Diagnosis and Treatment of Anorectal Lesions in Crohn's Disease

2010 ◽  
Vol 26 (3) ◽  
pp. 190
Author(s):  
Youn-Jung Heo ◽  
Won-Kap Park ◽  
Jae-Cheol Kim ◽  
Jong-Kyun Lee ◽  
Kwang-Yeon Kim
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Diagnosis And Treatment

Postoperative Recurrence of Crohn's Disease: Pathophysiology, Diagnosis and Treatment

2018 ◽  
Vol 18 (12) ◽  
pp. 979-988 ◽  
Author(s):  
Antonio Di Sario ◽  
Paola Sassaroli ◽  
Luigi Daretti ◽  
Giulia Annulli ◽  
Laura Schiada ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Postoperative Recurrence ◽  
Diagnosis And Treatment

scholarly journals Upper Gastrointestinal Manifestations of Crohn’s Disease: Differential Diagnosis and Treatment of an Uncommon Presentation of Crohn’s Disease

2021 ◽  
Author(s):  
Ketan Mehta ◽  
Maria T Kurtz
Keyword(s):  
Differential Diagnosis ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Psychological Effects ◽  
Learning Objectives ◽  
Diagnosis And Treatment ◽  
Military Career ◽  
Uncommon Presentation ◽  
The Military ◽  
Upper Gastrointestinal

ABSTRACT Esophagogastroduodenoileal involvement of Crohn’s disease (CD) is uncommon; less than 5% of adult patients will suffer from this condition, although this diagnosis is likely underestimated given the lack of routine evaluation of the upper gastrointestinal tract in the absence of symptoms. An interesting differential, including sarcoidosis, eosinophilic gastroenteritis, tuberculosis, and Brunner’s gland hyperplasia, should be considered. The consequences of this diagnosis can have profound impacts on the military career of a soldier. Learning objectives of this case report include workup, differential, diagnosis, and treatment of esophagogastroduodenoileal involvement of CD, as well as discussing the psychological effects of this diagnosis and impact on an individual’s military career.

Roles of double-balloon endoscopy in the diagnosis and treatment of Crohn’s disease: a multicenter experience

2010 ◽  
Vol 45 (7) ◽  
pp. 713-720 ◽  
Author(s):  
Jumpei Kondo ◽  
Hideki Iijima ◽  
Takashi Abe ◽  
Masato Komori ◽  
Satoshi Hiyama ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Diagnosis And Treatment ◽  
Double Balloon Endoscopy ◽  
Double Balloon

scholarly journals Fructose and/or Sorbitol Intolerance in a Subgroup of Lactose Intolerant Patients

1994 ◽  
Vol 8 (6) ◽  
pp. 389-393 ◽  
Author(s):  
SR Mishkin ◽  
L Sablauskas ◽  
S Mishkin
Keyword(s):  
Crohn’S Disease ◽  
Small Bowel ◽  
Crohn's Disease ◽  
Clinical Characteristics ◽  
Lactose Intolerance ◽  
Diagnosis And Treatment ◽  
Enzyme Replacement ◽  
Foreign Travel ◽  
History Of

The diagnosis and treatment of lactose intolerance often does not resolve all the symptoms of postcibal bloating and flatulence. Included in this study were 104 lactose intolerant patients (71 female, 33 male) who complained of residual postcibal discomfort in spite of adherence to and benefit from appropriate measures for their documented lactose intolerance (at least 20 ppm H2after 25 g lactose as well as appropriate symptomatic discomfort). Clinical characteristics common to this group included: symptomatic diarrhea (12.5%), history of foreign travel (5.8%), endoscopic and pathological evidence of gastritis and helicobacter infection (19.2 and 8.7%, respectively), nonspecific abnormalities of small bowel follow-through (15.4%), Crohn’s disease (8.7%) and colonic cliverticulosis (14.4%). Intolerance co fructose (at least 10 ppm H2after 25 g fructose plus appropriate symptoms) or sorbitol (at least 10 ppm H2after 5 g sorbitol plus appropriate symptoms) was documented in 17.3 and 18.3%, respectively. Intolerance to both fructose and sorbicol (administered as separate challenges), more than twice as common as intolerance to either one alone, occurred in 41.4% and was independent of sex. In conclusion, additional carbohydrate intolerances contribute to postcibal discomfort in more than 75% of lactose intolerant patients who remain symptomatic in spite of adherence to appropriate measures for this condition. While 62% of all patients had benefited significantly (greater than 50%) from appropriate dietary measures and enzyme replacement for lactose intolerance, only 40% of those who were also fructose intolerant and 47% who were sorbitol intolerant benefited (greater than 50%) from appropriate dietary measures (no enzyme replacement yet available) for intolerance to these sugars.

scholarly journals SUBSTANTIATION OF DIAGNOSIS AND TREATMENT OF CHRONIC RECURRENT APHTHOUS STOMATITIS IN CROHN’S DISEASE

2020 ◽  
Vol 73 (3) ◽  
pp. 512-516
Author(s):  
Oksana Y. Feleshtynska ◽  
Olena O. Dyadyk
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Oral Mucosa ◽  
Morphological Study ◽  
Comparison Group ◽  
Granulomatous Inflammation ◽  
Main Group ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Diagnosis And Treatment

The aim: To substantiate the diagnosis and treatment of chronic recurrent aphthous stomatitis in Crohn’s disease. Materials and methods: The analysis of diagnostic and treatment of 52 patients with chronic recurrent aphthous stomatitis in Crohn’s disease (main group), mean age 31.8 + 2.3 was performed. The comparison group consisted of 50 patients with chronic recurrent aphthous stomatitis not associated with Crohn’s disease (mean age 34.7 + 1.8). Patients in both groups were studied for clinical manifestations, morphological and immunohistochemical studies the aphthae on the oral mucosa were performed. Results: An objective evaluation of the oral mucosa showed that the aphthae on the oral mucosa in patients of both groups did not differ visually. In the morphological study, the patients in the main group had granulomatous inflammation of the oral mucosa, characteristic of Crohn’s disease, while the patients in the comparison group had fibrinous inflammation. Immunohistochemical study of the cell infiltrate phenotype in the area of the lesion revealed that the patients in the main group there prevailed CD68+macrophages, the appearance of both intraepithelial and cell infiltrates of T-lymphocyte suppressors, which is characteristic of Crohn’s disease. Conclusions: Diagnosis of chronic recurrent aphthous stomatitis in Crohn’s disease is based on biopsy of the aphthae on the oral mucosa and their morphological examination, the results of which confirm the presence of granulomatous inflammation, with a large number of macrophages, the presence of T-lymphocytes, characteristic of Crohn’s disease, while recurrent aphthous stomatitis of another genesis morphologically detect fibrinous inflammation. The choice of therapeutic tactics for chronic recurrent aphthous stomatitis depends on the results of the morphological study. When granulomatous inflammation is detected in patients with chronic recurrent aphthous stomatitis, which is characteristic of Crohn’s disease, in addition to topical treatment of the oral mucosa, specific therapy with mesalazine drugs is prescribed.

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