Faculty Opinions recommendation of A mechanosensory complex that mediates the endothelial cell response to fluid shear stress.

2005 ◽  
Author(s):  
Christopher Marshall
Keyword(s):  
Shear Stress ◽  
Endothelial Cell ◽  
Cell Response ◽  
Fluid Shear Stress ◽  
Fluid Shear ◽  
Endothelial Cell Response

A mechanosensory complex that mediates the endothelial cell response to fluid shear stress

Nature ◽  
2005 ◽  
Vol 437 (7057) ◽  
pp. 426-431 ◽  
Author(s):  
Eleni Tzima ◽  
Mohamed Irani-Tehrani ◽  
William B. Kiosses ◽  
Elizabetta Dejana ◽  
David A. Schultz ◽  
...  
Keyword(s):  
Shear Stress ◽  
Endothelial Cell ◽  
Cell Response ◽  
Fluid Shear Stress ◽  
Fluid Shear ◽  
Endothelial Cell Response

T-786C Polymorphism of thenos-3Gene and the Endothelial Cell Response to Fluid Shear Stress—A Proteome Analysis

2009 ◽  
Vol 8 (6) ◽  
pp. 3161-3168 ◽  
Author(s):  
Abdul R. Asif ◽  
Michael Oellerich ◽  
Victor William Armstrong ◽  
Markus Hecker ◽  
Marco Cattaruzza
Keyword(s):  
Shear Stress ◽  
Endothelial Cell ◽  
Cell Response ◽  
Fluid Shear Stress ◽  
Proteome Analysis ◽  
Fluid Shear ◽  
Endothelial Cell Response

scholarly journals Turbulent fluid shear stress induces vascular endothelial cell turnover in vitro.

1986 ◽  
Vol 83 (7) ◽  
pp. 2114-2117 ◽  
Author(s):  
P. F. Davies ◽  
A. Remuzzi ◽  
E. J. Gordon ◽  
C. F. Dewey ◽  
M. A. Gimbrone
Keyword(s):  
Shear Stress ◽  
Endothelial Cell ◽  
Fluid Shear Stress ◽  
Vascular Endothelial Cell ◽  
Vascular Endothelial ◽  
Cell Turnover ◽  
Fluid Shear ◽  
Turbulent Fluid

Effects of Fluid Shear Stress on Endothelial Cell Invasion Into Three-Dimensional Matrices

2007 ◽  
Author(s):  
Hojin Kang ◽  
Kayla J. Bayless ◽  
Roland Kaunas
Keyword(s):  
Endothelial Cells ◽  
Shear Stress ◽  
Endothelial Cell ◽  
Cell Invasion ◽  
Fluid Shear Stress ◽  
Vascular Endothelial Cells ◽  
Umbilical Vein ◽  
Shear Stresses ◽  
Collagen Gels ◽  
Fluid Shear

We have previously developed a cell culture model to study the effects of angiogenic factors, such as sphingosine-1-phosphate (S1P), on the invasion of endothelial cells into the underlying extracellular matrix. In addition to biochemical stimuli, vascular endothelial cells are subjected to fluid shear stress due to blood flow. The present study is aimed at determining the effects of fluid shear stress on endothelial cell invasion into collagen gels. A device was constructed to apply well-defined fluid shear stresses to confluent human umbilical vein endothelial cells (HUVECs) seeded on collagen gels. Fluid shear stress induced significant increases in cell invasion with a maximal induction at ∼5 dyn/cm2. These results provide evidence that fluid shear stress is a significant stimulus for endothelial cell invasion and may play a role in regulating angiogenesis.

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