scholarly journals Direct Detection of Toxic Contaminants in Minimally Processed Food Products Using Dendritic Surface-Enhanced Raman Scattering Substrates

Sensors ◽  
2018 ◽  
Vol 18 (8) ◽  
pp. 2726 ◽  
Author(s):  
Hannah Dies ◽  
Maria Siampani ◽  
Carlos Escobedo ◽  
Aristides Docoslis
Keyword(s):  
Raman Scattering ◽  
Limit Of Detection ◽  
Screening Method ◽  
Food Products ◽  
Surface Enhanced Raman Scattering ◽  
Liquid Food ◽  
Minimally Processed ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

We present a method for the surface-enhanced Raman scattering (SERS)-based detection of toxic contaminants in minimally processed liquid food products, through the use of a dendritic silver nanostructure, produced through electrokinetic assembly of nanoparticles from solution. The dendritic nanostructure is produced on the surface of a microelectrode chip, connected to an AC field with an imposed DC bias. We apply this chip for the detection of thiram, a toxic fruit pesticide, in apple juice, to a limit of detection of 115 ppb, with no sample preprocessing. We also apply the chip for the detection of melamine, a toxic contaminant/food additive, to a limit of detection of 1.5 ppm in milk and 105 ppb in infant formula. All the reported limits of detection are below the recommended safe limits in food products, rendering this technique useful as a screening method to identify liquid food with hazardous amounts of toxic contaminants.

Surface-Enhanced Raman Scattering Fiber-Optic Sensor

1990 ◽  
Vol 44 (1) ◽  
pp. 63-69 ◽  
Author(s):  
J. M. Bello ◽  
T. Vo-Dinh
Keyword(s):  
Raman Scattering ◽  
Fiber Optic ◽  
Limit Of Detection ◽  
Spectral Characteristics ◽  
Surface Enhanced Raman Scattering ◽  
Fiber Optic Sensor ◽  
Optic Sensor ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

A fiber-optic system was developed for exciting and collecting surface-enhanced Raman scattering (SERS) signals generated from a sensing plate tip having silver-coated microparticles deposited on a glass support. Various fiber parameters, such as fiber type, fiber-substrate geometry, and other experimental parameters, were investigated to obtain the optimum conditions for the SERS fiber-optic device. In addition, analytical figures of merit relevant to the performance of the SERS fiber-optic sensor, such as SERS spectral characteristics, reproducibility, linear dynamic range, and limit of detection, were also investigated.

scholarly journals Ultrasensitive surface-enhanced Raman scattering detection in common fluids

2015 ◽  
Vol 113 (2) ◽  
pp. 268-273 ◽  
Author(s):  
Shikuan Yang ◽  
Xianming Dai ◽  
Birgitt Boschitsch Stogin ◽  
Tak-Sing Wong
Keyword(s):  
Raman Scattering ◽  
Limit Of Detection ◽  
High Specificity ◽  
Surface Enhanced Raman Scattering ◽  
Mapping Technique ◽  
Quantitative Detection ◽  
Specificity And Sensitivity ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Detecting target analytes with high specificity and sensitivity in any fluid is of fundamental importance to analytical science and technology. Surface-enhanced Raman scattering (SERS) has proven to be capable of detecting single molecules with high specificity, but achieving single-molecule sensitivity in any highly diluted solutions remains a challenge. Here we demonstrate a universal platform that allows for the enrichment and delivery of analytes into the SERS-sensitive sites in both aqueous and nonaqueous fluids, and its subsequent quantitative detection of Rhodamine 6G (R6G) down to ∼75 fM level (10−15 mol⋅L−1). Our platform, termed slippery liquid-infused porous surface-enhanced Raman scattering (SLIPSERS), is based on a slippery, omniphobic substrate that enables the complete concentration of analytes and SERS substrates (e.g., Au nanoparticles) within an evaporating liquid droplet. Combining our SLIPSERS platform with a SERS mapping technique, we have systematically quantified the probability, p(c), of detecting R6G molecules at concentrations c ranging from 750 fM (p > 90%) down to 75 aM (10−18 mol⋅L−1) levels (p ≤ 1.4%). The ability to detect analytes down to attomolar level is the lowest limit of detection for any SERS-based detection reported thus far. We have shown that analytes present in liquid, solid, or air phases can be extracted using a suitable liquid solvent and subsequently detected through SLIPSERS. Based on this platform, we have further demonstrated ultrasensitive detection of chemical and biological molecules as well as environmental contaminants within a broad range of common fluids for potential applications related to analytical chemistry, molecular diagnostics, environmental monitoring, and national security.

scholarly journals Ag-Coated Cellulose Fibers as Surface-Enhanced Raman Scattering Substrates for Adsorptive Detection of Malachite Green

Materials ◽  
2018 ◽  
Vol 11 (7) ◽  
pp. 1197 ◽  
Author(s):  
Yudong Lu ◽  
Changji Wu ◽  
Yang Wu ◽  
Ruiyun You ◽  
Gang Lin ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Malachite Green ◽  
Dynamic Range ◽  
Limit Of Detection ◽  
Cellulose Fibers ◽  
Surface Enhanced Raman Scattering ◽  
Ag Nps ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Surface-enhanced Raman scattering (SERS) is a sensitive technique for the detection of low concentration analytes. In this study, we used cellulose fibers (CF) as the templates for the loading of silver nanoparticles (Ag NPs), and the obtained CF-Ag was applied in the detection of R6G and Malachite Green (MG) by surface-enhanced Raman scattering. The adsorption technique was employed in the sample preparation, and the optimal detecting status was identified in the dynamic range (sample status ranging from wet to dry) for different concentration of analytes. In comparison to Ag NPs, CF-Ag showed enhanced performance for adsorptive detection of Malachite Green, and the limit of detection was 5 × 10−12 M.

