Mucociliary Clearance of Maxillary Sinus Mucosa before and after Endoscopic Sinus Surgery

Functional endoscopic sinus surgery concentrates primarily on the removal of ostiomeatal complex disease. When required, maxillary sinus ostioplasty is performed. However, surgical widening of a sinus ostium is contrary to common precepts. A study therefore was performed to reevaluate the effects of antrostomies and of intrasinus mucosal removal. Widening of the natural ostium, a separate antrostomy at some distance from the ostium, or radical mucosal removal was performed on 30 rabbits. Fifteen sinuses were used as controls. After 6 to 8 weeks the status of the sinus mucosa and mucociliary clearance was studied. The study confirmed that mucociliary clearance continued toward the natural ostium following inferior antrostomy. Following widening of the natural ostium, mucociliary clearance through the ostium redeveloped in 11 of 18 sinuses but was typically imperfect. There were no cases of ostial closure; however, the incidence of infection was significantly higher in all three experimental groups than in the control group.

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Ultrastructural ciliary changes of maxillary sinus mucosa following functional endoscopic sinus surgery: an image analysis quantitative study

The Journal of Laryngology & Otology ◽

10.1258/00222150360600878 ◽

2003 ◽

Vol 117 (4) ◽

pp. 273-279 ◽

Cited By ~ 9

Author(s):

Ahmed Bassiouny ◽

Ahmed M. Atef ◽

Mahmoud Abdel Raouf ◽

Safaa Mohamed Nasr ◽

Magdy Nasr ◽

...

Keyword(s):

Image Analysis ◽

Maxillary Sinus ◽

Endoscopic Sinus Surgery ◽

Quantitative Methods ◽

Maxillary Sinusitis ◽

Functional Endoscopic Sinus Surgery ◽

University Hospital ◽

Sinus Surgery ◽

Chronic Maxillary Sinusitis ◽

Sinus Mucosa

This was a study of the effect of functional endoscopic sinus surgery (FESS) on the ciliary regeneration of maxillary sinus mucosa in patients with chronic maxillary sinusitis, using objective quantitative methods. Twenty specimens from the mucosa of both the superolateral wall and the ostium of the maxillary sinus were sampled during FESS and then six to 12 months later. They were light examined first by light microscopy and then by scanning electron microscopy in combination with image analysis software in order to study the cilia under higher magnification and to calculate proportion of the field that was ciliated. Samples were taken and studied at Cairo University hospital. This study showed that the maxillary sinus mucosa in chronic sinusitis is capable of regeneration and could return towards normal with the improvement of ventilation and drainage of the maxillary sinus following FESS. There were no significant changes in the degree of glandular hyperplasia, goblet cells or pathological glands after surgery.

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Normalization of maxillary sinus mucosa after functional endoscopic sinus surgery in pediatric chronic sinusitis

International Journal of Pediatric Otorhinolaryngology ◽

10.1016/j.ijporl.2005.03.031 ◽

2005 ◽

Vol 69 (9) ◽

pp. 1219-1223 ◽

Cited By ~ 7

Author(s):

Hung-Meng Huang ◽

Hey-Ping Lee ◽

Chia-Ming Liu ◽

Kai-Nan Lin

Keyword(s):

Maxillary Sinus ◽

Endoscopic Sinus Surgery ◽

Chronic Sinusitis ◽

Functional Endoscopic Sinus Surgery ◽

Sinus Surgery ◽

Sinus Mucosa

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Histological Evaluation of Maxillary Sinus Mucosa after Functional Endoscopic Sinus Surgery

American Journal of Rhinology ◽

10.2500/ajr.2007.21.3102 ◽

2007 ◽

Vol 21 (6) ◽

pp. 719-724 ◽

Cited By ~ 12

Author(s):

Wilma T. Anselmo-Lima ◽

Maria Dolores Seabra Ferreira ◽

Fabiana Cardoso Pereira Valera ◽

Maria Rossato ◽

Valder Rodrigues de Mello ◽

...

Keyword(s):

Maxillary Sinus ◽

Endoscopic Sinus Surgery ◽

Functional Endoscopic Sinus Surgery ◽

Sinus Surgery ◽

Histological Evaluation ◽

Sinus Mucosa

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Effects of Functional Endoscopic Sinus Surgery on Maxillary Sinus Mucosa

Archives of Otolaryngology - Head and Neck Surgery ◽

10.1001/archotol.1997.01900100073010 ◽

1997 ◽

Vol 123 (10) ◽

pp. 1097-1100 ◽

Cited By ~ 20

Author(s):

Y. Guo ◽

Y. Majima ◽

M. Hattori ◽

S. Seki ◽

Y. Sakakura

Keyword(s):

Maxillary Sinus ◽

Endoscopic Sinus Surgery ◽

Functional Endoscopic Sinus Surgery ◽

Sinus Surgery ◽

Sinus Mucosa

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Wound Healing in the Rabbit Paranasal Sinuses after Coblation: Evaluation for use in Endoscopic Sinus Surgery

American Journal of Rhinology and Allergy ◽

10.2500/ajra.2009.23.3326 ◽

2009 ◽

Vol 23 (3) ◽

pp. 360-363 ◽

Cited By ~ 14

Author(s):

Laura H. Swibel Rosenthal ◽

Michael S. Benninger ◽

Chad H. Stone ◽

Mark A. Zacharek

Keyword(s):

Wound Healing ◽

Maxillary Sinus ◽

Paranasal Sinuses ◽

Endoscopic Sinus Surgery ◽

Respiratory Epithelium ◽

Sinus Surgery ◽

Partial Replacement ◽

Pattern Of Injury ◽

Bipolar Radiofrequency ◽

Sinus Mucosa

Background Bipolar radiofrequency can be used surgically to excise and cauterize tissue simultaneously. It has potential for use in endoscopic sinus surgery (ESS). This study was performed to determine the extent and pattern of injury in the paranasal sinuses with bipolar radiofrequency and evaluate wound healing. Methods Eight rabbits underwent Coblation of maxillary sinus mucosa with biopsy immediately, on postoperative day (POD) 3, 7, 14, or 29. Maxillary mucosa was exposed through the nasal dorsum, and a Coblator PROciseXP wand used on a power setting of 7 for 2 seconds. Three of the rabbits also had Coblation of ethmoid mucosa over the lamina papyracea, after extending the maxillary ostomy, with biopsy immediately. Results Coblation resulted in immediate loss of surface respiratory epithelium and thermal-type injury to the underlying seromucinous glands. On POD 3, the site showed reepithelialization with squamous metaplastic epithelium. The seromucinous glands underwent coagulative necrosis. At POD 7, there was partial replacement of overlying epithelium by respiratory epithelium. The underlying seromucinous glands were lost and replaced by fibroblastic proliferation, with less fibrosis than the mechanically created ostomy site. The underlying bone had reactive, regenerative changes. On PODs 14 and 29, there was further regeneration of respiratory epithelium. Fibrosis was mild. Coblation resulted in gross violation of the bony wall in one maxillary sinus. There were no histological changes in the orbit. Conclusion Rabbit paranasal sinus mucosa heals appropriately after Coblation injury.

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