investigated.

Highly selective enrichment and direct determination of imazethapyr residues from milk using magnetic solid-phase extraction based on restricted-access molecularly imprinted polymers

2021 ◽  
Author(s):  
Shicong Jia ◽  
yanqiang zhou ◽  
Jianmin Li ◽  
Bolin Gong ◽  
Shujuan Ma ◽  
...  
Keyword(s):  
Solid Phase Extraction ◽  
Molecularly Imprinted Polymers ◽  
Solid Phase ◽  
Direct Determination ◽  
Magnetic Solid Phase Extraction ◽  
Phase Extraction ◽  
Molecularly Imprinted ◽  
Restricted Access ◽  
Imprinted Polymers ◽  
Magnetic Solid

The restricted access media magnetic molecularly imprinted polymers (RAM-MMIPs) were prepared as magnetic solid phase extraction (M-SPE) material by reversible addition fragmentation chain transfer (RAFT) technique. The resulting RAM-MMIPs had...

The Application of Molecularly Imprinted Polymers to Solid-Phase Extraction

2014 ◽  
Vol 893 ◽  
pp. 283-286
Author(s):  
Hong Ying Pei ◽  
Gui Jun Shen ◽  
Yu Du
Keyword(s):  
Solid Phase Extraction ◽  
Molecularly Imprinted Polymers ◽  
Biological Samples ◽  
Solid Phase ◽  
Phase Extraction ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Structural Analogues ◽  
Environmental And Biological Samples

A benefit of imprinted polymers is the possibility to prepare sorbents with selectivity pre-determined for a particular substance, or group of structural analogues. The application most close to a wider acceptance is probably that of solid phase extraction for clean-up of environmental and biological samples. The technique of molecularly imprinted polymers to solid phase extraction (MISPE) is performance and high selectively, compared with traditional sorbents. In this paper, the preparation and application of MIPs would be reviewed.

scholarly journals Development of Surface Molecularly Imprinted Polymers as Dispersive Solid Phase Extraction Coupled with HPLC Method for the Removal and Detection of Griseofulvin in Surface Water

2019 ◽  
Vol 17 (1) ◽  
pp. 134 ◽  
Author(s):  
Kamran Bashir ◽  
Zhimin Luo ◽  
Guoning Chen ◽  
Hua Shu ◽  
Xia Cui ◽  
...  
Keyword(s):  
Surface Water ◽  
Solid Phase Extraction ◽  
Molecularly Imprinted Polymers ◽  
Water Samples ◽  
Solid Phase ◽  
Phase Extraction ◽  
Dispersive Solid Phase Extraction ◽  
Molecularly Imprinted ◽  
Imprinted Polymers ◽  
Surface Water Samples

Griseofulvin (GSF) is clinically employed to treat fungal infections in humans and animals. GSF was detected in surface waters as a pharmaceutical pollutant. GSF detection as an anthropogenic pollutant is considered as a possible source of drug resistance and risk factor in ecosystem. To address this concern, a new extraction and enrichment method was developed. GSF-surface molecularly imprinted polymers (GSF-SMIPs) were prepared and applied as solid phase extraction (SPE) sorbent. A dispersive solid phase extraction (DSPE) method was designed and combined with HPLC for the analysis of GSF in surface water samples. The performance of GSF-SMIPs was assessed for its potential to remove GSF from water samples. The factors affecting the removal efficiency such as sample pH and ionic strength were investigated and optimized. The DSPE conditions such as the amount of GSF-SMIPs, the extraction time, the type and volume of desorption solvents were also optimized. The established method is linear over the range of 0.1–100 µg/mL. The limits of detection and quantification were 0.01 and 0.03 µg/mL respectively. Good recoveries (91.6–98.8%) were achieved after DSPE. The intra-day and inter-day relative standard deviations were 0.8 and 4.3% respectively. The SMIPs demonstrated good removal efficiency (91.6%) as compared to powder activated carbon (67.7%). Moreover, the SMIPs can be reused 10 times for water samples. This is an additional advantage over single-use activated carbon and other commercial sorbents. This study provides a specific and sensitive method for the selective extraction and detection of GSF in surface water samples.

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