Surface-enhanced Raman scattering of uranyl in aqueous samples: implications for nuclear forensics and groundwater testing

2017 ◽  
Vol 9 (10) ◽  
pp. 1575-1579 ◽  
Author(s):  
M. J. Trujillo ◽  
D. M. Jenkins ◽  
J. A. Bradshaw ◽  
J. P. Camden
Keyword(s):  
Raman Scattering ◽  
Nuclear Forensics ◽  
Limit Of Detection ◽  
Surface Enhanced Raman Scattering ◽  
Uranyl Ions ◽  
Aqueous Samples ◽  
Silver Colloids ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

A surface-enhanced Raman scattering (SERS) method, based on functionalized silver colloids, is developed for the detection of uranyl ions that yields a limit of detection of 24 ppb.

scholarly journals Highly Reproducible Surface-Enhanced Raman Scattering Detection of Alternariol Using Silver-Embedded Silica Nanoparticles

Sensors ◽  
2020 ◽  
Vol 20 (12) ◽  
pp. 3523 ◽  
Author(s):  
Eunil Hahm ◽  
Yoon-Hee Kim ◽  
Xuan-Hung Pham ◽  
Bong-Hyun Jun
Keyword(s):  
Raman Scattering ◽  
Silica Nanoparticles ◽  
Ag Nanoparticles ◽  
Limit Of Detection ◽  
Surface Enhanced Raman Scattering ◽  
Sers Signal ◽  
Relative Standard ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Alternariol (AOH) is a mycotoxin from fungi that has been found in processed foods due to its high thermal stability. To address the complexity and costs of conventional AOH detection methods, we propose an alternative based on surface-enhanced Raman scattering (SERS) and specially designed nanoparticle substrate. Herein, silver-embedded silica (SiO2@Ag) nanoparticles with a highly reproducible SERS signal were successfully developed for detecting AOH. Silica nanoparticles (~145 nm) were used as a template to deposit silver nanoparticles (~17 nm), thereby generating SiO2@Ag. The SiO2@Ag nanoparticles showed a good linearity between SERS signal intensity and AOH concentrations from 16 to 1000 nM with a limit of detection of 4.83 nM. Additionally, the SERS signal of the SiO2@Ag nanoparticles was highly reproducible, with relative standard deviations of 2.33–5.95% in the AOH concentration range from 10 to 10,000 nM, demonstrating the reliability of the proposed SERS method.

scholarly journals Noble Metallic Pyramidal Substrate for Surface-Enhanced Raman Scattering Detection of Plasmid DNA Based on Template Stripping Method

Micromachines ◽  
2021 ◽  
Vol 12 (8) ◽  
pp. 923
Author(s):  
Wenjie Wu ◽  
Rui Li ◽  
Maodu Chen ◽  
Jiankang Li ◽  
Weishen Zhan ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Noble Metal ◽  
Plasmid Dna ◽  
Metal Film ◽  
Limit Of Detection ◽  
Surface Enhanced Raman Scattering ◽  
Sers Substrate ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

In this paper, a new method for manufacturing flexible and repeatable sensors made of silicon solar cells is reported. The method involves depositing the noble metal film directly onto the Si template and stripping out the substrate with a pyramid morphology by using an adhesive polymer. In order to evaluate the enhancement ability of the substrate, Rhodamine 6G (R6G) were used as surface-enhanced Raman scattering (SERS) probe molecules, and the results showed a high sensitivity and stability. The limit of detection was down to 10−12 M for R6G. The finite-difference time domain (FDTD) was used to reflect the distribution of the electromagnetic field, and the electric field was greatly enhanced on the surface of the inverted pyramidal substrate, especially in pits. The mechanism of Raman enhancement of two types of pyramidal SERS substrate, before and after stripping of the noble metal film, is discussed. By detecting low concentrations of plasmid DNA, the identification of seven characteristic peaks was successfully realized using a noble metallic pyramidal substrate.

