THE ESSENCE OF THE COMPLEX PROGRAM FOR THE PREVENTION OF DESTRUCTIVE INFLUENCE OF THE INTERNET ENVIRONMENT ON THE STUDENT YOUTH

The spread of information technology in all spheres of life has a significant impact on the socialization and social adaptation of an individual. It also creates risks of negative impact on the psychological well-being, health and even life of the younger generation. The modern information age raises the problem of the formation of students ability to self-education, their competence work with different types of information and critical thinking skills. The purpose of the article is to reveal the essence of the program for the prevention of destructive influence of the Internet environment on the student youth in the activities of social service centers. Using the method of analysis of the scientific literature, the content of the basic concepts of research is clarified. To substantiate the essence and features of prevention programs of destructive influence of the Internet environment on the student youth we used methods of systematization and generalization. In the article the author considers the state of prevention of destructive influence of the Internet environment in Ukraine and reveals the essence of the complex program for the prevention of such influence on student youth in the activity of the centers of social services. The author analyzes the current state of preventive activities; defines the concept of «prevention of destructive influence». The paper describes the purpose and objectives of preventive work, the structural components of the program, reveals their content. The program is aimed at personal development, motivation for active involvement in the process of planning further life, providing opportunities to master the skills of counteracting destructive influence, critical thinking.

Problems of Detecting Economic Crimes in Ukraine (1996–2021)

Criminological investigation of correlation between corruption and organized economic crime testifies that organized crime and corruption first of all endangers national security of Ukraine, its further development, ensuring constitutional system, proper functioning of all political-economic system. That is why not accidentally the Decrees of the President of Ukraine “On Complex Earmarked for a Specific Purpose Program for Fighting Criminality” and “On Complex Program in Preventing Criminality” define fighting organized crime and corruption in an economic sphere as one of priority directions. Detecting of organized crimes committed under not obvious circumstances is a complicated and multifactored. The necessity of quick and correct solving informational, methodological, tactical, psychological, technical and many other issues predetermined active participation of inquiry and search workers, the Security Service, militia, its operative detachments, the Procurator’s Office, experts, professionals, and the public. That is why a complex approach to fighting crime, including economic one, needs further development, also improvement in co-operation between all law-enforcement and controlling organs is needed. The work in this direction should be considered one of priorities for state organs nowadays and in future.

Prevention of The Development of Postoperative Complications and Their Treatment in The Surgery of Duedenal Purpose

The authors analyze various degrees of physiological anastomositis in 131 patients, and conclude that for the treatment of late anastomositis after surgical interventions on the stomach and duodenum, it is recommended to include the laser action of the anastomosis zone with two types of low-energy lasers in the complex program. The authors argue that the combined use of low-energy laser exposure through endoscopic and percutaneous irradiation will improve the effectiveness of the treatment of late anastomositis.

Genomic imprinting in mouse blastocysts is predominantly associated with H3K27me3

In mammalian genomes, differentially methylated regions (DMRs) and histone marks including trimethylation of histone 3 lysine 27 (H3K27me3) at imprinted genes are asymmetrically inherited to control parentally-biased gene expression. However, neither parent-of-origin-specific transcription nor imprints have been comprehensively mapped at the blastocyst stage of preimplantation development. Here, we address this by integrating transcriptomic and epigenomic approaches in mouse preimplantation embryos. We find that seventy-one genes exhibit previously unreported parent-of-origin-specific expression in blastocysts (nBiX: novel blastocyst-imprinted expressed). Uniparental expression of nBiX genes disappears soon after implantation. Micro-whole-genome bisulfite sequencing (µWGBS) of individual uniparental blastocysts detects 859 DMRs. We further find that 16% of nBiX genes are associated with a DMR, whereas most are associated with parentally-biased H3K27me3, suggesting a role for Polycomb-mediated imprinting in blastocysts. nBiX genes are clustered: five clusters contained at least one published imprinted gene, and five clusters exclusively contained nBiX genes. These data suggest that early development undergoes a complex program of stage-specific imprinting involving different tiers of regulation.

Intellectual Grid Modulation and Monitoring

In this article design of communicational devices and approbation of Intellectual Grid technologies are considered. As well the characteristics of the functional properties of Intellectual Grid technology are presented. Model of the electrical enginering system in complex program MATLAB (Simulink) are developed.

Complex program for the prevention of the development and progression of refractive errors in school year children

Aim: to develop a complex preventive and therapeutic program for refractive errors in school year children. Patients and Methods: 1,760 pupils of elementary, secondary, and high school of eight schools of Almaty (1,302 pupils of gymnasiums and 458 pupils of general education schools and sport boarding school) were examined. The 1st step was a preventive screening. The 2nd step was a distant interactive screening by teachers. The 3rd step was an eye examination of schoolers with low vision. The efficacy of the detection of visual impairments in schoolers during preventive and distant computer screening was compared. In addition, significant indicators for visual impairment monitoring in schoolers were identified. A "Program for the Prevention of the Development and Progression of Refractive Errors in Schoolchildren" was developed. To evaluate its efficacy, 140 pupils of general education schools with refractive errors and 1,302 pupils of gymnasiums with refractive errors or their high risk underwent eye examinations. In addition, to compare the effect of wearing glasses/contact lenses with full correction on the quality of life, 31 schoolers aged 12–17 with refractive errors were selected. Results: the rate of visual impairments was 28.4% among the pupils of general education schools and 31.3% among the pupils of gymnasiums. The most common refractive error was myopia (46.9% and 65.4%, respectively). As children moved through their school carrier, the proportion of myopia tended to increase. Accommodative dysfunction ranked second 48.5% and 29.7%, respectively). Time spent on distant screening was twice less compared to time spent on preventive screening. Visual acuity, cycloplegic refraction, reserves of relative accommodation, and axial length (measured by ultrasound) were indicators of visual impairments in children during monitoring. Poor general health was reported in 33% of children who wear glasses and 15% of children who wear contact lenses. Keywords: refractive errors, myopia, accommodation, schoolchildren, distant screening, prevention, vision correction with contact lenses. For citation: Botabekova T.K., Aldasheva N.A., Abdullina V.R. et al. Complex program for the prevention of the development and progression of refractive errors in school year children. Russian Journal of Clinical Ophthalmology. 2021;21(3):135–142 (in Russ.). DOI: 10.32364/2311- 7729-2021-21-3-135-142.