scholarly journals A Case Report of Primordial Odontogenic Tumor That Required Distinction from a Dentigerous Cyst

Reports ◽  
2021 ◽  
Vol 4 (1) ◽  
pp. 4
Author(s):  
Sawako Ono ◽  
Hotaka Kawai ◽  
Shintaro Sukegawa ◽  
Kiyofumi Takabatake ◽  
Keisuke Nakano ◽  
...  
Keyword(s):  
Root Resorption ◽  
Dentigerous Cyst ◽  
Fibrous Tissue ◽  
Clinical Findings ◽  
Odontogenic Tumor ◽  
Columnar Epithelium ◽  
Solid Mass ◽  
Histological Differentiation ◽  
Second Molar ◽  
Primordial Odontogenic Tumor

Primordial odontogenic tumor (POT) is a rare odontogenic tumor characterized by a variably cellular loose fibrous tissue with areas similar to the dental papilla and covered by cuboidal to columnar epithelium. We herein report a case of POT in a 14-year-old boy. Computed tomography (CT) exhibited a round cavity with a defined cortical border circumscribing the tooth of the second molar. However, the gross finding was a solid mass, not a cyst. Histologically, the tumor consisted of dental papillalike myxoid connective tissue covered by columnar epithelium. Therefore, although the clinical diagnosis was dentigerous cyst (DC), we diagnosed POT based on histologic findings. Clinical findings of POT resemble DC, but the clinical behavior of POT is different to DC, such as cortical expansion and root resorption of teeth. Therefore, histological differentiation of POT from DC is critical for accurate diagnosis.

scholarly journals The Challenging Diagnosis of Primordial Odontogenic Tumor

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Lucas Novaes Teixeira ◽  
Cristiane Furuse ◽  
Fabrício Passador Santos ◽  
Andresa Borges Soares ◽  
Eder Magno Ferreira de Oliveira ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Young Patients ◽  
Odontogenic Tumor ◽  
Columnar Epithelium ◽  
Anatomic Site ◽  
Loose Connective Tissue ◽  
Similar Morphology ◽  
Dental Papilla ◽  
Unerupted Tooth ◽  
Primordial Odontogenic Tumor

Primordial odontogenic tumor (POT) is a benign mixed odontogenic tumor comprised of a loose connective tissue with a similar morphology with dental papilla and exhibiting in its periphery the presence of a columnar epithelium. POT occurs in young patients and typically is associated with an unerupted tooth, with the mandible being the main anatomic site of occurrence. The present manuscript is aimed at describing a new case of POT and reviewing the main biologic findings related to this odontogenic tumor.

scholarly journals Síndrome da deleção 2q37.3 – A primeira descrição de achados orais, relato de caso

2021 ◽  
Vol 62 (1) ◽  
pp. 162-172
Author(s):  
Carolina Maschietto Pucinelli ◽  
Raquel Assed Bezerra Segato ◽  
Paulo Nelson-Filho ◽  
Léa Assed Bezerra Da Silva ◽  
Vivian Vicentin Massoni ◽  
...  
Keyword(s):  
Behavior Management ◽  
Dental Treatment ◽  
Dentigerous Cyst ◽  
Clinical Findings ◽  
Open Bite ◽  
Deletion Syndrome ◽  
Chromosome 2 ◽  
Congenital Diseases ◽  
Second Molar ◽  
Increased Risk

Introduction: The 2q37.3 deletion syndrome is a disorder caused by the microdeletion of a subband on chromosome 2, whose epidemiology is approximately 150 cases worldwide, and the prevalence of 1: 10000. Its characteristics are developmental delay, facial dysmorphia, musculoskeletal abnormalities, and increased risk of congenital diseases. The purpose is to present, for the first time in the literature, the oral and dental clinical findings associated with the syndrome. Case report: The main physical characteristics of the syndrome were identified during the physical examination: thin upper lip, prominent columella, and epicanthic folds. In the intraoral examination, dental characteristics were reported, which may be associated with the syndrome: accumulation of dental calculus, hypomineralization and hypoplasia, crossbite, open bite, agenesis, taurodontism, and dentigerous cyst. The dental treatment consisted of the application of behavior management techniques, hygiene and diet instruction, prophylaxis, supragingival scraping, topical fluoride application, and extraction of the lower second molar. This is the first report of oral characteristics of the 2q37.3 deletion syndrome, giving importance to the characteristics observed in this patient. Such findings will be useful in the characterization of the syndrome, which is extremely rare, and may contribute to the clinical diagnosis of these patients, in addition to subsidizing the dental treatment of other individuals. Conclusion: We present oral clinical findings such as hypomineralization and hypoplasia, crossed and an open bite, agenesis, taurodontism, and dentigerous cyst present in the patient with the syndrome and we suggest that the involved gene or its deletion may be responsible for such findings.

