scholarly journals Risk Factors for Herpes Zoster in Patients with Chronic Kidney Disease: A Case-Control Study

Vaccines ◽  
2021 ◽  
Vol 9 (9) ◽  
pp. 963
Author(s):  
Zhenxing Li ◽  
Qiao Wang ◽  
Jiahui Ma ◽  
Zhi Li ◽  
Dong Huang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Herpes Zoster ◽  
Kidney Disease ◽  
Odds Ratio ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Dialysis Therapy ◽  
Control Study

(1) Background: Chronic kidney disease (CKD) increases the susceptibility to the presence of herpes zoster (HZ). Little is known about the risk factors of HZ in CKD patients; (2) Methods: This is a case-control study. CKD patients diagnosed with HZ between January 2015 and June 2021 in a tertiary hospital were identified. One age- and gender- matched control was paired for each case, matched to the date of initial HZ diagnosis. Conditional multiple logistic regression was used to evaluate the risk factors associated with the presence of HZ; (3) Results: Forty-seven HZ patients and controls were identified. In general, about 73.40% (69 out of 94) patients were classified at IV to V stages of CKD. Immunosuppressive agents (p = 0.0012) and dialysis therapy (p = 0.021) were reported more frequently in the HZ cohort. Compared with the control group, the total white cell count and lymphocyte count were significantly lower in the HZ group (p value of 0.032 and 0.003, respectively). The conditional logistics regression model revealed that previous immunosuppressants administration (odds ratio: 10.861, 95% CI: 2.092~56.392, p = 0.005) and dialysis therapy (odds ratio: 3.293, 95% CI: 1.047~10.355, p = 0.041) were independent risk factors of HZ in the CKD population; (4) Conclusions: Dialysis and immunosuppressants therapy were associated with greater risk of HZ disease in CKD patients. Further guideline may highlight the necessity of zoster vaccine for patients with CKD, who undertake associated treatment.

scholarly journals Risk Factors for Herpes Zoster Infection in Patients With Chronic Kidney Disease: A Case-control Study

2021 ◽  
Author(s):  
Qiao Wang ◽  
Jiahui Ma ◽  
Zhenxing Li ◽  
Zhi Li ◽  
Dong Huang ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Herpes Zoster ◽  
Kidney Disease ◽  
Odds Ratio ◽  
Case Control Study ◽  
Immunosuppressive Agents ◽  
Tertiary Hospital ◽  
Case Control ◽  
Control Study

Abstract Background: Chronic kidney disease (CKD) increases the susceptibility to the infection of herpes zoster (HZ). Less is known about the risk factors of HZ in CKD patients.Methods and Participants: This is a case-control study. CKD patients diagnosed with HZ infection between January 2015 and October 2020 in a tertiary hospital were identified. One age- and gender- matched control was paired for each case, matched to the date of initial HZ diagnose. The uni- and multivariate analysis were used to evaluate the risk factors for development of HZ in CKD patients.Results: Forty-six HZ patients and controls were identified. In general, about 80% (72 out of 92) patients were classified at end-stage renal disease (ESRD, CKD Ⅳ to Ⅴ). Multivariate analyses revealed that immunosuppressive agents (odds ratio: 12.50, 95% CI: 1.53-102.26, P=0.021) and dialysis (odds ratio: 3.33, 95% CI: 1.13-9.78, P=0.029) were independent risk factors of HZ in patient with CKD. Conclusion: Immunosuppressive medication and dialysis were associated with HZ infection in CKD. Further guideline may highlight the necessity of zoster vaccine for patients with CKD, who undertake immunosuppressive or dialysis treatment.

scholarly journals Baked Food Consumption Is A Risk Factor for Chronic Kidney Disease: A 1:1 Paired Case-control Study

2020 ◽  
Author(s):  
Xiaoying Lai ◽  
Shiyu Zhou ◽  
Zewei Lin ◽  
Chuanjie Yan ◽  
Hong Zhu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Case Control Study ◽  
Case Control ◽  
Sleep Efficiency ◽  
Lifestyle Behaviors ◽  
Aquatic Product ◽  
Confounding Variables ◽  
Control Study

Abstract Background Chronic Kidney Disease (CKD) has become a global public health problem. Identifying the risk factors of CKD can provide strategies for the prevention of CKD. Studies showed that lifestyles play an important role in CKD, but the relationship between them remained unclear. Thus we aimed to explore the association of lifestyle behaviors (the dietary habits especially) with CKD. Methods A 1:1 matched case-control study including 1414 participates from the HUIQIAO health database system from Jan. 2015 to Dec. 2018 was conducted. Our main outcome measure was the diagnose of CKD, and exposures were lifestyle behaviors measured by a questionnaire. The anthropometric characteristics were included as confounding variables. Results We used conditional logistics regression to assess the odds ratios (ORs) and adjusted ORs for the risk factors. With the assumption of missing at random (MAR) pattern, the missing values of confounding variables and exposures were handled by multiple imputation. We found that lifestyle behaviors regarding skipping breakfast ≥ 3 times per week (1.672, 95% CI, 1.086–2.574), sleep efficiency ≤ 75% (1.633, 95% CI, 1.195–2.232), consuming baked food frequently (1.683, 95% CI, 1.163–2.434), proper intake of oil (0.789, 95% CI, 0.624–0.996), proper intake of aquatic product (0.732, 95% CI, 0.567–0.944), proper intake of soybean and nuts (0.625, 95% CI, 0.447–0.873) were associated with CKD. Conclusion These results suggest that moderate intake of soybean, nuts, and aquatic product, control oil intake, having breakfast at least 4 times per week, maintaining good sleep efficiency, and consuming less baked foods may contribute to prevent the development of CKD. Trial registration: This study is registered at http://www.chictr.org.cn (ChiCTR2000031864).

