scholarly journals Historical aspects of the development of the theory of ventricular preexcitation

2021 ◽  
Vol 28 (4) ◽  
pp. 45-51
Author(s):  
G. R. Matsonashvili ◽  
T. R. Matsonashvili ◽  
S. Yu. Serguladze ◽  
V. G. Suladze ◽  
R. H. Faizaliev

The paper conducts a review of the literature on the problem of cognition of the nature of the syndrome of preexcitation of the ventricles. Despite the data of early publications, supporting the theory of bypass as a substrate of preexcitation, disputes and searches for the nature of this clinical syndrome continued until 1970, until surgical procedures and the first electrophysiological studies confirmed the “bypass” of the normal conducting system. Article describes the chronology of events related to the understanding of the syndrome, which bears the name Wolff-Parkinson-White.

2009 ◽  
Vol 123 (11) ◽  
Author(s):  
G X Papacharalampous ◽  
L Manolopoulos ◽  
S Korres ◽  
C Dicoglou ◽  
A Bibas

AbstractBackground:Adult laryngeal rhabdomyosarcomas are rare tumours commonly treated by laryngectomy.Case report:We present a case of subglottic laryngeal rhabdomyosarcoma in an elderly woman, treated by endoscopic resection.Conclusion:Despite the fact that this tumour is traditionally treated aggressively, this approach is not supported by the literature. Due to the varying biological behaviour of this tumour in adults, we believe that conservative surgical procedures or combination therapies should be preferred, rather than total laryngectomy.


2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Kwo Wei David Ho ◽  
Nivedita U. Jerath

The clinical effect of T118M variant of the PMP22 gene has been controversial. Several studies have suggested that it may be autosomal recessive, partial loss of function, or a benign variant. Here we report three cases in further support that the T118M variant of the PMP22 gene is a partial loss of function variant. These three unrelated cases were heterozygotes with the T118M variant of the PMP22 gene. All three cases presented with painful peripheral neuropathy and varying degrees of Charcot-Marie-Tooth exam features. Electrophysiological studies revealed polyneuropathy with axonal and demyelinating features in one case, but there were minimal electrophysiological changes in the other two cases. We propose that the T118M variant can cause painful peripheral neuropathy, which may be an underrecognized feature of this variant.


2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Leema Reddy Peddareddygari ◽  
Kinsi Oberoi ◽  
Raji P. Grewal

Congenital insensitivity to pain (CIP) is a rare autosomal recessive genetic disease caused by mutations in theSCN9Agene. We report a patient with the clinical features consistent with CIP in whom we detected a novel homozygous G2755T mutation in exon 15 of this gene. Routine electrophysiological studies are typically normal in patients with CIP. In our patient, these studies were abnormal and could represent the consequences of secondary complications of cervical and lumbosacral spine disease and associated severe Charcot’s joints.


1980 ◽  
Vol 88 (2) ◽  
pp. 146-153 ◽  
Author(s):  
Mamdouh S. Bahna ◽  
Paul H. Ward ◽  
Horst R. Konrad

Rhinocerebral mucormycosis, a highly lethal fungal infection of the head and neck, is commonly recognized by its classic appearance. Two cases of this newly recognized clinical syndrome with isolated unilateral peripheral cranial nerve V, VI, VII, IX, X, XI, and XII palsies and initial sparing of the eighth cranial nerve are presented. Examination revealed that each patient had ulceration of the nasopharynx and osteitis of the base of the skull. Nose, orbits, paranasal sinuses, and intracranial nervous systems were initially spared. The cause of this obscure cranial nerve paralysis was diagnosed from biopsy specimens of the nasopharyngeal tissues and the demonstration of nonseptate hyphae. Review of the literature did not indicate that this syndrome had previously been recognized. The name nasopharyngeal mucormycotic osteitis is suggested.


