scholarly journals Clinical and Pathological Features of Lipid Storage Myopathy; A Retrospective Study of a Large Group from Iran

2020 ◽  
Vol 8 (1) ◽  
pp. 26-29
Author(s):  
Yalda Nilipour ◽  
Parveneh Karimzadeh ◽  
Shahriar Nafissi ◽  
Mohammad Mahdi Taghdiri ◽  
Hedyeh Saneifard ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Lipid Storage ◽  
Pathological Features ◽  
Lipid Storage Myopathy ◽  
Large Group ◽  
Clinical And Pathological Features

scholarly journals A Clinical and Pathological Study of Kikuchi–Fujimoto Disease in A University Hospital in Saudi Arabia

2018 ◽  
Vol 25 (1) ◽  
pp. 23-29
Author(s):  
Fahad A. Alghamdi ◽  
Mohammed S. Abdelwahed ◽  
Abdulaziz Alghamdi ◽  
Hani z. Marzouki ◽  
Ghadeer A. Mokhtar ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Retrospective Study ◽  
Histopathological Examination ◽  
Complete Recovery ◽  
Benign Disease ◽  
University Hospital ◽  
Pathological Features ◽  
Pathological Study ◽  
King Abdulaziz University ◽  
Clinical And Pathological Features

Kikuchi–Fujimoto disease is a benign disease of self-limiting course characterized by lymphadenopathy that is often mistaken clinically as lymphoma or infectious lymphadenitis. To prevent such a mistake, a clinical and pathological correlation is recommended. In this retrospective study, we are documenting the clinical and pathological features of this disease through the last 15 years (2001-2016) in King Abdulaziz University Hospital; and comparing results with that of international findings. From a total number of 1805 lymph nodes sent for histopathological examination during that period, only 9 cases had been diagnosed as Kikuchi–Fujimoto disease. Three (33%) cases were 20 years old and under; five (56%) cases were in the ages between 20 to 40 years old and only one (11%) was above 40 years old. Eight (89%) cases were females. Regarding the outcome, all cases showed complete recovery and there was no recurrence. Only two histological phases were seen, namely proliferative and necrotizing phases.  

P0136COMPARISON OF SECONDARY IGA NEPHROPATHY OF ANKYLOSING SPONDYLITIS AND PRIMARY IGA NEPHROPATHY IN CLINICAL AND PATHOLOGICAL FEATURES

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Qin Xue ◽  
Guang Li Zhang ◽  
Zebo Tian
Keyword(s):  
Retrospective Study ◽  
Ankylosing Spondylitis ◽  
Iga Nephropathy ◽  
Interstitial Fibrosis ◽  
Renal Involvement ◽  
Control Group ◽  
Pathological Features ◽  
Tubular Atrophy ◽  
The Difference ◽  
Clinical And Pathological Features

Abstract Background and Aims Renal involvement is one of the most common extra-articular complications caused by ankylosing spondylitis (AS). The main pathological manifestation is secondary IgA nephropathy(SIgAN) in Chinese AS patients. The difference between SIgAN and primary IgAN (PIgAN) remains unclear due to the lack of cases. Therefore, the aim of this retrospective study was to compare the clinical and pathological features of SIgAN of AS (SIgAN-AS) and PIgAN, to detect the pathogenesis of SIgAN Method Clinical characteristics and pathological data were collected in patients who were diagnosed with IgAN by renal biopsy in our hospital from Jan 2008 to Oct 2018. Patients with SIgAN-AS were recruited by the ratio 1:5 of patients with primary IgAN as the control group in the study. Fifteen patients with SIgAN-AS and Seventy-five patients with PIgAN were enrolled in this retrospective study. Results There were 15 cases in AS group, including 13 male and 2 female. The cohort of 75 patients with PIgAN included 34 male and 41 female. There were more males in AS group 13/15 (86.7%) vs 37/75(49.3%) ,P < 0.05. Compared with PIgAN patients, SIgAN-AS patients had higher incidences of hematuria( 13/15(86.7%)vs 44/75 (58.7%) , P < 0.05), lower levels of 24-hour urinary protein(0.85±0.68 vs 1.57±1.54g, P < 0.05), but higher levels of eGFR (CKD-MDRD formula) (117.60±37.33 vs 85.35±31.36, P < 0.05),eGFR (CKD-EPI formula) (128.01±41.58 vs 92.75±36.09, P < 0.05), Albumin (44.67±3.48 vs 41.09±7.07 g/L, P < 0.05) ESR (43.20 ±33.94 vs 18.79±16.26mm/h, P < 0.001) , and CRP (21.19±30.61 vs 2.11±4.58mg/L, P < 0.001) . From the perspective of renal pathology of PIgAN, SIgA-AS patients had fewer incidences of renal tubular atrophy / interstitial fibrosis of nephropathy (P <0.05). The immunohistostaining analysis showed higher incidences of dominant deposits of single IgA in mesangial cell area (P < 0.05). Conclusion Patients with SIgAN-AS is more common in male and display a milder progression than those with primary IgAN. Majority of the SIgAN-AS can be improved with early intervention.

