scholarly journals Effectiveness of cetylpyridinium chloride, chlorhexidine gluconate, chlorine dioxide, and essential oils against F. nucleatum, P. gingivalis, S. mutans and S. sobrinus---a biofilm approach

2010 ◽  
Author(s):  
Kristafer Lee Adkins
Keyword(s):  
Essential Oils ◽  
Chlorine Dioxide ◽  
Cetylpyridinium Chloride ◽  
Chlorhexidine Gluconate

scholarly journals Effectiveness of Oral Antiseptics on Tooth Biofilm: A Study in vivo

2015 ◽  
Vol 16 (8) ◽  
pp. 674-678 ◽  
Author(s):  
Mateus Rodrigues Tonetto ◽  
Matheus Coelho Bandéca ◽  
Etevaldo Matos Maia Filho ◽  
José Carlos Elias Mouchrek Junior ◽  
Lívia Helena de Araújo Castro Nunes ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Active Ingredient ◽  
Cetylpyridinium Chloride ◽  
Chlorhexidine Gluconate ◽  
Blind Study ◽  
Plaque Index ◽  
The Mean ◽  
Bacterial Plaque

ABSTRACT Aim To evaluate the effectiveness of five different mouthwashes through measurement of the plaque index. Materials and methods Fifty subjects took part in this blind study, randomized into blocks of five groups according to the active ingredient of the mouthwash: CHX group (0.12% chlorhexidine gluconate), essential oils (EO) group, cetylpyridinium chloride (CPC) group, Tri group (triclosan) and Hamamelis virginiana (HV) group. All subjects were evaluated for a reduction in the bacterial plaque index at 7, 14 and 21 days. Results There was a significant reduction in the mean plaque index during the period of evaluation (p < 0.01), and the reduction during the period of evaluation was different between mouthwashes (p < 0.01). The reduction in the plaque index at the end of 21 days was, in decreasing order, CHX > EO > CPC > Tri > HV. Conclusion The reduction in the plaque index during the period of evaluation was different between the types of mouthwash. The mouthwash containing the active ingredient chlorhexidine was the most effective, followed by the essential oil, cetylpyridinium chloride, triclosan and H. virginiana. How to cite this article Junior Mouchrek JCE, Nunes LHAC, Arruda CS, Rizzi CC, Mouchrek AQS, Tavarez RRJ, Tonetto MR, Bandeca MC, Maia Filho EM. Effectiveness of Oral Antiseptics on Tooth Biofilm: A Study in vivo. J Contemp Dent Pract 2015;16(8):674-678.

scholarly journals Brief Report: The Virucidal Efficacy of Oral Rinse Components Against SARS-CoV-2 In Vitro

2020 ◽  
Author(s):  
Evelina Statkute ◽  
Anzelika Rubina ◽  
Valerie B O’Donnell ◽  
David W. Thomas ◽  
Richard J. Stanton
Keyword(s):  
Essential Oils ◽  
Povidone Iodine ◽  
Cetylpyridinium Chloride ◽  
Transmission Risk ◽  
Log10 Reduction ◽  
Live Virus ◽  
Oral Rinse ◽  
Virucidal Efficacy

AbstractThe ability of widely-available mouthwashes to inactivate SARS-CoV-2 in vitro was tested using a protocol capable of detecting a 5-log10 reduction in infectivity, under conditions mimicking the naso/oropharynx. During a 30 second exposure, two rinses containing cetylpyridinium-chloride and a third with ethanol/ethyl lauroyl arginate eliminated live virus to EN14476 standards (>4-log10 reduction), while others with ethanol/essential oils and povidone-iodine (PVP-I) eliminated virus by 2-3-log10. Chlorhexidine or ethanol alone displayed little or no ability to inactivate virus. Studies are warranted to determine whether these formulations can inactivate virus in the human oropharynx in vivo, and whether this might impact transmission risk.

Antibacterial and Antiplaque Effects of a Novel, Alcohol-Free Oral Rinse with Cetylpyridinium Chloride

2005 ◽  
Vol 6 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Jon Witt ◽  
Nivedita Ramji ◽  
Roger Gibb ◽  
John Dunavent ◽  
Janine Flood ◽  
...  
Keyword(s):  
Clinical Study ◽  
Essential Oils ◽  
Treatment Period ◽  
Antimicrobial Agents ◽  
Cetylpyridinium Chloride ◽  
Antibacterial Action ◽  
Oral Rinse ◽  
Whole Saliva