scholarly journals Risk Factors of Infantile Diarrhea (A Case-Control Study)

2019 ◽  
Vol 32 (5-6) ◽  
pp. 125-34
Author(s):  
Iskandar Z. Lubis
Keyword(s):  
Risk Factors ◽  
Odds Ratio ◽  
Case Control Study ◽  
Case Control ◽  
Bottle Feeding ◽  
Control Group ◽  
Case Group ◽  
Supplementary Food ◽  
Infantile Diarrhea ◽  
Control Study

From March thru April 1990 an unmatched case-control study had been conducted at the pediatric out-patient Clinic of Dr. Pirngadi Hospital Medan to assess risk factors of infantile diarrhea. The  study population were infants, aged younger than 21 months. The mothers of the infants were interviewed, using structured questionnaires. Sample size, calculated by means of formula, with 95 % level of confidence, 90 % power of study, 50% estimated proportion of exposure in the control-group and 2.0 estimated odds ratio, was 121. All infants with diarrhea were included in the case-group until a total number of 124 infants were reached. One control, an infant without diarrhea, was taken for each case from the nearest sequence of attendance after the case. A total of 20 risk factors were tested. Exposure was indicated from the last day before illness. Computerized statistical analysis was performed to calculate odds ratio, 95 % confidence interval and two tailed significance testing for qualitative dichotomic data by means of Chi square test. A total of nine factors were confirmed as risk factors of infantile diarrhea i.e mothers age than 20 years, working mother, not cleaning nipple before suckling the baby bottle feeding, having only one nursing botlle/teat, not ready for use nursing bottle/teat, giving left over supplementary food without reheating, no band-washing before giving supplementary food and malnutrition. The result of this study can be emphasized in health education, especially in diarrheal disease control of infancy; Further well-designed studies are needed.

scholarly journals Risk factors and their interaction on chronic kidney disease: A multi-centre case control study in Taiwan

2015 ◽  
Vol 16 (1) ◽  
Author(s):  
Sui-Lung Su ◽  
Chin Lin ◽  
SenYeong Kao ◽  
Chia-Chao Wu ◽  
Kuo-Cheng Lu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

To identify newer probable risk factors of chronic kidney disease in the indian population: A case–control study

2019 ◽  
Vol 17 (3) ◽  
pp. 55
Author(s):  
Saurabh Mamtani ◽  
Arti Muley ◽  
Mahek Mistry ◽  
Hiteshree Kantharia ◽  
VikasRaman Chandrakar
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Indian Population ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Calciphylaxis epidemiology, risk factors, treatment and survival among French chronic kidney disease patients: a case-control study

2020 ◽  
Vol 21 (1) ◽  
Author(s):  
Raphaël Gaisne ◽  
Morgane Péré ◽  
Victorio Menoyo ◽  
Maryvonne Hourmant ◽  
David Larmet-Burgeot
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Effect of Chronic Kidney Disease on Olfactory Function: A Case–Control Study

2021 ◽  
pp. 014556132199662
Author(s):  
T. Yusuf ◽  
Y. R. Raji ◽  
A. Daniel ◽  
O. T. Bamidele ◽  
A. J. Fasunla ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Case Control Study ◽  
Case Control ◽  
Olfactory Dysfunction ◽  
Olfactory Function ◽  
Control Group ◽  
Olfactory Pathway ◽  
Significant Difference ◽  
Control Study

Background: Olfactory function of patients with chronic kidney disease (CKD) has been found to be defective, and patients are often unaware of it. This predisposes them to malnutrition with consequence on health recovery and quality of life. Aim: To assess the olfactory function and determine the pattern of olfactory dysfunction in patients with CKD attending the University College Hospital, Ibadan. Materials and Methods: This was a prospective, hospital-based case–control study of adult patients with CKD. The control group were age- and sex-matched individuals without CKD. Olfactory threshold (OT), odor discrimination (OD), and odor identification (OI) tests were carried out in participants using the “Sniffin Sticks.” Results: There were 100 patients with CKD and 100 healthy controls, age ranges between 19 to 86 years (mean ± SD = 46.3 ± 13.9 years) and 20 to 85 years (mean ± SD = 43.4 ± 14.9 years), respectively. There was no statistically significant difference between cases and control gender distribution ( P = .57). The mean olfactory scores were significantly lower among the cases than control, OI 11.2 ± 2.3 and 13.1 ± 1.2 ( P < .001), OD 8.5 ± 2.4 and 10.9 ± 1.5 ( P < .001), OT 6.4 ± 2.5 and 9.6 ± 1.9 ( P < .001), and threshold discrimination and identification 26.0 ± 5.7 and 33.6 ± 3.3 ( P < .001), respectively. Prevalent olfactory dysfunction among patients with CKD was 77% (hyposmia 72%, anosmia 5%), and the control was 16% (all hyposmia; P < .001). Conclusion: There was high prevalence of olfactory dysfunction among patients with CKD, and the affectation is more at the central olfactory pathway.

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