scholarly journals CLINICOPATHOLOGICAL PROFILES OF EMERGENCY COLO-RECTAL CANCER SURGICAL CASES – PRELIMINARY REPORT OF A RETROSPECTIVE OBSERVATIONAL STUDY

2019 ◽  
Vol 5 (4) ◽  
pp. 204-214
Author(s):  
G. Andrei ◽  
B. Dumitriu ◽  
M. Beuran
Keyword(s):  
Colorectal Cancer ◽  
Rectal Cancer ◽  
Retrospective Study ◽  
Observational Study ◽  
Preliminary Report ◽  
Retrospective Observational Study ◽  
Pathological Features ◽  
Emergency Presentation ◽  
Perforated Colorectal Cancer ◽  
Clinical And Pathological Features

We present a preliminary report of an observational retrospective study of clinical and pathological features of emergency colorectal cancer (CCR) aiming to identify specific profiles of patients according to gender, age, and residence. This analysis would contribute to better understanding surgical emergency presentation and for identification of those characteristics that are essential for both reducing emergency CCR incidence and for improving the management of such cases. A number of 159 patients that underwent surgery for obstructive, bleeding and perforated colorectal cancer between January 2015 and September 2017 were selected to be included in the study. The results obtained by analyzing available data collected from the observation charts, surgery protocols, histopathological protocols were then compared with those in the literature.

scholarly journals Clinical and pathological features of Merkel cell carcinoma: A 4-year follow-up observational retrospective study in Spain

2022 ◽  
Vol 76 ◽  
pp. 102081
Author(s):  
Juan José Ríos-Martín ◽  
Nuria Rodriguez-Salas ◽  
Francisco Javier Vázquez-Doval ◽  
Beatriz Llombart ◽  
Nohelia Rojas-Ferrer ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Cell Carcinoma ◽  
Merkel Cell Carcinoma ◽  
Merkel Cell ◽  
Pathological Features ◽  
Clinical And Pathological Features

Cannabis-associated arteritis

VASA ◽  
2010 ◽  
Vol 39 (1) ◽  
pp. 43-53 ◽  
Author(s):  
Grotenhermen
Keyword(s):  
Systematic Review ◽  
Case Reports ◽  
Case Series ◽  
Cardiovascular Effects ◽  
Causative Factor ◽  
Cannabis Use ◽  
Thromboangiitis Obliterans ◽  
Pathological Features ◽  
Scientific Support ◽  
Clinical And Pathological Features

Background: To investigate the hypothesis that cases of arteritis similar to thromboangiitis obliterans (TAO) and associated with the use of cannabis were caused by cannabis or THC (dronabinol), or that cannabis use is a co-factor of TAO. Patients and methods: A systematic review on case reports and the literature on so-called cannabis arteritis, TAO, and cardiovascular effects of cannabinoids was conducted. Results: Fifteen reports with 57 cases of an arteritis associated with the use of cannabis and two additional case series of TAO, in which some patients also used cannabis, were identified. Clinical and pathological features of cannabis-associated arteritis do not differ from TAO and the major risk factor of TAO, tobacco use, was present in most, if not in all of these cases. The proposed pathophysiological mechanisms for the development of an arteritis by cannabis use are not substantiated. Conclusions: The hypothesis of cannabis being a causative factor or co-factor of TAO or an arteritis similar to TAO is not supported by the available evidence. The use of the term “cannabis arteritis” should be avoided until or unless more convincing scientific support is forthcoming.

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