scholarly journals Ethnobotanical study of medicinal plants used against sickle cell anaemia in the eastern part of the Côte d’Ivoire

2020 ◽  
Vol 45 (1) ◽  
pp. 7839-7852
Author(s):  
Akakpo-Akue J ◽  
Kplé T.K.M ◽  
Coulibaly Kiyinlma ◽  
AHON Gnamien Marcel ◽  
Fofié Yvette ◽  
...  

An ethnobotanical survey was conducted to record the various plant families, species, and plant parts used to manage sickle cell disease in the Indenié-Djouablin region eastern Côte d’Ivoire. Nine traditional healers aged 36 to 67 years old were selected in six different villages according to their reputation in knowledge of traditional medicine, their availability and their willingness to share information. A total of 26 species of plants belonging to 20 families were reported to have antisickling activity. Eleven (11) different medication recipes were composed from these 26 species of plants ((Afromonum melegueta (Roscoe) K. Schum., Xylopia aethiopica) mainly). The main plant parts used were stem bark (38%) followed by fruit (18%) and seeds (18%). The majority of the main plants recorded (84.61 %) were wild. From the recorded plants, 65.38 % were trees and 23.07 % shrubs. Most remedies (82%) were made up by decoction and were employed orally (54 %) or by enema (32 %). The potential anti-sickling activity of the plant species recorded during this study could be the effect of alkaloids, polyphenols, quinones and terpenoids compounds found during the phytochemical screening of the 26 plants species.

Author(s):  
Koffi Akissi Jeanne ◽  
Tano Konan Dominique ◽  
Kangah Orphée Michelle Alerte ◽  
Rasmane Na Ahou Kaddy ◽  
Ehoulé Kroa ◽  
...  

Mosquitoes have developed resistance, hence the need for anti-malarial medicines. This resistance calls for therapeutic an interest to therapeutic alternatives, including the medicinal plants. An ethnopharmacological survey was conducted amongst 15 Traditional Healers, recommended by the National Program for the Promotion of Traditional Medicine using semi-structured interviews in the city of Bouna. The ethnobotanical survey conducted in 2019 has enabled the identification of 32 plant species belonging to 30 genera and grouped into 19 families. The most represented families were Fabaceae (5 species) Anacardiaceae (4 species), Annonaceae (3 species), Rubiaceae, Zingiberaceae, Asteraceae, and Combretaceae with 2 species each. The species were mostly trees (63.63%). Leaves were the most frequently used parts of the plants (44.4%). The results of our investigations show that the most used mode is the decoction (42.22%). The oral route (60%) is the most used mode of administration. These species complete the non-exhaustive list of medicinal plants that the populations of Cote d'Ivoire use. It was found out that, people in this area commonly use medicinal plants with trust they have built on the curative outcome witnessed. However, this creates a further work to test for the antiplasmodial activity and to develop of Traditional Improved Medicines (MTAs).


Author(s):  
Rasmane Na Ahou Kaddy ◽  
Coulibaly Kalpy Julien ◽  
Kandé Brahima ◽  
Kouamé Kouassi Bernadin ◽  
Djedjagne Marhe Ursule Desirée ◽  
...  

Aims: The present study relates to the hygienic status of medicinal plants sold on markets of the district of Abidjan. This paper focused on Sarcocephalus latifolius used to treat various diseases such as Malaria. Place and Duration of Study: The ethnobotanical survey was conducted during November 2017, on the Siaka Koné market in Abobo. The microbiology study was carried out at “InstitutPasteur de Côte d’Ivoire”. Methodology: A semi-structured interview was used during the survey. Germs were isolated and microbial load counted from aqueous extracts (maceration) of collected samples of stem bark using standard bacteriology methods. Investigations were also made on control sample collected in the Savannah at Lamto reserve (Toumodi). Results: 86% of the plants sold on this market are not well maintained. In fact, 53% of plant organs are stored outdoors on pieces of brick exposed to dust, air humidity and car exhaust. While 20% are under black tarpaulins or stored in dilapidated stores away from light and 13% in bags in open air. To confirm our survey, Sarcocepha luslatifolius was selected from the highest frequency of citations for performing microbiological tests. The number of total coliforms ranged from 1.3×103 to 9.2×107 CFU/g plant, the mean value of total coliforms was 4.7×105 CFU/g, that of mesophilic aerobic germs from 8.1×103 to 5.1×105 CFU/g of plants, the average value of mesophilic aerobic germs was 1.2×105 CFU/g. The presence of Streptococcus, Pseudomonas and Escherichia coli was observed respectively on 93.33%, 16.67% and 3.33% of the samples collected. Conclusion: Medicinal plants sold and stored under current market conditions are potentially dangerous to health.


