scholarly journals The Challenging Diagnosis of Primordial Odontogenic Tumor

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Lucas Novaes Teixeira ◽  
Cristiane Furuse ◽  
Fabrício Passador Santos ◽  
Andresa Borges Soares ◽  
Eder Magno Ferreira de Oliveira ◽  
...  
Keyword(s):  
Connective Tissue ◽  
Young Patients ◽  
Odontogenic Tumor ◽  
Columnar Epithelium ◽  
Anatomic Site ◽  
Loose Connective Tissue ◽  
Similar Morphology ◽  
Dental Papilla ◽  
Unerupted Tooth ◽  
Primordial Odontogenic Tumor

Primordial odontogenic tumor (POT) is a benign mixed odontogenic tumor comprised of a loose connective tissue with a similar morphology with dental papilla and exhibiting in its periphery the presence of a columnar epithelium. POT occurs in young patients and typically is associated with an unerupted tooth, with the mandible being the main anatomic site of occurrence. The present manuscript is aimed at describing a new case of POT and reviewing the main biologic findings related to this odontogenic tumor.

scholarly journals A Case Report of Primordial Odontogenic Tumor That Required Distinction from a Dentigerous Cyst

Reports ◽  
2021 ◽  
Vol 4 (1) ◽  
pp. 4
Author(s):  
Sawako Ono ◽  
Hotaka Kawai ◽  
Shintaro Sukegawa ◽  
Kiyofumi Takabatake ◽  
Keisuke Nakano ◽  
...  
Keyword(s):  
Root Resorption ◽  
Dentigerous Cyst ◽  
Fibrous Tissue ◽  
Clinical Findings ◽  
Odontogenic Tumor ◽  
Columnar Epithelium ◽  
Solid Mass ◽  
Histological Differentiation ◽  
Second Molar ◽  
Primordial Odontogenic Tumor

Primordial odontogenic tumor (POT) is a rare odontogenic tumor characterized by a variably cellular loose fibrous tissue with areas similar to the dental papilla and covered by cuboidal to columnar epithelium. We herein report a case of POT in a 14-year-old boy. Computed tomography (CT) exhibited a round cavity with a defined cortical border circumscribing the tooth of the second molar. However, the gross finding was a solid mass, not a cyst. Histologically, the tumor consisted of dental papillalike myxoid connective tissue covered by columnar epithelium. Therefore, although the clinical diagnosis was dentigerous cyst (DC), we diagnosed POT based on histologic findings. Clinical findings of POT resemble DC, but the clinical behavior of POT is different to DC, such as cortical expansion and root resorption of teeth. Therefore, histological differentiation of POT from DC is critical for accurate diagnosis.

scholarly journals Morphology of the male agouti accessory genital glands (Dasyprocta prymnolopha Wagler, 1831)

2010 ◽  
Vol 30 (9) ◽  
pp. 793-797 ◽  
Author(s):  
Danilo J. Ayres de Menezes ◽  
Antonio C. Assis Neto ◽  
Moacir F. Oliveira ◽  
E.C. Farias
Keyword(s):  
Connective Tissue ◽  
Columnar Epithelium ◽  
Alveolar Type ◽  
Morphological Aspect ◽  
Macroscopic Description ◽  
Similar Morphology ◽  
In Captivity ◽  
Histological Characteristics ◽  
Hematoxylin Eosin

The morphology of the accessory genital glands of the male agouti was studied in twenty-three animals that were raised in captivity. Twenty animals had their genital glands dissected in situ for macroscopic description. The samples of each gland were recovered, embedded in paraffin, sliced and stained by Hematoxylin-Eosin technique. It was founded four pairs of glands: the vesicular glands, the coagulating glands, the prostate and the bulbourethral glands. Histological characteristics of the vesicular, coagulating and prostate glands showed similar morphology, within the pseudostratified columnar epithelium. The tubulo-alveolar type of the bulbourethral glands showed a lack of connective tissue among the tubules, a small amount of red stained presented it the cytoplasm, and the presence of vacuoles in the tissue. This study concluded that the agouti showed to have similar morphological aspect described in the others species of rodents.

scholarly journals STUDY ON POSTNATAL GROWTH AND DEVELOPMENT OF CROP AND PROVENTRICULUS OF DIGESTIVE TRACT OF BROILER

2018 ◽  
Vol 16 (1) ◽  
pp. 7-11
Author(s):  
K. Akter ◽  
M. T. Mussa ◽  
M. A. Sayeed ◽  
M. A. Hai ◽  
M. M. Uddin
Keyword(s):  
Smooth Muscle ◽  
Connective Tissue ◽  
Digestive Tract ◽  
Growth And Development ◽  
Histological Study ◽  
Age Groups ◽  
Postnatal Growth ◽  
Columnar Epithelium ◽  
Loose Connective Tissue ◽  
Tunica Muscularis