Author(s):  
Greta Lisa Carlin ◽  
Barbara Bodner-Adler ◽  
Heinrich Husslein ◽  
Magdalena Ritter ◽  
Wolfgang Umek

Abstract Introduction and hypothesis Hysterectomy is one of the most commonly performed gynecological surgical procedures. One of the long-term risks associated with hysterectomy is the occurrence of pelvic organ prolapse (POP). To prevent post-hysterectomy POP, several suspension procedures are routinely performed at the time of hysterectomy. We performed a systematic review of published data in order to define the most effective surgical procedures for the prevention of post-hysterectomy POP. Methods We performed a systematic review of the literature by searching PubMed, the Cochrane Library, EMBASE, Ovid MEDLINE, and clinicaltrials.gov up to 24 May 2020. The search strategy included the keywords hysterectomy, post-hysterectomy, prolapse, colposuspension, culdoplasty, McCall, and combinations thereof. The inclusion criterion was a surgical procedure at the time of hysterectomy to prevent de novo POP. The outcome was incidence of post-hysterectomy POP. Results Six out of 553 retrieved studies met the methodological criteria for complete analysis. In this review, 719 women aged over 18 years were included. Only 2 studies were designed as prospective trials; however, only 1 compared women undergoing a procedure at the time of hysterectomy with controls. The prevalence of post-hysterectomy prolapse varied from 0% to 39%. Conclusion A systematic review of published literature suggests that performing variations of McCall culdoplasty at the time of hysterectomy might be the most effective prophylactic surgical procedure for preventing post-hysterectomy pelvic organ prolapse.


Perfusion ◽  
2021 ◽  
pp. 026765912110265
Author(s):  
Kyriakos Anastasiadis ◽  
Polychronis Antonitsis ◽  
Christos Asteriou ◽  
Apostolos Deliopoulos ◽  
Helena Argiriadou

Introduction: Despite extensive evidence that shows clinical of superiority of MiECC, worldwide penetration remains low due to concerns regarding air handling and volume management in the context of a closed system. The purpose of this study is to thoroughly investigate perfusion safety and technical feasibility of performing all cardiac surgical procedures with modular (hybrid) MiECC, as experienced from the perfusionist’s perspective. Methods: We retrospectively reviewed perfusion charts of consecutive adult patients undergoing all types of elective, urgent, and emergency cardiac surgery under modular MiECC. The primary outcome measure was perfusion safety and technical feasibility, as evidenced in the need for conversion from a closed to an open circuit. A systematic review of the literature was conducted aiming to ultimately clarify whether there are any safety issues regarding MiECC technology. Results: We challenged modular MiECC use in a series of 403 consecutive patients of whom a significant proportion (111/403; 28%) underwent complex surgery including reoperations (4%), emergency repair of acute type A aortic dissection and composite aortic surgery (1.7%). Technical success rate was 100%. Conversion to an open circuit was required in 18/396 patients (4.5%), excluding procedures performed under circulatory arrest. Open configuration accounted for 40% ± 21% of total procedural perfusion time and was related to significant hemodilution and increase in peak lactate levels. Systematic review revealed that safety of the procedure challenged originated from a single report, while no clinical adverse event related to MiECC was identified. Conclusions: Use of modular MiECC secures safety and ensures technical feasibility in all cardiac surgical procedures. It represents a type III active closed system, while its stand-by component is reserved for a small (<5%) proportion of procedures and for a partial procedural time. Thus, it eliminates any safety concern regarding air handling and volume management, while it overcomes any unexpected intraoperative scenario.


2011 ◽  
Vol 2011 ◽  
pp. 1-7 ◽  
Author(s):  
Jason Khoury ◽  
Grant Townsend

Anaesthesia of structures innervated by the mandibular nerve is necessary to provide adequate pain control when performing dental and localised surgical procedures. To date, numerous techniques have been described and, although many of these methods are not used routinely, there are some situations where their application may be indicated. Patient factors as well as anatomical variability of the mandibular nerve and associated structures dictate that no one technique can be universally applied with a 100% success rate. This fact has led to a proliferation of alternative techniques that have appeared in the literature. This selective review of the literature provides a brief description of the different techniques available to the clinician as well as the underlying anatomy which is fundamental to successfully anaesthetising the mandibular nerve.


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