scholarly journals Комплексный анализ применения фитопрепарата «пародонтоцид» в консервативном лечении больных хроническим генерализованным пародонтитом легкой степени

A comprehensive clinical and laboratory analysis of the use of the phytoremedy «Parodontocide» in the complex treatment of chronic periodontitis was carried out. «Parodontocide» contains sage oil, peppermint oil, sage oil, clove oil, allantoin, phenyl salicylate and it demonstrates a pronounced anti-inflammatory and repairing effect. It was well tolerated by the majority of patients, practically causing no adverse reactions and complications in comparison with other medications. That's precisely why «Parodontocide» can be used in a comprehensive treatment program for mild chronic periodontitis and in patients with intolerance to synthetic antiseptics as a part of monotherapy.

2020 ◽  
Vol 25 (2) ◽  
pp. 97-100
Author(s):  
A. K. Iordanishvili ◽  
V. A. Guk ◽  
A. A. Golovko

Relevance. The success of treatment of periodontal diseases directly depends on the patient’s response to the therapy, therefore, the characteristics of the person’s personal characteristics can affect both the effectiveness of treatment and the prevention of relapse of the disease.Purpose. To study the features of the internal picture of the disease in the process of complex treatment of adult patients suffering from chronic generalized periodontitis.Materials and methods. The generally accepted comprehensive treatment of chronic generalized periodontitis in 69 middle-aged and elderly men was carried out taking into account the personal response of patients Solovyov «Psychosensory-anatomical-functional maladaptation syndrome».Results. When patients were discharged from the hospital, there was a difference in the phenomena of maladaptation among the elderly and middle-aged: in middle-aged people, sufficient adaptation to the conditions of existence was determined; in elderly people, due to the existing comorbid pathology, a state of maladaptation was diagnosed, which was caused by the presence of complaints of defects in the dentition.Conclusion. In elderly people, as soon as possible after completion of treatment in a hospital, dental rehabilitation cannot be considered completed, which requires the adoption of organizational measures for their timely provision of dentures.


2021 ◽  
Vol 13 (4) ◽  
Author(s):  
Samuel Sarmiento Doncel ◽  
Gina Alejandra Diaz Mosquera ◽  
Javier Mauricio Cortes ◽  
Nelson Ramirez ◽  
Francisco Javier Meza ◽  
...  

Introduction: In recent decades, hemophilia A treatment has been focused on body weight, without taking pharmacokinetic parameters into account. Previous research has shown that the individual pharmacokinetic response is more effective in predicting the required dose of clotting factor. We want to evaluate the impact on reducing the frequency of bleeding in patients treated with recombinant factor VIII, based on a personalized comprehensive management program.   Objective: Our aim was to compare the results of a standard comprehensive treatment program (stage I) vs. a personalized pharmacokinetic - based treatment program (stage II) in a cohort of 60 patients with severe hemophilia without inhibitors.   Results:The median age was 15.5 years (3 - 68). The ABR was 1.03 (62 episodes) in the first stage and 0.58 (35 episodes) in the second one, (p = 0.004). By type of bleeding, the impact of the intervention differs significantly in spontaneous bleeding (p = 0.007) and a 73% reduction in the first stage. There were no significant differences in traumatic bleeding.   Conclusions: The use of pharmacokinetics for personalized dosing of patients with severe hemophilia A, significantly reduces ABR and spontaneous bleeding, improving the patient's quality of life and costs for the health system.


2020 ◽  
Vol 73 (3) ◽  
pp. 521-524
Author(s):  
Orest M. Chemerys ◽  
Olena V. Katelian ◽  
Sergii D. Khimich ◽  
Igor V. Stoianovskyi

The aim: Elaboration of the complex program of diagnostics and treatment of the polytraumatized overweight patients. Materials and methods: Clinical material was composed of 64 patients with the combined body trauma who suffered from II-III grade obesity. Results: Main principles of rendering the aid to the polytraumatized overweight patients included the pathophysiological and topographic features of the group. The obtained study results confirmed the credible difference of the traumatic disease progress in the patients with the normal weight and overweight patients which was the basis of our differential complex treatment program. The treatment tactics also had certain characteristics connected with the obesity. The development of RDS syndrome is a typical stage of the traumatic disease during the blunt thoracal trauma in case of obesity. The programmed and urgent relaparotomy, as a method of the stage treatment in the present group of patients, is the integral component of the blunt abdominal injury in case of obesity. Conclusions: The study results proved that our complex program of diagnostics and treatment of the polytraumatized patients shall be basic for the patients with II-III grade obesity.