The experiment was carried out to investigate postnatal growth and development of crop and proventriculus of digestive tract of broiler. Total 45 (“Cobb-500”) chickens of three age groups like day 1(D1), day14 (D14), day 28 (D28) were used each group containing fifteen chickens. All birds were slaughtered after respective days then crop and proventriculus were collected. Total length, diameter and weight were determined by “slide calipers” and electronic balance. Then the samples were processed and stained with H and E stain for histological study. The length (cm), diameter (cm) and weight (gm) of crop and proventriculus were increased gradually with the age where highest at 28 and lowest at day 1. Number of mucosal folds of crop was highest at 1 and lowest at day 28. The keratinized stratified squamous epithelium of crop was thickest at day 28. Submucosa contains thin loose connective tissue. Tunica muscularis contains thick inner circular and thinner outer longitudinal smooth muscle and externally covered by adventitia. The mucosa of the proventriculus has macroscopic papillae with numerous folds and lined by simple columnar epithelium. Submucosal glands are lined by simple cuboidal to low columnar epithelium. Lamina propria contains loose connective tissue and muscularis contains scattered bundles of smooth muscle. Tunica muscularis consists of smooth muscle and externally covered by serosa.

scholarly journals Case Report: A Primordial odontogenic tumor

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 562 ◽  
Author(s):  
Hatem Amer ◽  
Layla Hafed ◽  
Sally Ibrahim
Keyword(s):  
Case Report ◽  
Ct Scan ◽  
Clinical Finding ◽  
Odontogenic Tumor ◽  
Odontogenic Tumors ◽  
Enamel Organ ◽  
Aggressive Treatment ◽  
Dental Papilla ◽  
Multilocular Radiolucency ◽  
Primordial Odontogenic Tumor

Introduction: Primordial odontogenic tumors are a rare recently described mixed odontogenic tumor composed histopathologically of dental papilla like tissue and enamel organ like tissue. Only nine cases have been documented worldwide and we are reporting the tenth case which is from Egypt. Clinical finding: A 2-year-old Egyptian boy that presented with an asymptomatic swelling of the mandible which appeared with multilocular radiolucency associated with an impacted developing tooth on a computerized tomography (CT) scan. Diagnoses, interventions, and outcomes: The lesion was excised and diagnosed as a primordial odontogenic tumor. The patient was followed up for two years with no recurrence. Conclusion: Differentiation of primordial odontogenic tumors from other odontogenic tumors, which resemble it histopathologically is crucial to avoid unnecessary aggressive treatment.

scholarly journals I. A contribution to the anatomy of the ductless glands and lymphatic system of the angler fish ( Lophius piscatorius )

1927 ◽  
Vol 215 (421-430) ◽  
pp. 1-56 ◽  
Keyword(s):  
Connective Tissue ◽  
Lymphatic System ◽  
Loose Connective Tissue ◽  
Mode Of Life ◽  
Better Than ◽  
Considerable Size

The Angler ( Lophius piscatorius ) is a fish much modified for a bottom habit, and apart from many peculiarities of form and structure associated with this particular mode of life, is remarkable for the looseness of its skin and the abundance of soft connective tissue that separates it from the underlying fascia and muscles. Within this layer of loose connective tissue lie many of the larger trunks of the lymphatic system, mostly of very considerable size and easy to inject. The fish thus furnishes material better than most for the study of this system.

Histopathology of the A1 Pulley in Adult Trigger Fingers

2007 ◽  
Vol 32 (5) ◽  
pp. 556-559 ◽  
Author(s):  
M. C. SBERNARDORI ◽  
P. BANDIERA
Keyword(s):  
Connective Tissue ◽  
Middle Layer ◽  
Laminar Structure ◽  
Loose Connective Tissue ◽  
Control Series ◽  
Outermost Layer ◽  
Additional Layer ◽  
Transmission Electron ◽  
Electron Microscopes ◽  
A1 Pulley

The histopathology of the central parts of 40 A1 pulleys from adult patients with primary trigger fingers was studied using light and transmission electron microscopes and the findings were compared with those in a control series of 10 normal A1 pulleys. The evaluation of the normal A1 pulley revealed a bi-laminar structure. The deepest layer was composed of dense normal connective tissue. The outermost layer was formed by loose connective tissue. In trigger digits, it was possible to identify a tri-laminar structure. The deepest layer was composed of irregular connective tissue, formed by small collagen fibres and abundant extracellular matrix. A considerable amount of chondroid-metaplasia was present in this layer. The middle layer contained dense, normal connective tissue with some fibrocytes. The outermost layer was formed of loose connective tissue. In conclusion, there was an additional layer in the A1 pulley in pathological cases which was not present in normal pulleys.