2018 ◽  
Vol 14 (33) ◽  
pp. 173
Author(s):  
Adou Lydie Marie Dominique ◽  
Zaouri Bi Gala Jean-Marc ◽  
Bene Kouadio ◽  
Zirihi Guédé Noël

An ethnobotanical study with phytochemical screening of some Pteridophytes was carried out in the classified forest of Yapo-Abbé in the south of Côte d'Ivoire, in the Agboville Department, precisely in the subprefecture of Azaguié. The objective of this study was to show the different uses of the Pteridophytes of this forest. The approach method is an ethnobotanical survey carried out among the populations of the study area. This survey consisted in drafting a questionnaire beforehand to apprehend the multiple uses of Pteridophytes among the surrounding population and to develop a photo album of Pteridophytes to be presented during the interview. The data collection was carried out using the semi-structured interview method and with the help of an interpreter guide. It identified 19 species of Pteridophytes including six (6) species used as medicinal plants. No other use of these taxa was mentioned. The whole plant is the most solicited or 73.33% for the preparation of medicinal recipes. Various methods of preparation such as decoction (33.3%), kneading (33.3%), softening (20%) and use in the fresh state (13.3%) are used for recipes. single species. There are also different modes of administration of phytomedicaments: drink (42.85%), local application (37.71%), mastication (7.14%) and massage (7.14%). The phytochemical sorting performed on the hydroethanolic extracts revealed that the different drugs of these plants contain sterols, polyterpenes, polyphenols, European Scientific Journal November 2018 edition Vol.14, No.33 ISSN: 1857 – 7881 (Print) e - ISSN 1857- 7431 174 flavonoids, catechin tannins, alkaloids and quinones which give them various therapeutic properties.


2020 ◽  
Vol 4 (1) ◽  
pp. 039-050
Author(s):  
Amon Anoh Denis-Esdras ◽  
Ahoulou Assoum Stanislas ◽  
Achah Jacques Auguste Alfred Bognan ◽  
Sebe Fiba Doriane ◽  
Soro Dodiomon ◽  
...  

Loranthaceae are hemiparasitic vascular plants that develop on other woody species. They are used in traditional medicine to treat various pathologies. The present study is a contribution to the knowledge of the medicinal potential of Loranthaceae used in care by Agni Sanwi of Aboisso and Maferé, in the South-East of Côte d'Ivoire. Ethnobotanical surveys were conducted with 50 herbalists and 17 traditional healers using semi-structured interviews. Three (3) species (Globimetula braunii, Phragmanthera capitata and Tapinanthus bangwensis) divided into 3 genera used to treat 35 diseases were identified. They have been cited in the formulation of several remedies. Malaria, typhoid fever, diarrhea and fontanelle were the most commonly reported conditions. Leaves and leafy twigs are the main organs used. The decoction has been predominant in the acquisition of remedies. The drink was the most cited as a method of administering treatments. The Frequency of Citations (FC) of the Loranthaceae employed in the care and medicinal Informant Agreement Ratio (med.IARs) of the respondents were determined. T. bangwensis had the highest FC (95.52%) and med.IARs (0.73). The therapeutic potentials of Loranthaceae have been highlighted and deserve to be popularized through complementary phytochemical investigations.


2021 ◽  
Vol 9 (1) ◽  
pp. 1
Author(s):  
Adou Adjoumanvoule Honoré ◽  
Kabore Saydou ◽  
Dassé Sery Romuald ◽  
Yeboah Opong Richard ◽  
Goran-Kouacou Amah Patricia ◽  
...  

Author(s):  
Antoinette Régina Ohouo Don ◽  
Pascal Amédée Ahi ◽  
Kouakou Martin Dje

The ethnobotanical study carried out on the fruits of chilli (Capsicum annuum L.), type "Ahalimancou" in the localities of Aniassué, Affalikro, Sankadiokro and the town of Abengourou located in the east of the Côte d’Ivoire had for main objective to assess the levels of knowledge, the mode of use of this pepper by the local populations, as well as the phytochemical analysis of said chilli. Discussion groups and semi-structured individual interviews were carried out in 4 localities to collect information from 650 inhabitants, including 511 women and 139 men. The results showed that the variables gender, age group, ethnicity and level of education significantly influence (p≤0.05) the levels of knowledge and the mode of use, except the independence between the locality, the level of knowledge and mode of use. In addition, women know more about this type of pepper (80.82%) and use it much more in food (99.41%), as well as in the treatment of diseases (95.69%). People aged 60 and over have higher use levels (81.30%) in therapeutic use. The study also revealed that the Agni ethnic group is distinguished from other ethnic groups (Baoulé, Malinké, Attié) by a greater level of knowledge and use in pathology. Depending on the level of education, it appears that people without education know better (71.63%) and use this type of pepper more in the treatment of pathologies (85.39%). In addition, the study showed that the fresh form remains the only form used. With the exception of quinones, phytochemical analysis revealed that this type of pepper contains several pharmacological components depending on the stages of ripeness. Orange and red fruits had a higher content of alkaloids, polyphenols, flavonoids. The green and yellow fruits were highly rich in sterols and polyterpenes. Catechetical tannins were only present in green fruits. The data from our study could strengthen clinical research on the nutritional and pharmacological properties of this type of “Ahalimancou” chilli.


