Faculty Opinions recommendation of Limited evidence: higher efficacy of nasal saline irrigation over nasal saline spray in chronic rhinosinusitis--an update and reanalysis of the evidence base.

2014 ◽  
Author(s):  
Devyani Lal ◽  
Rachel B Cain
Keyword(s):  
Chronic Rhinosinusitis ◽  
Evidence Base ◽  
Limited Evidence ◽  
Saline Irrigation ◽  
Nasal Saline Irrigation

Nasal Saline Irrigation for Chronic Rhinosinusitis

2010 ◽  
Vol 3 (3) ◽  
pp. 145-147 ◽  
Author(s):  
Vipan Gupta ◽  
Sunder Singh
Keyword(s):  
Mast Cell ◽  
Qualitative Study ◽  
Chronic Rhinosinusitis ◽  
Symptom Score ◽  
Control Group ◽  
Saline Irrigation ◽  
Common Disorder ◽  
Nasal Saline Irrigation ◽  
And Control ◽  
Group 1

Abstract Background Chronic rhinosinusitis (CRS) is a very common disorder in ENT practice. There are many modalities available for the treatment and control of symptoms of allergic rhinosinusitis, varying from antihistamines, corticosteroids, mast cell stabilizers in oral and topical formulations. Objective The present study was planned to see the influence of nasal saline irrigation on symptomatology of chronic rhinosinusitis. Design Qualitative study using a questionnaire. Methods Nasal saline irrigation (NSI) was advised to 53 patients twice a day along with anti-allergic treatment. The control group consists of 47 allergic patients who received only anti-allergic treatment. Results The symptom score significantly (p < 0.001) improved in the group 1 patients using nasal saline irrigation along with anti-allergic treatment. Conclusion the results of the study suggest that concomitant use of NSI with anti-allergic treatment gives much more satisfactory results than with only anti-allergic treatment in patients with chronic rhinosinusitis.

scholarly journals Combining antidepressants: a review of evidence

2009 ◽  
Vol 15 (2) ◽  
pp. 90-99 ◽  
Author(s):  
Lena Palaniyappan ◽  
Lisa Insole ◽  
Nicol Ferrier
Keyword(s):  
Side Effect ◽  
Evidence Base ◽  
Side Effect Profile ◽  
Combined Treatments ◽  
Limited Evidence ◽  
Additional Advantage ◽  
Treatment Approaches ◽  
The Uk

SummarySequenced (stepped) treatment approaches are widely endorsed in the management of depression. Combining antidepressants is a recognised step for those failing to respond to monotherapy. Despite the limited evidence base, this strategy is widely used by clinicians in practice. Not every combination used clinically has a sound neuropharmacological rationale and the use of such combinations may increase the side-effect burden without any additional advantage to the patient. Efficacy of various antidepressant combinations along with the data on side-effect profile and toxicity of such combined treatments are reviewed here. The different combinations are considered by each class of antidepressant available in the UK.

scholarly journals Preventive and therapeutic role of nasal irrigation in management of acute respiratory disease during COVID-19 pandemic and beyond

2021 ◽  
pp. 58-64
Author(s):  
V. M. Svistushkin ◽  
Zh. T. Mokoyan
Keyword(s):  
Respiratory Tract ◽  
Nasal Cavity ◽  
Distribution Area ◽  
Upper Respiratory Tract ◽  
Saline Irrigation ◽  
Nasal Irrigation ◽  
Wide Range ◽  
Upper Respiratory ◽  
Nasal Saline Irrigation ◽  
Tract Infections

It has long been known, that nasal saline irrigation is a safe and effective method, which is routinely prescribed by otorhinolaryngologists to prevent and to treat a wide range of pathologies. There are a lot of publications on different irrigation techniques and methods. This literature review discusses the key parameters of nasal irrigation, including tonicity, pH, and the additional components, and explains how they affect the effectiveness of the procedure. The vast majority of available publications did not found any possible changes in the effectiveness of solutions with different pH close to neutral meaning. Whereas, the volume of the irrigated solution, increases the efficiency of the irrigation in direct proportion. Thus, the largest distribution area of the solute is noted when washing with a large volume of liquid. Nasal saline irrigation is an effective treatment option for patients with several acute and chronic diseases and for postoperative care after rhinosurgery. Moreover, nasal irrigation might be used as an effective non-specific method for prevention of acute upper respiratory tract infections. Irrigation of the nasal cavity reduces the mucus viscosity and promotes its faster elimination, along with pathogens fixed in it. Additionally, irrigation with isotonic saline solutions increases the hydration of the underlying water base, which enhances the frequency of ciliary beat and reduces the concentration of local inflammatory mediators. COVID-19 pandemic situation due to lack of any specific antiviral drugs dictates the necessity of an effective non-specific preventive option, which could be introduced worldwide. The so-called full volume lavage of the nasal cavity allows for better cleaning of the nasal cavity and effective moisturizing of the mucous membrane. It is the timely cleansing and moisturizing that are most important for maintaining the normal activity of the local protective mechanisms of the upper respiratory tract.

Does Mobile Technology Have a Place in Differentiated Instruction?

2014 ◽  
pp. 132-149
Author(s):  
Therese M. Cumming
Keyword(s):  
Educational Technology ◽  
Instructional Design ◽  
Mobile Computing ◽  
Differentiated Instruction ◽  
Mobile Technology ◽  
Evidence Base ◽  
Mobile Technologies ◽  
Future Research ◽  
Inclusive Classroom ◽  
Limited Evidence

Although mobile technologies are relatively new, they have quickly become ubiquitous in education, despite a limited evidence base for their efficacy in instructional design. This chapter discusses differentiated instruction for the inclusive classroom and how this can be best accomplished using mobile technology as an educational tool. Using mobile computing devices such as the iPad in differentiated instruction has many advantages, but is not without challenges. Many of these challenges can be addressed using suggestions from previous research in the areas of differentiated instruction and educational technology. Future research is necessary to provide a solid evidence-base supporting the use of mobile technology with diverse learners in all levels of classroom instruction.

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