Evaluation of the Connective Tissue Wall in Sporadic Cases of Keratocystic Odontogenic Tumor (KCOT) Using MMP-9 and Confocal Microscopy: A Retrospective Study

2021 ◽  
Vol 12 (1) ◽  
pp. 134-143
Author(s):  
Merlin Jayaraj ◽  
Pratibha Ramani ◽  
Herald J. Sherlin
Keyword(s):  
Confocal Microscopy ◽  
Connective Tissue ◽  
Dentigerous Cyst ◽  
Odontogenic Tumor ◽  
Biological Behavior ◽  
Keratocystic Odontogenic Tumor ◽  
Extracellular Matrix Components ◽  
Sporadic Cases ◽  
Odontogenic Lesion ◽  
Inherent Nature

Background: Keratocystic odontogenic tumor (KCOT) is an odontogenic lesion which manifests distinct biological behavior. Predominant studies in KCOT attribute this behavior to high epithelial proliferative capacity. Besides, a few studies facet loosely arranged collagen can contribute to the behavior of KCOT. Matrix metalloproteinases (MMP) are enzymes that degrade extracellular matrix components under both physiologic and pathologic conditions. The loosely arranged collagen in connective tissue wall of KCOT could be related to the degree of MMP-9 expression. Aim: To evaluate the arrangement of collagen fibers along with immunoexpression of MMP-9 and to relate to its neoplastic biologic behavior in sporadic cases of KCOT. Materials and Methods: KCOT ( n = 23) and dentigerous cyst (DC) ( n = 15) samples were processed for the following techniques: Masson’s trichrome stain for light microscopy, PMA-PSR stain for confocal microscopy, and MMP-9 for immunohistochemistry. Results: In Masson’s trichrome analysis, correlation of collagen fiber arrangement in the deeper regions with color intensity for KCOT was found to be statistically significant ( P = .033). In confocal microscopy, there was no difference between intensities in KCOT ( P = .990) and DC ( P = .233), respectively. The immunoexpression of MMP-9 in the connective tissue wall of DC (73.3%) was relatively higher than that of KCOT (60.8%). However, on comparison between KCOT and DC in the presence of inflammation, the immunoexpression of MMP-9 was higher in DC (100%) than KCOT (69.9%) and was statistically significant ( P = .028). Conclusion: It was concluded that the loose connective tissue wall in KCOT is because of the inherent nature of the lesion that could facilitate its biologic behavior. If inflammation is present, this could further aggravate the tumorigenic behavior.

scholarly journals Distribution of fibroblast surface antigen in the developing chick embryo.

1975 ◽  
Vol 142 (1) ◽  
pp. 41-49 ◽  
Author(s):  
E Linder ◽  
A Vaheri ◽  
E Ruoslahti ◽  
J Wartiovaara
Keyword(s):  
Chick Embryo ◽  
Connective Tissue ◽  
Basement Membranes ◽  
Loose Connective Tissue ◽  
Extracellular Medium ◽  
Liver Sinusoids ◽  
Stage Of Development ◽  
Parenchymal Cells ◽  
Fibrillar Network

Fibroblast surface (SE) antigen is present in fibrillar surface structures of cultured normal fibroblasts, shed to the extracellular medium, and is also found in circulation (serum and plasma). Malignant fibroblasts (transformed by viruses) do not express SF antigen on the cell surface. In this study the in vivo differentiation and distribution of SF antigen has been investigated in the developing chick embryo using cryostat sections and immunofluorescence. The major findings were: (a) SF antigen was detectable in the loose connective tissue of very early (2-to 3-day old) embryos. (b) Condensation of SF antigen was seen in various boundary membranes such as the glomerular and tubular basement membranes of the kidney, the boundary membranes of the notochord, yolk sac, and vitelline membranes and liver sinusoids. (c) SF antigen was found to be cell-type specific. It was seen as a fibrillar network in the loose connective tissue of different organs but not in the parenchymal cells. It was not found in muscle cells at any stage of development. (d) The antigen was present in the undifferentiated mesenchymal cells of the kidney; but not found after their development into epithelial cells of the secretory tubules. (e) Both in vivo and in fibroblast cultures SF antigen was distributed as a fibrillar network. These data indicate that SF antigen is a "differentiation antigen" restricted to certain cells of mesenchymal origin and character, and that is accumulates in the connective tissue during embryogenesis.

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