2021 ◽  
Vol 6 (5) ◽  
pp. 38-44
Author(s):  
O. D. Saliuk ◽  
◽  
P. H. Gerasimchuk ◽  
L. O. Zaitsev ◽  
I. I. Samoilenko ◽  
...  

In this article the review of foreign and domestic literary sources, which are devoted to the actual problem of modern dentistry – the treatment of inflammatory diseases of periodontal tissues: gingivitis and periodontitis are presented. The complex approach to their treatment involves the appointment of a significant amount of pharmacotherapeutic drugs. Therapeutic failures and iatrogenic complications have led to the fact that today the interests of doctors and population to medicinal products significantly increased. The purpose of the study is to analyze the data of scientific literature on the use of plant-based medicinal products for the treatment of periodontal inflammatory diseases over the past 10 years. Materials and methods. Comprehensive and systematic analysis of literature. Review and discussion. The analysis of information sources on the use of plant-based medicinal products in dentistry both independently and in the composition of medical and prophylactic means has established that the modern assortment of plant-based preparations in the pharmaceutical market of Ukraine to a certain extent is limited. The emergence of new plant-based species that have been tested in conditions of experimental pathology and require an evidence-based clinical base is noted. The composition of plant-based preparations used for the treatment of inflammatory periodontal diseases include vitamins, biologically active substances, glycosides, alkaloids, in connection with a wide range of action: antiseptic, anti-inflammatory, regenerating, hemostatic, antioxidative. The data on plant-based preparations that are most often used such as chamomile extracts, calendula, hypericum, plantain, kalanchoe, aloe, eucalyptus, milfoil, nettle, calamus and plant-based species are summarized. The medicinal agents considered are mainly recommended for local treatment of periodontal diseases in the form of dental care means, mouth rinse, gel, chewing gum, herbal liquer. It is known that the complex treatment of periodontal diseases includes a general influence on the body. The properties of green tea with its wide range of actions are investigated. With antioxidant properties, it can be a healthy alternative for controlling destructive changes in periodontal diseases. Attention is drawn to the proposed unique natural complex “Resverazin” due to a wide range of pharmacological action, low toxicity and relative safety. The drug produces antioxidant, anti-inflammatory, immune stimulating, vasodilative, neuroprotective action. Conclusion. Based on the literature analysis, it can be concluded that the accumulated experimental and clinical data on the therapeutic properties of plants prove perspective of their use in the complex treatment of inflammatory periodontal diseases. Future studies are mandatory for further confirmation of the effectiveness of these medicinal plants


2021 ◽  
Author(s):  
Takayuki Harada ◽  
Toshiaki Baba ◽  
Tomohiro Shirasaka ◽  
Shogo Kanamori

Abstract Background: The Philippines is one of the most severely affected countries by the methamphetamine epidemic in the world. The government launched a war on drugs policy to counter the situation in the country. However, brutality against drug users was criticized internationally. Thus, we have developed a comprehensive treatment program for methamphetamine users based on cognitive-behavioral therapy (CBT) and are going to evaluate its effectiveness. If its effectiveness is demonstrated, it will be helpful to implement much more effective and humane approaches to drug issues in the Philippines.Methods: Methamphetamine users who are admitted to government-run rehabilitation facilities are recruited and are randomly assigned either to the CBT-based treatment program or existing therapeutic community (TC)-based treatment. The CBT treatment program was developed based on the Matrix model considering the cultural and social factors in the Philippines. After 6-months treatment, participants will be followed up for 3 months and drug use (urine testing) and other psychological variables including craving, coping skills, and well-being will be compared.Ethics and dissemination Informed consent will be obtained from study participants prior to study participation. Ethical approval was obtained from research ethics review boards in both countries. This study was approved by Single Joint Research Ethics Board of the Department of Health, Republic of the Philippines (SJREB-2019-27) and the University of Tsukuba Faculty of Human Sciences Ethics Committee (T2019-70). 1). Potential participants will be given a summary of the study and a consent form. The consent form is signed and dated by participants prior to their study participation. Findings of this study will be submitted for publication in international scientific peer-reviewed journals and be presented at academic conferences.Trial registration number: UMIN Clinical Trials Registry JPRN-UMIN000038597. Registered on 15 November 2019. Protocol version February 13, 2020 ver.1


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