Faculty Opinions recommendation of Whole Body Vibration Therapy after Ischemia Reduces Brain Damage in Reproductively Senescent Female Rats.

A risk of ischemic stroke increases exponentially after menopause. Even a mild-ischemic stroke can result in increased frailty. Frailty is a state of increased vulnerability to adverse outcomes, which subsequently increases risk of cerebrovascular events and severe cognitive decline, particularly after menopause. Several interventions to reduce frailty and subsequent risk of stroke and cognitive decline have been proposed in laboratory animals and patients. One of them is whole body vibration (WBV). WBV improves brain hemodynamics and lessens frailty-related functional and cognitive deterioration. The goal of current study is to test the efficacy of WBV in reducing post-ischemic stroke frailty and brain damage in reproductively senescent female rats. Reproductively senescent Sprague–Dawley female rats were exposed to transient middle cerebral artery occlusion (tMCAO) and randomly assigned to either WBV or control groups. Animals placed in the WBV group underwent 30 days of WBV (40 Hz) treatment performed twice daily for 15 min each session for 5 days each week. The motor functions of animals belonging to both groups were tested intermittently and at the end of treatment period. Brains were then harvested for inflammatory markers and histopathological analysis. The results demonstrate a significant reduction in inflammatory markers, infarct volume, and significant increases in brain-derived neurotrophic factor and improvement in functional activity after tMCAO in middle-aged female rats that were treated with WBV as compared to the control group. Our results may help faster translation of the WBV intervention for improved outcome after stroke, particularly among frail women.

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Whole Body Vibration Therapy after Ischemia Reduces Brain Damage in Reproductively Senescent Female Rats

International Journal of Molecular Sciences ◽

10.3390/ijms19092749 ◽

2018 ◽

Vol 19 (9) ◽

pp. 2749 ◽

Cited By ~ 6

Author(s):

Ami Raval ◽

Marc Schatz ◽

Pallab Bhattacharya ◽

Nathan d’Adesky ◽

Tatjana Rundek ◽

...

Keyword(s):

Ischemic Stroke ◽

Cognitive Decline ◽

Brain Damage ◽

Inflammatory Markers ◽

Whole Body Vibration ◽

Female Rats ◽

Whole Body ◽

Laboratory Animals ◽

Histopathological Analysis ◽

Body Vibration

A risk of ischemic stroke increases exponentially after menopause. Even a mild-ischemic stroke can result in increased frailty. Frailty is a state of increased vulnerability to adverse outcomes, which subsequently increases risk of cerebrovascular events and severe cognitive decline, particularly after menopause. Several interventions to reduce frailty and subsequent risk of stroke and cognitive decline have been proposed in laboratory animals and patients. One of them is whole body vibration (WBV). WBV improves cerebral function and cognitive ability that deteriorates with increased frailty. The goal of the current study is to test the efficacy of WBV in reducing post-ischemic stroke frailty and brain damage in reproductively senescent female rats. Reproductively senescent Sprague-Dawley female rats were exposed to transient middle cerebral artery occlusion (tMCAO) and were randomly assigned to either WBV or no-WBV groups. Animals placed in the WBV group underwent 30 days of WBV (40 Hz) treatment performed twice daily for 15 min each session, 5 days each week. The motor functions of animals belonging to both groups were tested intermittently and at the end of the treatment period. Brains were then harvested for inflammatory markers and histopathological analysis. The results demonstrate a significant reduction in inflammatory markers and infarct volume with significant increases in brain-derived neurotrophic factor and improvement in functional activity after tMCAO in middle-aged female rats that were treated with WBV as compared to the no-WBV group. Our results may facilitate a faster translation of the WBV intervention for improved outcome after stroke, particularly among frail women.

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Whole body vibration therapy after ischemia reduces brain damage in reproductively senescent female rats

10.20944/preprints201807.0194.v2 ◽

2018 ◽

Author(s):

Ami P. Raval ◽

Marc Schatz ◽

Pallab Bhattacharya ◽

Nathan d’Adesky ◽

Tatjana Rundek ◽

...

