Methods of extracorporeal detoxification in the treatment of patients with acute necrotic pancreatitis and DIC

2020 ◽  
pp. 9-21
Author(s):  
G. V. Rodoman ◽  
T. I. Shalaeva ◽  
M. I. Aleksandrov

The article analyzes the results of treatment of patients with acute necrotic pancreatitis and DIC who underwent extracorporeal detoxification (ECD) with heparin anticoagulation. We performed a retrospective analysis of the medical records of such patients who were treated in Moscow Clinical Hospital No. 24 in 2016–2017. Disorders indicating the development of DIC were detected in 38 patients with acute necrotic pancreatitis, 13 of them underwent extracorporeal detoxification methods, in 25 patients ECD was not used. The effect of ECD on hemostasis and clinical outcomes was studied. A tendency towards the progression of coagulopathy and an increase in the risks of developing hemorrhagic syndrome, multiple organ failure and death during extracorporeal detoxification with heparin anticoagulation was revealed. The insufficiently large number of patients included in the study does not allow us to draw a final conclusion about the use of heparin anticoagulation ECD in patients with acute destructive pancreatitis who were initially showing the signs of consumption coagulopathy, but the data obtained cast a doubt on its feasibility. Further research is needed to make recommendations for the use of ECD in this category of patients.

2020 ◽  
pp. 61-63
Author(s):  
S. Sh. Kakvaeva ◽  
M. A. Magomedova ◽  
A. N. Dzhalilova

One of the most serious problems of modern medicine is sepsis. The number of patients undergoing this complication is 20–30 million (WHO) annually and has no tendency to decrease. Sepsis is characterized by severe multiple organ failure due to a violation of the response of the macroorganism to an infectious agent. Moreover, it is dangerous with high mortality. Sepsis often develops in patients with immunodeficiency conditions, which primarily include pregnant women. The article presents a clinical observation of a case of periostitis in a pregnant woman complicated by a septic state.


2019 ◽  
Vol 41 part 3 (2) ◽  
pp. 21-24
Author(s):  
N. N. Veligotskiy ◽  
A. S. Trushin ◽  
A. I. Seroshtanov ◽  
A. A. Sheptukha ◽  
I. Ye. Bugakov ◽  
...  

The complex treatment results of 127 patients with extensive purulent processes in diabetes mellitus that were treated in our clinic with ozone therapy and ultrasonic cavitations at 2001–2018 are presents. The problems of the course of the disease and the aggravating influence of the accompanying pathology on it are noted. The options improving the results of treatment considered.Keywords: phlegmon, small pelvis, diabetes mellitus, multiple organ failure, ozone therapy, cavitations.


2021 ◽  
Vol 49 (6) ◽  
pp. 030006052110261
Author(s):  
Yanxia Huang ◽  
Renjing Zhang ◽  
Mei Meng ◽  
Dechang Chen ◽  
Yunxin Deng

Diquat is a widely used herbicide that is substituted for paraquat. With paraquat off the market, cases of diquat poisoning have been gradually increasing. The kidney is the most frequently impaired organ in diquat poisoning. Few cases of multiple organ failure caused by diquat have been reported. We herein describe a 30-year-old man who orally ingested about 160 mL of enriched diquat. Despite aggressive treatment, the patient’s condition progressed to multiple organ failure and death. The pulmonary lesions in this patient were different from those previously reported. This patient did not die of renal failure but of severe respiratory failure. He exhibited three different stages of pulmonary disease. The lung lesions in this case were unique. We hope that doctors will pay more attention to the lung lesions in patients with diquat poisoning in future and find new treatment methods to save the lives of such patients.


Vascular ◽  
2021 ◽  
pp. 170853812199657
Author(s):  
Tiehao Wang ◽  
Jichun Zhao ◽  
Ding Yuan

Objectives Multiple organ failure is a rare manifestation of ilio-iliac arteriovenous fistula which can lead to a high rate of misdiagnosis and death. Methods We reported a 61-year-old man presenting with multiple organ failure rapidly after right lower limb swelling. Computed tomography angiography showed an ilio-iliac arteriovenous fistula caused by right common iliac artery aneurysm, and venous thrombosis of bilateral common iliac veins. A bifurcated stent-graft with coil embolization of right internal iliac artery was used for repair. Results The patient recovered rapidly and was discharged without complications. Although arteriovenous fistula persisted due to type II endoleak, aneurysm sac and inferior vena cava significantly shrunk at six months follow-up. Conclusions This report demonstrated that multiple organ failure may appear when the distal outflow tracts of arteriovenous fistula are obstructed. Moreover, endovascular repair is effective for reversal of multiple organ failure caused by arteriovenous fistula, even if arteriovenous fistula persists due to type II endoleak.


2021 ◽  
pp. 014556132110060
Author(s):  
Jérôme R. Lechien ◽  
Rémi Hervochon ◽  
Stéphane Hans

A 42-year-old man was referred for a week history of severe dysphagia, odynophagia, fever (39 °C), fatigue, abdominal pain, pharyngeal swelling, and multiple neck lymphadenopathies. The medical history reported a mild form of COVID-19 one month ago. The biology reported an unspecified inflammatory syndrome. The patient developed peritonitis, myocarditis, and hepatitis. A myocardium biopsy was performed. A diagnosis of Kawasaki-like disease (KLD) was performed. The occurrence of KLD in adults is rare but has to be known by otolaryngologists regarding the otolaryngological clinical presentation that may precede the multiple organ failure.


2009 ◽  
Vol 79 (6) ◽  
pp. 431-436 ◽  
Author(s):  
David C. Dewar ◽  
Peter Mackay ◽  
Zsolt Balogh

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