2017 ◽  
Vol 13 (3) ◽  
pp. 371 ◽  
Author(s):  
Doga Dabé ◽  
Zirihi Guédé Noël ◽  
Zézé Adolphe

The high cost of fungicides, the international markets standards for agricultural product quality, the environmental issues and consumer health discourage to the application of chemical control. The strategy is therefore to develop alternative solutions, less expensive and addresses environmental concerns. This study was conducted to evaluate the fungicidal potency of Crotalaria retusa L. on Phytophthora sp. and Fusarium solani, two phytopathogenic fungi. This plant was selected after an ethnobotanical study conducted in the sub-prefecture of Lauzoua in Côte d'Ivoire. It is considered to be the most widely used in the treatment of microbial diseases. The phytochemical screening of this legume species was carried out, and showed the presence of saponosides, sterols, tannins, alkaloids, flavonoids, polyphenols, quinones and polyterpenes. The sensitivity of these two phytopathogenic fungi strains was tested in vitro in presence of the aqueous extract of Crotalaria retusa L. by using double dilution method on PDA medium (Potato Dextrose Agar). The minimum inhibitory concentration (MIC) of spawn growth was 1.56 mg/ml for both fungi. The minimum fungicide concentration (CMF) was 6.25 mg/ml for Phytophthora sp and 12.50 mg/ml for Fusarium solani. The presence of chemical compounds in this plant justifies its antifungal activity and its traditional use areas.


Author(s):  
Traore Kassoum ◽  
Fofana Memon

Background: In Côte d'Ivoire, since the advent of the crisis of the HIV and AIDS epidemic, the structural adjustment policy of the 1980s and the end of the policy of total free healthcare for the majority of the population, the strategies within families for health emerged. In order to heal, the therapeutic routes within families are made by symbolic practices based on traditionalism, modernism and the juxtaposition of traditionalism and modernism. Method: A qualitative study made it possible to collect data from semi-structured interviews with seven (07) families in which 22 key people were interviewed and ten (10) sellers of medicines (including 05 street drug sellers called "cheaper" and 05 traditional healers for medicinal plants). Also, a detailed documentary exploitation and a participant observation for a period of eight (8) months structured by an observation grid formalized in a notebook were conducted. These data were analyzed by taking into account endogenous and exogenous knowledge including the symbolic practices of structuring health within families and this community. Result: The study shows that therapeutic dynamics within families are dominated by curative care practices with a juxtaposition of mobilizable care (modern and traditional medicine, self-medication). This domination of the curative on the preventive is intended to anesthetize the health or therapeutic awareness of the patient and his family. In addition, the study found that the pharmaceutical basket is largely structured therapeutic products housed in the tradition model and therapeutic products under the "common sense" (street drug). The consequence of all these health practices within families is the observation of the death of the individual by an easily curable disease. Conclusion: The present study was conducted in the Abbey community, an ethnic group in the southern region of Côte d'Ivoire, an area strongly marked by the colonization. The objective was to understand the social dynamics that structure the therapeutic practices and perceptions for the health care and preservation of the members of this community based on the health results obtained. In analysis, the remoteness of individuals from preventive therapeutic practices advocated by the health authorities is part of the actor strategy that Michel Crozier (1977) discusses, either to circumvent the financial expenses, or to give meaning to an event not judged too unfavorable for them or to reach a socio-cultural order not communicable.


Sickle cell disease is the most popular genetic disease in the world. In Côte d’Ivoire, the SCD prevalence is 12%. As such, SCD is a public health problem. Few studies are really investigating the relative levels of Th1, Th2 and Th17 types in black Africans and in the occurring of alloimmunization. This works attempts to identify the cytokine pattern produced by these patients during the course of the disease as Th1 cytokines, Th2 cytokines and Th17 and the relationship with alloimmunization. Patients and Methods: This is a prospective study followed at the National blood Transfusion Center in Abidjan, Côte d’Ivoire. Cytokines were measured by using Bio Legend’s LEGEND plexTM Human Inflammation Panel assays. We used Grifols DG gel® system to perform the immune hematology tests. Results: We recruit 50 patients with a diagnosis of sickle cell disease (SCD). Of these, only 31 have benefited from the research of irregular agglutinins (62%), comprising 14males (45.16%) and 17 females (54.84 %). The overall alloimmunization prevalence of 16.12%. The prevalence of alloimmunization was significantly greater in males than in females (60%). According to alloimmunization, we note an increased levels of IL-10 in non alloimmunized patients with SCD, when compared with alloimmunized and the levels of IL-4 was higher in alloimmunized patients compared to non alloimmunized. Lower IFN-γ levels were detected in non alloimmunized and alloimmunized SCD patients. Concerning IL-17, there was a small increase in patients without alloantibodies compared to those with. However no significant differences were noted in the 2 groups. Conclusion: The impact of biomarkers in the occurrence of alloimmunization is a constant preoccupation of researchers. Due to lack of financial aspect, small number of patients was enrolled. Even, we cannot draw any definitive conclusion; however our study brings data regarding the functioning of the immune system in SCD giving valuable insight.


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