Rapid Detection of Cypermethrin by Using Surface-Enhanced Raman Scattering Technique

2020 ◽  
Vol 853 ◽  
pp. 102-106
Author(s):  
Wipawanee Leung ◽  
Saksorn Limwichean ◽  
Noppadon Nuntawong ◽  
Pitak Eiamchai ◽  
Sukon Kalasung ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Rapid Detection ◽  
Limit Of Detection ◽  
Surface Enhanced Raman Scattering ◽  
Sers Substrate ◽  
Silver Nanorods ◽  
Raman Spectrometer ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Cypermethrin is a toxic pesticide in the pyrethroid group. A Surface Enhanced Raman Scattering (SERS) based sensor has been developed to achieve simple pesticide sensing. In this work, rapid detection of cypermethrin by using the handheld Raman spectroscopy coupled with SERS substrate was demonstrated. SERS-active silver nanorods substrate was used to enhance Raman signals of test samples. The effect of exposure time and drop volume of sample was studied for cypermethrin measurement. The results found that the silver nanorods substrate can be used to measure cypermethrin in the range of 10-6 to 10-3 M with a handheld Raman spectrometer. Furthermore, the Raman signal of cypermethrin was confirmed by measuring solid cypermethrin with the standard Raman spectrometer. SERS substrate was competent to detect cypermethrin with a limit of detection (LOD) of 10-6 M.

Optofluidic Surface Enhanced Raman Scattering Chip for Detection of Dengue Virus

2008 ◽  
Author(s):  
Yun Suk Huh ◽  
Aram J. Chung ◽  
Bernardo Cordovez ◽  
David Erickson
Keyword(s):  
Raman Scattering ◽  
Dengue Virus ◽  
Limit Of Detection ◽  
Surface Enhanced Raman Scattering ◽  
Virus Serotype ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Total Analysis ◽  
Enhanced Raman Scattering ◽  
On Chip

In this work we describe the development of an optofluidic device for surface enhanced Raman scattering (SERS) based detection of biological pathogens. The chip exploits the use of electro-active microwells which serve to both physically concentrate the Raman enhancers and to reduce the total analysis time through a unique electrokinetically driven on-chip mixing effect. To quantify the concentration performance of the device we use 44 nm polystyrene particles at low electric field strength (between 1.00–2.00 V) and demonstrate close to 90% concentration saturation within 2.5 s. We demonstrate the mixing capability through the enhanced detection of dengue virus serotype 2 (DENV-2). With DENV-2, we successfully detected the SERS signals with a limit of detection of 30 pM.

scholarly journals A Rapid Surface-Enhanced Raman Scattering (SERS) Method for Pb2+ Detection Using L-Cysteine-Modified Ag-Coated Au Nanoparticles with Core–Shell Nanostructure

Coatings ◽  
2018 ◽  
Vol 8 (11) ◽  
pp. 394 ◽  
Author(s):  
Zhou Xu ◽  
Linwei Zhang ◽  
Bo Mei ◽  
Jia Tu ◽  
Rong Wang ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Au Nanoparticles ◽  
Limit Of Detection ◽  
Pure Water ◽  
Surface Enhanced Raman Scattering ◽  
Noble Metal Nanoparticles ◽  
Core Shell ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

A rapid surface-enhanced Raman scattering (SERS) method for Pb2+ detection has been developed based on l-cysteine-modified Ag-coated Au nanoparticles with core-shell nanostructure. Specifically, l-cysteine-functionalized Au@Ag core-shell probes bearing Raman-labeling molecules (4-ATP) are used to detect Pb2+ upon the formation of nanoparticle aggregates. The proposed SERS-based method shows a linear range between 5 pM and 10 nM, with an unprecedented limit of detection (LOD) of 1 pM for Pb2+; this LOD shows the method to be a few orders of magnitude more sensitive than the typical colorimetric approach that is based on the aggregation of noble metal nanoparticles. Real water samples diluted with pure water have been successfully analyzed. This SERS-based assay may provide a general and simple approach for the detection of other metal ions of interest, and so could have wide-ranging applications in many areas.

scholarly journals AgNPs functionalized with dithizone for the detection of Hg2+ based on surface–enhanced Raman scattering spectroscopy

2022 ◽  
Author(s):  
Na Guo ◽  
Guangda Xu ◽  
Qijia Zhang ◽  
peng song ◽  
Lixin Xia
Keyword(s):  
Raman Scattering ◽  
Water Samples ◽  
Metal Ion ◽  
Limit Of Detection ◽  
Sample Pretreatment ◽  
Surface Enhanced Raman Scattering ◽  
Raman Scattering Spectroscopy ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Abstract Mercuric ion (Hg2+), a poisonous metal ion that remained in water ecosystems, can severely damage the human central and peripheral nervous system and kidneys. Consequently, rapid and highly sensitive methods to determine trace Hg2+ are meaningful to discuss. We have proposed a novel approach of surface-enhanced Raman scattering (SERS) for the quantitative analysis of Hg2+ in water samples using dithizone (DTZ) as a Raman reporter. DTZ-modified silver nanoparticles (AgNPs) produced a strong SERS signal. In the presence of Hg2+, the DTZ can capture Hg2+ composing a stable structure, resulting in DTZ leaving the surface of the AgNPs, with an accompanying decrease in the signal. The proposed SERS assay showed a linear range of 10−4–10−8 M, with a limit of detection of 9.83 × 10−9 M. The sensor has low detection cost, rapid detection speed, and uncomplicated sample pretreatment. Furthermore, this method can be successfully utilized to detect Hg2+rapidly in water samples, which sheds new light on the detection of Hg2+ in the environment.

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