Faculty Opinions recommendation of Does EuroSCORE II perform better than its original versions? A multicentre validation study.

Author(s):  
Andrew Krahn ◽  
Manoj Obeyesekere
Keyword(s):  
2012 ◽  
Vol 75 (6) ◽  
pp. 1144-1147 ◽  
Author(s):  
YI CHEN ◽  
KATHY E. NOE ◽  
SANDRA THOMPSON ◽  
CAROL A. ELEMS ◽  
ERIC W. BROWN ◽  
...  

A revised U.S. Food and Drug Administration (FDA) method for the isolation and detection of Cronobacter from powdered infant formula was recently developed, which combines real-time PCR, chromogenic agars, and RAPID ID 32E biochemical tests. This method provides an expedient analysis within 24 to 48 h. A collaborative validation study involving four different laboratories was conducted to compare the revised FDA method with the reference FDA method using casein- and soy-based powdered infant formula inoculated with different Cronobacter strains. Valid results from 216 test portions and controls from collaborating laboratories were obtained and showed that the revised FDA method performed significantly better than the reference FDA method. Newly revised PCR protocols and VITEK 2 were also evaluated to be integrated into the complete detection procedure.


Author(s):  
John W. Grove ◽  
Adam C. Coleman ◽  
Carl E. Johnson ◽  
Ralph Menikoff

Abstract A computational verification and validation study of the Cyclops I experiment [1–7] was conducted using the Los Alamos Eulerian Applications code xRage [8]. The purpose of this study was to validate the Scaled Unified Reactive Front (SURF) plus (SURFplus) model for insensitive high explosives [9–12]. Diagnostics from the experiment included photon doppler velocimetry measurements of the encasing shell for the device and proton radiography photographs of the explosions. This data was compared to the xRage computed data and a convergence study of burn front evolution was conducted. We conclude that the SURFplus high explosive model does an excellent job at predicting the high explosive burn front velocity and shape with results that converge to the experimental data at rates near to or better than first order in most cases. Some companion verification metrics for the solution convergence are also described. These metrics show that the xRage computed solution for the high explosive burn front converges to first order or better, as consistent with the treatment of shock fronts in a higher order Godunov hydrodynamic solver as used in xRage.


2005 ◽  
Author(s):  
Vincent Magnotta

A novel fiber tracking algorithm (GTRACT) was developed to enhance tracking through ambiguous regions where cross fibers, fiber merging or fanning may be occurring. The software was developed using several cross platform open-source toolkits (ITK, VTK, and FLTK). The algorithm was evaluated using a freely available digital phantom dataset provided by King’s College London. The results show that the GTRACT algorithm performed significantly better than standard streamline approaches and is less affected by noise.


NeuroImage ◽  
2009 ◽  
Vol 47 ◽  
pp. S79
Author(s):  
X Kang ◽  
T Herron ◽  
D Woods

2015 ◽  
Vol 114 (8) ◽  
pp. 1304-1312 ◽  
Author(s):  
Laura Trijsburg ◽  
Jeanne H. M. de Vries ◽  
Hendriek C. Boshuizen ◽  
Paul J. M. Hulshof ◽  
Peter C. H. Hollman ◽  
...  

AbstractAs FFQ are subject to measurement error, associations between self-reported intake by FFQ and outcome measures should be adjusted by correction factors obtained from a validation study. Whether the correction is adequate depends on the characteristics of the reference method used in the validation study. Preferably, reference methods should (1) be unbiased and (2) have uncorrelated errors with those in the FFQ. The aim of the present study was to assess the validity of the duplicate portion (DP) technique as a reference method and compare its validity with that of a commonly used reference method, the 24 h recall (24hR), for protein, K and Na using urinary markers as the unbiased reference method. For 198 subjects, two DP, two FFQ, two urinary biomarkers and between one and fifteen 24hR (web based and/or telephone based) were collected within 1·5 years. Multivariate measurement error models were used to estimate bias, error correlations between FFQ and DP or 24hR, and attenuation factors of these methods. The DP was less influenced by proportional scaling bias (0·58 for protein, 0·72 for K and 0·52 for Na), and correlated errors between DP and FFQ were lowest (protein 0·28, K 0·17 and Na 0·19) compared with the 24hR. Attenuation factors (protein 0·74, K 0·54 and Na 0·43) also indicated that the DP performed better than the 24hR. Therefore, the DP is probably the best available reference method for FFQ validation for nutrients that currently have no generally accepted recovery biomarker.


2012 ◽  
Vol 34 (1) ◽  
pp. 22-29 ◽  
Author(s):  
F. Barili ◽  
D. Pacini ◽  
A. Capo ◽  
O. Rasovic ◽  
C. Grossi ◽  
...  
Keyword(s):  

2009 ◽  
Vol 26 (3) ◽  
pp. 107-113 ◽  
Author(s):  
John Fagan ◽  
Atif Ijaz ◽  
Alexia Papaconstantinou ◽  
Aideen Lynch ◽  
Helen O'Neill ◽  
...  

AbstractObjectives:Structured professional judgement is now the most widely accepted approach to clinical risk assessment and risk management. The Suicide Risk Assessment and Management Manual (S-RAMM) is a new structured professional judgement tool closely modelled on the HCR-20. This is the first prospective validation study for this instrument.Methods:Two post-membership registrars jointly interviewed 81 of 83 current inpatients to rate the S-RAMM. Two assistant psychologists independently rated the HCR-20, GAF and PANSS. All incidents of self-harm, attempted suicide, suicide and violence to others were collated from hospital reporting of critical incidents over the next six months supplemented by examination of other records.Results:For combined self-harm and suicide outcomes, the S-RAMM total score using the receiver operating characteristic had an area under the curve AUC=0.89, (95% CI 0.79 to 0.99). The S-RAMM performed as well for the prediction of self-harm and suicide as the HCR-20 did for violence, and better than measures of mental state (PANSS total score) and global function (GAF).Conclusions:The S-RAMM has better than minimum acceptable characteristics for use as a clinical or research tool for suicide risk assessment, and performs almost as well as the HCR-20 does for violence. Further prospective studies are now required, in other populations.


2005 ◽  
Vol 31 (11) ◽  
pp. 1434-1439 ◽  
Author(s):  
Anne-Lene Krogstad ◽  
Stefan Kazimierz Piechnik
Keyword(s):  

2012 ◽  
Vol 1 (33) ◽  
pp. 120 ◽  
Author(s):  
Dano Roelvink ◽  
Guus Stelling ◽  
Bas Hoonhout ◽  
Johan Risandi ◽  
Walter Jacobs ◽  
...  

The formulations of the 2DH process-based, nearshore morphological model XBeach were extended to allow for curvilinear grids using a finite volume approach. The formulations were tested for schematic cases such as a circular island and a field validation study was carried out for the case of storm erosion during a construction phase of the soft sea defense of the Maasvlakte-2 extension of Rotterdam port. It was found that the 2D curvilinear version performs significantly better than individual 1D runs. The overall skill of the 2D model for this case can be classified as 'reasonable' while the prediction of the erosion can be classified as 'good'.


2005 ◽  
Vol 31 (11) ◽  
pp. 1434-1439
Author(s):  
Anne-Lene Krogstad ◽  
Stefan Kazimierz Piechnik
Keyword(s):  

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