Keyword(s):

Ischemic Stroke ◽

Cognitive Decline ◽

Brain Damage ◽

Inflammatory Markers ◽

Whole Body Vibration ◽

Female Rats ◽

Whole Body ◽

Control Group ◽

Histopathological Analysis ◽

Body Vibration

A risk of ischemic stroke increases exponentially after menopause. Even a mild-ischemic stroke can result in increased frailty. Frailty is a state of increased vulnerability to adverse outcomes, which subsequently increases risk of cerebrovascular events and severe cognitive decline, particularly after menopause. Several interventions to reduce frailty and subsequent risk of stroke and cognitive decline have been proposed in laboratory animals and patients. One of them is whole body vibration (WBV). WBV recuperates cerebral function and cognitive ability that deteriorates with increased frailty. The goal of the current study is to test the efficacy of WBV in reducing post-ischemic stroke frailty and brain damage in reproductively senescent female rats. Reproductively senescent Sprague–Dawley female rats were exposed to transient middle cerebral artery occlusion (tMCAO) and randomly assigned to either WBV or control groups. Animals placed in the WBV group underwent 30 days of WBV (40 Hz) treatment performed twice daily for 15 min each session, 5 days each week. The motor functions of animals belonging to both groups were tested intermittently and at the end of treatment period. Brains were then harvested for inflammatory markers and histopathological analysis. The results demonstrate a significant reduction in inflammatory markers and infarct volume with significant increases in brain-derived neurotrophic factor and improvement in functional activity after tMCAO in middle-aged female rats that were treated with WBV as compared to the control group. Our results may facilitate a faster translation of the WBV intervention for improved outcome after stroke, particularly among frail women.

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Whole body vibration therapy in fracture prevention among adults with chronic disease

World Journal of Orthopedics ◽

10.5312/wjo.v1.i1.20 ◽

2010 ◽

Vol 1 (1) ◽

pp. 20 ◽

Cited By ~ 13

Author(s):

Marco YC Pang

Keyword(s):

Chronic Disease ◽

Whole Body Vibration ◽

Fracture Prevention ◽

Whole Body ◽

Body Vibration ◽

Vibration Therapy

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Comparison of the effect of whole-body vibration therapy versus conventional therapy on functional balance of patients with Parkinson’s disease: adding a mixed group

Acta Neurologica Belgica ◽

10.1007/s13760-020-01439-7 ◽

2020 ◽

Author(s):

Eduardo Guadarrama-Molina ◽

Carlos Enrique Barrón-Gámez ◽

Ingrid Estrada-Bellmann ◽

Jesús D. Meléndez-Flores ◽

Paola Ramírez-Castañeda ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Conventional Therapy ◽

Whole Body Vibration ◽

Whole Body ◽

Mixed Group ◽

Body Vibration ◽

Functional Balance ◽

Vibration Therapy

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Does whole body vibration therapy assist in reducing fat mass or treating obesity in healthy overweight and obese adults? A systematic review and meta-analyses

Disability and Rehabilitation ◽

10.1080/09638288.2019.1688871 ◽

2019 ◽

pp. 1-13 ◽

Cited By ~ 1

Author(s):

S. Mohammad Alavinia ◽

Maryam Omidvar ◽

B. Catharine Craven

Keyword(s):

Systematic Review ◽

Fat Mass ◽

Whole Body Vibration ◽

Whole Body ◽

Obese Adults ◽

Body Vibration ◽

Vibration Therapy ◽

Meta Analyses

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Effects of Whole-Body Vibration Therapy in Patients with Fibromyalgia: A Systematic Literature Review

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2015/719082 ◽

2015 ◽

Vol 2015 ◽

pp. 1-11 ◽

Cited By ~ 9

Author(s):

Daniel Collado-Mateo ◽

Jose C. Adsuar ◽

Pedro R. Olivares ◽

Borja del Pozo-Cruz ◽

Jose A. Parraca ◽

...

Keyword(s):

Quality Of Life ◽

Literature Review ◽

Whole Body Vibration ◽

Whole Body ◽

Health Related Quality ◽

Body Vibration ◽

Vibration Therapy ◽

Related Quality ◽

Health Related

Objective. To review the literature on the effects of whole-body vibration therapy in patients with fibromyalgia.Design. Systematic literature review.Patients. Patients with fibromyalgia.Methods. An electronic search of the literature in four medical databases was performed to identify studies on whole-body vibration therapy that were published up to the 15th of January 2015.Results. Eight articles satisfied the inclusion and exclusion criteria and were analysed. According to the Dutch CBO guidelines, all selected trials had a B level of evidence. The main outcomes that were measured were balance, fatigue, disability index, health-related quality of life, and pain. Whole-body vibration appeared to improve the outcomes, especially balance and disability index.Conclusion. Whole-body vibration could be an adequate treatment for fibromyalgia as a main therapy or added to a physical exercise programme as it could improve balance, disability index, health-related quality of life, fatigue, and pain. However, this conclusion must be treated with caution because the paucity of trials and the marked differences between existing trials in terms of protocol, intervention, and measurement tools hampered the comparison of the trials.

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