Abstract Antimicrobial agents are commonly incorporated into hygiene products for the treatment and prevention of plaque and gingivitis. Recently, a new alcohol-free rinse containing 0.07% cetylpyridinium chloride (CPC) in a high bioavailable matrix (Crest® Pro-Health Rinse) was introduced to provide antiplaque and antigingivitis benefits. This paper reviews results from an in vitro pre-clinical study and an in vivo clinical study evaluating the antibacterial and antiplaque benefits of this CPC rinse technology. In the in vitro experiment, a no-alcohol 0.065% high bioavailable CPC prototype rinse was evaluated for its hostility against a broad range of microorganisms commonly associated with plaque and gingivitis. The rinse demonstrated greater than 99% germ kill for all organisms tested individually as well as in whole saliva. The benefit of this antibacterial action on plaque inhibition was assessed in a clinical trial. A double-blinded, 3-period, 6-sequence crossover study was conducted evaluating the antiplaque effect of the novel 0.07% high bioavailable, alcohol-free CPC rinse versus a positive control (Listerine® Cool Mint containing essential oils) and a negative control (placebo CPC rinse). A modification of the Addy 4-day plaque model was used for this evaluation. Plaque was measured at baseline (Day 1) of each treatment period and at Day 4 using the Turesky modification of Quigley-Hein index. During the treatment period, subjects brushed only their lingual surfaces twice daily for up to 60 seconds. Following brushing, subjects used 20 mls of the mouthrinse product for 30 seconds in the morning and evening. Fifty-five subjects completed the study. For non-brushed sites, both the essential oils and CPC rinse exhibited a 25% reduction in plaque vs. placebo after four days of product usage, which was statistically significant (p < 0.0001). Both treatments also exhibited a statistically significant benefit versus placebo (p<0.0001) for brushed sites (>38% plaque reduction). These data support the antibacterial action of the high bioavailable, alcohol-free CPC rinse and demonstrate antiplaque effects for Crest Pro-Health Rinse that are “at least as good as” the leading essential oils antiseptic, making it well-suited for a broad range of patients, particularly those who are sensitive to products containing alcohol. Citation Witt J; Ramji N; Gibb R; Dunavent J; Flood J; Barnes J. Antibacterial and Antiplaque Effects of a Novel, Alcohol-Free Oral Rinse with Cetylpyridinium Chloride. J Contemp Dent Pract 2005 February; (6)1:001-009.

scholarly journals ESTUDO DOS ENXAGUATÓRIOS BUCAIS DISPONÍVEIS NAS DROGARIAS, FARMÁCIAS E SUPERMERCADOS NA CIDADE DO SALVADOR, BA

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Danilo Barral De Araújo ◽  
Elisângela De Jesus Campos ◽  
Gabriela Botelho Martins ◽  
Maria Thereza Barral Araújo ◽  
Midian Souza Assis ◽  
...  
Keyword(s):  
Essential Oils ◽  
Health Risks ◽  
Chemical Control ◽  
Cetylpyridinium Chloride ◽  
Economic Conditions ◽  
Chlorhexidine Digluconate ◽  
Access To Information ◽  
Active Ingredients ◽  
Bacterial Plaque ◽  
The City

Introduction: Often shown in chemical control of bacterial plaque and inflammatory and infectious processes installed in the oropharyngeal region the mouthwashes contain as active ingredients chlorhexidine, cetylpyridinium chloride, gantrez triclosan and essential oils. Objective: To survey the rinsing with antiseptic available in 2014 on a sample of pharmacies, drugstores and supermarkets located in the Administrative Regions IV and VIII – Salvador/BA, identifying the components, concentrations and dosages. Methodology: Four supermarkets and four pharmacies / drugstores installed in each of the Regions IV and VIII of the City of Salvador/BA were chosen at random, followed by a survey of mouthwashes with antiseptics available, coming from various manufacturers, and noted the data recorded on the label of the packages in order to access to pharmacological information on these commercial products. Results: The survey conducted in 16 commercial units visited revealed the predominance of basic active ingredients cetylpyridinium chloride (61.1%), chlorhexidine digluconate (11.1%), triclosan gantrez (7.4%), and essential oils (35,2%) or some association between these substances, as well as other components, concentrations and excipients. Conclusion: 1. The rinses available in stores installed in the Administrative Regions IV and VIII of Salvador, BA, correspond to a representative sample of other Regions, regardless of socio-economic conditions of the population of each; 2. Access to information on the label on the packaging of the active ingredients, other components, concentrations and excipients is extremely restricted, a condition that aggravates the health risks due to the omission of side effects. 3. The fact that rinses contain associated or isolated antiseptic substances - whether associated or isolated - predominate in shops, the products containing cetylpyridinium chloride (followed by essential oils), chlorhexidine digluconate and triclosan gantrez

Sign in / Sign up

Export Citation Format

Share Document