Evaluation of Biological Behavior of Keratocyst Odontogenic Tumor Based on Clinical Findings, Histology, and Radiographic Findings Through Epidemiologic Survey at São Leopoldo de Mandic C.P.O.

2014 ◽  
Vol 117 (2) ◽  
pp. e206
Author(s):  
LUCAS CORREA HOMSE ◽  
RAFAEL CLAUDINO LINS ◽  
ANAMARIA DE LIMA LARANJEIRA ◽  
MILENA BORTOLOTTO FELIPPE SILVA ◽  
SILVIA CRISTINA MAZETI TORRES ◽  
...  
Keyword(s):  
Clinical Findings ◽  
Odontogenic Tumor ◽  
Biological Behavior ◽  
Radiographic Findings ◽  
Epidemiologic Survey

Evaluation of the Connective Tissue Wall in Sporadic Cases of Keratocystic Odontogenic Tumor (KCOT) Using MMP-9 and Confocal Microscopy: A Retrospective Study

2021 ◽  
Vol 12 (1) ◽  
pp. 134-143
Author(s):  
Merlin Jayaraj ◽  
Pratibha Ramani ◽  
Herald J. Sherlin
Keyword(s):  
Confocal Microscopy ◽  
Connective Tissue ◽  
Dentigerous Cyst ◽  
Odontogenic Tumor ◽  
Biological Behavior ◽  
Keratocystic Odontogenic Tumor ◽  
Extracellular Matrix Components ◽  
Sporadic Cases ◽  
Odontogenic Lesion ◽  
Inherent Nature

Background: Keratocystic odontogenic tumor (KCOT) is an odontogenic lesion which manifests distinct biological behavior. Predominant studies in KCOT attribute this behavior to high epithelial proliferative capacity. Besides, a few studies facet loosely arranged collagen can contribute to the behavior of KCOT. Matrix metalloproteinases (MMP) are enzymes that degrade extracellular matrix components under both physiologic and pathologic conditions. The loosely arranged collagen in connective tissue wall of KCOT could be related to the degree of MMP-9 expression. Aim: To evaluate the arrangement of collagen fibers along with immunoexpression of MMP-9 and to relate to its neoplastic biologic behavior in sporadic cases of KCOT. Materials and Methods: KCOT ( n = 23) and dentigerous cyst (DC) ( n = 15) samples were processed for the following techniques: Masson’s trichrome stain for light microscopy, PMA-PSR stain for confocal microscopy, and MMP-9 for immunohistochemistry. Results: In Masson’s trichrome analysis, correlation of collagen fiber arrangement in the deeper regions with color intensity for KCOT was found to be statistically significant ( P = .033). In confocal microscopy, there was no difference between intensities in KCOT ( P = .990) and DC ( P = .233), respectively. The immunoexpression of MMP-9 in the connective tissue wall of DC (73.3%) was relatively higher than that of KCOT (60.8%). However, on comparison between KCOT and DC in the presence of inflammation, the immunoexpression of MMP-9 was higher in DC (100%) than KCOT (69.9%) and was statistically significant ( P = .028). Conclusion: It was concluded that the loose connective tissue wall in KCOT is because of the inherent nature of the lesion that could facilitate its biologic behavior. If inflammation is present, this could further aggravate the tumorigenic behavior.

