Updates in the management of Guillain Barre Syndrome

Barré and Strohl in 1916. Although GBS has a good prognosis (5% mortality rate), about 10% of patients experience serious disability one year after the start of neurological onset. Recent research of GBS shows that the process involves a number of subtypes with different immunological mechanism and a spectrum of clinical syndrome of acute inflammatory neuropathy. Antibodies against peripheral nerve gangliosides and their own complements are recognized as an important mechanism of nerve damage in GBS. Pharmacokinetics of intravenous immunoglobulin (IVIg) therapy and other related factors that influence prognosis has been researched. In order to investigate the possible role of complement inhibition in GBS management, new studies will be conducted. The management of GBS should be provided in appropriate hospital units, with specialist teams, intensive care and rehabilitation facilities as essential parts. This article aims to provide updated management of GBS.Citation: Imelda NC, Baktir F, Fidiana, Hidayati HB, Basuki M. Updates in the management of Guillain Barre Syndrome. Anaesth Pain & Intensive Care 2018;22 Suppl 1:S54-S57

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Guillain-Barre syndrome- Rationale for physiotherapy management of the acute severe patient

South African Journal of Physiotherapy ◽

10.4102/sajp.v52i4.620 ◽

1996 ◽

Vol 52 (4) ◽

pp. 85-87 ◽

Cited By ~ 1

Author(s):

Lynn Fearnhead ◽

Vivian U. Fritz

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Supportive Care ◽

Clinical Features ◽

Guillain Barre Syndrome ◽

Critical Importance ◽

Guillain Barré Syndrome ◽

Guillain Barré ◽

Severe Patient

The critical importance of supportive care including physiotherapy to the acute severe Guillain-Barre patient is emphasised in numerous reports in the literature. However, there are no systematic studies of physiotherapy in Guillain-Barre syndrome (GBS). This article examines the aetiology, pathology, clinical features, prognosis and treatment of GBS with reference to the physiotherapists’ management of the acute severe patient treated in an intensive care unit.

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Two success stories in the management of Guillain–Barré syndrome illustrate the challenges of intensive care unit care in Malawi

Tropical Doctor ◽

10.1177/0049475520962757 ◽

2020 ◽

pp. 004947552096275

Author(s):

Lauren Onofrey ◽

Claire Naus ◽

Kiran T Thakur ◽

Clement Kadyaudzu ◽

Meghan Prin

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Early Recognition ◽

Tertiary Hospital ◽

Guillain Barre Syndrome ◽

Intensive Care Unit Care ◽

Low Resource ◽

Success Stories ◽

Guillain Barré Syndrome ◽

Guillain Barré

The management of critical illness is especially challenging in low-resource environments, and early recognition and supportive care are essential, regardless of the ability to employ advanced or invasive therapy. In this report, we discuss two patients with Guillain–Barré syndrome who were managed successfully in the intensive care unit of a tertiary hospital in Malawi. Both patients recovered and were discharged home. The management and outcomes of these patients provide case-based lessons for improving intensive care unit medicine in low-resource contexts.

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Experiences with Guillain-Barré syndrome in a pediatric intensive care unit

Intensive Care Medicine ◽

10.1007/bf00255788 ◽

1987 ◽

Vol 13 (5) ◽

pp. 328-331 ◽

Cited By ~ 17

Author(s):

A. P. Bos ◽

F. G. A. van der Meché ◽

M. Witsenburg ◽

E. van der Voort

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Pediatric Intensive Care Unit ◽

Pediatric Intensive Care ◽

Guillain Barre Syndrome ◽

Guillain Barré Syndrome ◽

Guillain Barré

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Autonomic dysfunction in Guillain-Barré Syndrome: a 13 year experience in pediatric intensive care unit

Jornal de Pediatria ◽

10.2223/jped.579 ◽

1996 ◽

Vol 72 (1) ◽

pp. 20-26 ◽

Cited By ~ 1

Author(s):

João Carlos Batista Santana ◽

Pedro Celiny Ramos Garcia ◽

Paulo Einloft ◽

Délio J. Kipper ◽

Maria Luiza Chiapin ◽

...

Keyword(s):

Intensive Care Unit ◽

Intensive Care ◽

Pediatric Intensive Care Unit ◽

Autonomic Dysfunction ◽

Pediatric Intensive Care ◽

Guillain Barre Syndrome ◽

Guillain Barré Syndrome ◽

Guillain Barré

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Guillain Barre Syndrome pada Kehamilan

Jurnal Ilmiah Kedokteran Wijaya Kusuma ◽

10.30742/jikw.v9i2.702 ◽

2020 ◽

Vol 9 (2) ◽

pp. 256

Author(s):

Hermin Sabaruddin ◽

Pribakti Budinurdjaja ◽

Fakhrurrazy Fakhrurrazy

Keyword(s):

Physical Examination ◽

First Trimester ◽

Clinical Syndrome ◽

Guillain Barre Syndrome ◽

High Morbidity ◽

Autoimmune Reaction ◽

Guillain Barré Syndrome ◽

History Of ◽

Guillain Barré ◽

In Pregnancy

Guillain-Barre Syndrome (GBS) is a clinical syndrome characterized by the presence of the complete flaksid that occurs in acute. GBS associated with autoimmune reaction that affect peripheral nerve, radix, and cranial nerve. The incidence of GBS is 1 – 2 per 100,000 people/year. The incident was followed by increased age and the increasing population of obstetrics. GBS in pregnancy ranged from 13% in the first trimester, 47% in the second trimester, and 40% in the third trimester. In this case report reported Mrs. M 27 years old with a diagnosis of G2P1A0 h. 39-40 weeks + insimanation + living single fetal Presentation Head + Inpartu kala II + GBS + Failed + Vacuum Severily Underweight (BMI = 17) + TBJ 3000 Gr. Diagnosis of GBS are enforced based on anamnesis, physical examination and complementary examinations. From a previous illness history found anamnesis the weakness of limbs beginning in 2016. A history of the use of breathing apparatus and admitted tot the ICU in the first pregnancy. Mrs. M had a history of infections before being diagnosed with GBS. On this second pregnancy patients cannot move lower extremity but upper extermity is still functioning. Physical examination result of mothers and babies in the normal range even though found in conditions of severily BMI underweight. The patient finally decided to SC (section caesaria) and applied the IUD intracaesarean GBS in pregnancy is a coincidental. GBS is rarely aggravate pregnancy, but if not quickly identified and handled can enhance the high morbidity in both mother and fetus. In acute attacks (AIDP) in pregnant women with GBS increase stress on the mother or the fetus. The stress that occurs can also stimulate the immune system to produce prostaglandins, resulting in premature birth. Patients can give birth when the gestational age is still 7 months. It was different in the second pregnancy in this case where the patient was diagnosed with chronic inflammatory demyelinating polyradiculopathy (CIDP) so that GBS did not affect the mother and the fetus.

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