scholarly journals Glucose transporters in kidney; the role of gender and diabetes mellitus

2021 ◽  
Vol 11 (1) ◽  
pp. e3-e3
Author(s):  
Fatemeh Kharazmi ◽  
Hajaralsadat Hosseini Dastgerdi ◽  
Shadan Saberi ◽  
Maryam Maleki ◽  
Nepton Soltani ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Glucose Transport ◽  
Sex Hormones ◽  
Developmental Process ◽  
Short Review ◽  
Experimental Results ◽  
Kidney Functions ◽  
Structure And Functions ◽  
Data Banks

Sex hormones affect the developmental process and play important roles in the kidney’s structure and functions. Clinical and experimental results have indicated that kidney functions are different between the genders, and they may be associated with the sex hormones, which regulate the expression and action of transporters in the nephron. In the current short review, the data banks including PubMed, Google Scholar, and Scopus were reviewed to achieve the published related articles regarding the role of gender and diabetes mellitus in glucose transport in renal system.

The protective effect of diabetes mellitus against prostate cancer: Role of sex hormones

The Prostate ◽  
2009 ◽  
Vol 69 (16) ◽  
pp. 1744-1750 ◽  
Author(s):  
N. Baradaran ◽  
H. Ahmadi ◽  
S. Salem ◽  
M. Lotfi ◽  
Y. Jahani ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Diabetes Mellitus ◽  
Protective Effect ◽  
Sex Hormones

scholarly journals The effects of coordination zinc compound on glucose uptake and the activity of tissue pyruvate dehydrogenase in rats with experimental diabetes mellitus

2002 ◽  
Vol 48 (6) ◽  
pp. 48-50
Author(s):  
A. A. Samigzhonov ◽  
M. Zh. Ergasheva ◽  
T. S. Saatov
Keyword(s):  
Diabetes Mellitus ◽  
Glucose Transport ◽  
Pyruvate Dehydrogenase ◽  
Skeletal Muscles ◽  
Experimental Diabetes ◽  
Experimental Diabetes Mellitus ◽  
Zinc Compounds ◽  
Skeletal Muscle Mitochondria ◽  
Zinc Compound

Zinc compounds were examined for their effects on the transport of glucose through the membrane and on the activity of pyruvate dehydrogenase of mitochondria of the hearts and skeletal muscles from rats with experimental diabetes mellitus. The objects of the investigations were the rat diaphragm, cardiac and skeletal muscle mitochondria. The aim of the investigation was to study the effect of the coordination zinc compound piracine on the transport of glucose in the diaphragm and on the activity of pyruvate dehydrogenase of the hearts and skeletal muscles from rats with experimental diabetes mellitus. Experimental diabetes mellitus was induced by intraperitoneal alloxan hydrate during fasting. The investigation established that piracine exerted a stimulating effect on glucose transport in experimental diabetes. With the coordination zinc compound, there was an increase in the activity of pyruvate dehydrogenase, which is lowered in diabetes. The findings provide again evidence for the role of zinc ions in glucose transport and oxidation.

Role of Glucose Transport in the Postreceptor Defect of Non-insulin-dependent Diabetes Mellitus

Diabetes ◽  
1982 ◽  
Vol 31 (11) ◽  
pp. 1016-1022 ◽  
Author(s):  
T. P. Ciaraldi ◽  
O. G. Kolterman ◽  
J. A. Scarlett ◽  
M. Kao ◽  
J. M. Olefsky
Keyword(s):  
Diabetes Mellitus ◽  
Glucose Transport ◽  
Insulin Dependent Diabetes Mellitus ◽  
Insulin Dependent Diabetes ◽  
Dependent Diabetes Mellitus ◽  
Insulin Dependent

POPDC proteins and cardiac function

2019 ◽  
Vol 47 (5) ◽  
pp. 1393-1404 ◽  
Author(s):  
Thomas Brand
Keyword(s):  
Potential Role ◽  
Striated Muscle ◽  
Short Review ◽  
Effector Proteins ◽  
Muscle Disease ◽  
Disease Genes ◽  
Protein Protein Interaction ◽  
Interaction Partners ◽  
And Function

Abstract The Popeye domain-containing gene family encodes a novel class of cAMP effector proteins in striated muscle tissue. In this short review, we first introduce the protein family and discuss their structure and function with an emphasis on their role in cyclic AMP signalling. Another focus of this review is the recently discovered role of POPDC genes as striated muscle disease genes, which have been associated with cardiac arrhythmia and muscular dystrophy. The pathological phenotypes observed in patients will be compared with phenotypes present in null and knockin mutations in zebrafish and mouse. A number of protein–protein interaction partners have been discovered and the potential role of POPDC proteins to control the subcellular localization and function of these interacting proteins will be discussed. Finally, we outline several areas, where research is urgently needed.

Role of the Structural Characteristics of Dendrimers in the Manifestation of the Antiamyloid Properties

INEOS OPEN ◽  
2020 ◽  
Vol 3 ◽  
Author(s):  
S. A. Sorokina ◽  
◽  
Yu. Yu. Stroilova ◽  
V. I. Muronets ◽  
Z. B. Shifrina ◽  
...  
Keyword(s):  
Neurodegenerative Diseases ◽  
Structural Characteristics ◽  
Short Review ◽  
External Factors ◽  
Amyloid Aggregation ◽  
Amyloid Proteins ◽  
Molecular Parameters ◽  
Amyloid Aggregates ◽  
Aggregation Processes

Among the compounds able to efficiently inhibit the amyloid aggregation of proteins and decompose the amyloid aggregates that cause neurodegenerative diseases, of particular interest are dendrimers, which represent individual macromolecules with the hypercrosslinked architectures and given molecular parameters. This short review outlines the peculiarities of the antiamyloid activity of dendrimers and discusses the effect of dendrimer structures and external factors on their antiamyloid properties. The potential of application of dendrimers in further investigations on the aggregation processes of amyloid proteins as the compounds that exhibit the remarkable antiamyloid activity is evaluated.

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