Squamous Odontogenic Tumor-Like Proliferation in a Dentigerous Cyst: a Case Report

2018 ◽  
Vol 126 (3) ◽  
pp. e42
Author(s):  
Camila De Oliveira Barbeiro ◽  
Heitor Albergoni Da Silveira ◽  
Darcy Fernandes ◽  
Raphael Carlos Comelli Lia ◽  
Jorge Esquiche Leon ◽  
...  
Keyword(s):  
Case Report ◽  
Dentigerous Cyst ◽  
Odontogenic Tumor

scholarly journals A rare case of massif Adenomatoid Odontogenic Tumor in the anterior region of mandible: Mimicking as dentigerous cyst

2015 ◽  
Vol 27 (3) ◽  
Author(s):  
Aris Munandar ◽  
Endang Syamsudin ◽  
Melita Sylvyana ◽  
Kiki Akhmad Rizki
Keyword(s):  
Dentigerous Cyst ◽  
Final Diagnosis ◽  
Odontogenic Tumor ◽  
Radiographic Examination ◽  
Adenomatoid Odontogenic Tumor ◽  
Impacted Tooth ◽  
Unusual Site ◽  
Radiographic Features ◽  
Odontogenic Epithelium ◽  
Anterior Mandible

Background. Adenomatoid Odontogenic Tumor (AOT) is a rare tumor of epithelial origin. AOT appears in three clinico-topographic variants: follicular, extrafollicular and peripheral. The AOT was predominantly found in the upper jaw, and rarely found in mandible, especially at anterior mandible. AOT is a tumor of odontogenic epithelium having duct like structures, which may be partly cystic, and in some cases the solid lesion may be present only as masses in the wall of a large cyst. The surgical management of this lesion would be enucleation along with removal of associated impacted tooth. The prognosis for both of them is good and recurrences are very rare after complete removal of the lesion. Purpose. It is important to define final diagnose for AOT due to mimicking with DC in clinically and radiographically finding. Biopsy is still obviously necessary to the final diagnosis. Case. 15-year-old female patients reported with chief complain of swelling in anterior mandible. The swelling beginning 4 years ago, gradually progressed, with no history pain, discharge and patient is complaint about loss of sensation around anterior mandible. Aspiration revealed straw colored fluid thinking in the way of DC. The provisional diagnosis of DC was given due to clinical presentation and radiographic imaging. But the biopsy examination showed AOT due to duct-like epithelial cells was being found. Discussion. The case report illustrates characteristic clinical and radiographic features of follicular variant of AOT mimicking a DC at unusual site that is anterior mandible. AOT is thought to arise from odontogenic epithelium and associated with the impacted tooth. Rightfully AOT is a perfect imitator of DC radiographically as well as histopathologically. It usually clinically misdiagnosed as DC as both have a unilocular, well-defined radiolucency surrounding the crown of an impacted tooth. The mass was enucleated, involved teeth were extracted, and titanium plates are used to avoid pathologist fracture. The patient had uneventful postoperative recovery. Follow up of a year has not shown any evidence of recurrence. Conclusion. Follicular type of OAT could confuse us with DC if the support examination just only clinicaly finding and radiographic examination. This case could not be definitively diagnosed on clinical and radiographic features alone. Biopsy was obviously necessary to the final diagnosis.

scholarly journals Karsinoma Odontogenik Sel Jernih

2015 ◽  
Vol 1 (1) ◽  
pp. 31-40
Author(s):  
Rino Rusdiono ◽  
Arif Faisal
Keyword(s):  
Ct Scan ◽  
Clear Cell ◽  
Histopathological Examination ◽  
Dentigerous Cyst ◽  
Odontogenic Tumor ◽  
Tissue Mass ◽  
Maxillary Bone ◽  
Imaging Examination ◽  
Odontogenic Carcinoma ◽  
Molar Region

Odontogenic tumor is a lesion originated from epithelium, ectomesenchymal, or mesenchymal component which still retain part of dental-forming element.A female 20 years old had complaint a mass in the oral cavity and obtructed nasal. Physical examination showed a mass on molar region of the left axillary bone. Diagnostic imaging by using OPG was suspected ameloblastoma, while CT scan concluded as a dentigerous cyst in left maxillary bone. Both of the lesions were cystic  abnormalities, that sometimes very difcult to di?erentiate due to their similarity. Pathological fndings was clear cell odontogenic tumor or clear cell odontogenic carcinoma of tissue mass after resection had been conducted. This case report is proposed because there is a discordance from imaging examination in both OPG and CT Scan with the fnal histopathological examination. CCOC di?erential diagnosis will be outlined here so we can understand the feature of CCOC better in imaging examination to prevent misdiagnosis which can infere further treatment.

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