scholarly journals Complex Regional Pain Syndrome in a Young Boy After Receiving a Diphtheria, Tetanus, and Acellular Pertussis Vaccine

2020 ◽  
pp. 203-206
Author(s):  
Sarang S. Koushik

Background: Complex regional pain syndrome (CRPS) is a clinically diagnosed multifaceted condition comprising of physical complaints often with a psychological component. CRPS can result in devastating chronic pain and disability if not treated early and aggressively. Mostly seen in adults, CRPS is being described more frequently in children. There have been some rare reports of CRPS occurring after vaccine administration. This is a case report of a young boy who developed CRPS after receiving a routine vaccination. Case Presentation: Although CRPS has been reported after rubella and hepatitis B vaccine, this is a case of CRPS after a diphtheria, tetanus, and acellular pertussis vaccine. Delays in diagnosis may cause undue pain, extended lengths of treatment, requirements for more intense therapy, and less likelihood for complete functional restoration. Because there seems to be no common constituent to the vaccines described in this case, the resultant CRPS may be purely due to injection-site trauma. Conclusion: We encourage physicians to be wary of the syndrome and its link to multiple vaccines in order to initiate prompt treatment. Key words: Complex regional pain syndrome (CRPS), reflex sympathetic dystrophy (RSD), children, vaccination, diphtheria, tetanus, acellular pertussis (TDAP)

Author(s):  
Roger M. Atkins

♦ Complex regional pain syndrome (CRPS) is a disabling chronic pain condition of unknown aetiology♦ Traditionally it was thought to be rare; however, prospective studies demonstrate it to be common following both trauma and operative procedures involving the upper and lower limbs♦ The condition is usually self-limiting over a maximum period of 2 years, although minor abnormalities may remain♦ In a minority of cases it does not resolve and is responsible for severe chronic disability♦ Treatment is aimed at functional restoration of limb function supported by pharmacological intervention.


2019 ◽  
Vol 30 (3) ◽  
pp. 211-222
Author(s):  
Paulo Henrique Pires de Aguiar ◽  
Bruno Camporeze ◽  
Caroline Zapelini ◽  
Ricardo Hiroshi Murashita Fujiki ◽  
Jonathan Watanabe Rodriguez ◽  
...  

Background: The Complex Regional Pain Syndrome (CRPS), known as reflex sympathetic dystrophy, Sudeck atrophy, causalgy or posttraumatic pain has been described as an important cause of chronic morbidity, which acknowledge of clinical limits, pathophysiology and implications of pathogenesis is still little elucidated. Therefore a great dissatisfaction for patients and health professionals has been described regarding to the currently available therapeutic methods. Objectives: The goal of this paper is to discuss the current perspectives of physiopathology, diagnosis and treatment in CRPS. Methods: A review of the literature was carried out using the MEDLINE, LILACS, and SciELO databases, with preference to articles in English, Portuguese and Spanish. Results: The diagnosis is predominantly based in clinical evidences of signs and symptoms. Although it has been described in the literature in many studies and guidelines about the treatment of CRPS, there is no consensus of procedure indications. Between the surgical methods, the use of spinal cord stimulation and others neuromodulators approaches has been described associated to significant rates of success in the management of CRPS. Conclusion: According to the literature and authors experience, the successful treatment of CRPS is based in early diagnosis associated to experienced interdisciplinary team aiming the functional restoration and psychological aspect monitoring.


2009 ◽  
Vol 14 (6) ◽  
pp. 1-9
Author(s):  
Robert J. Barth

Abstract Complex regional pain syndrome (CRPS) is a controversial, ambiguous, unreliable, and unvalidated concept that, for these very reasons, has been justifiably ignored in the “AMA Guides Library” that includes the AMAGuides to the Evaluation of Permanent Impairment (AMA Guides), the AMA Guides Newsletter, and other publications in this suite. But because of the surge of CRPS-related medicolegal claims and the mission of the AMA Guides to assist those who adjudicate such claims, a discussion of CRPS is warranted, especially because of what some believe to be confusing recommendations regarding causation. In 1994, the International Association for the Study of Pain (IASP) introduced a newly invented concept, CRPS, to replace the concepts of reflex sympathetic dystrophy (replaced by CRPS I) and causalgia (replaced by CRPS II). An article in the November/December 1997 issue of The Guides Newsletter introduced CRPS and presciently recommended that evaluators avoid the IASP protocol in favor of extensive differential diagnosis based on objective findings. A series of articles in The Guides Newsletter in 2006 extensively discussed the shortcomings of CRPS. The AMA Guides, Sixth Edition, notes that the inherent lack of injury-relatedness for the nonvalidated concept of CRPS creates a dilemma for impairment evaluators. Focusing on impairment evaluation and not on injury-relatedness would greatly simplify use of the AMA Guides.


2016 ◽  
Author(s):  
Roy K. Esaki

Ketamine is an N-methyl-d-aspartate (NMDA) receptor antagonist that has been increasingly used in the management of treatment-resistant chronic pain conditions, particularly representing neuropathic involvement or central sensitization. Complex regional pain syndrome (CRPS) is a prototypical condition often treated with ketamine infusions. Although the analgesic benefits of ketamine as an opioid-sparing adjunct in the preoperative period have been well studied, the use of ketamine to mitigate chronic pain conditions remains largely anecdotal, composed largely of case reports and uncontrolled small studies. The limited evidence and published reports support the use of ketamine infusions as one aspect of a comprehensive, multimodal approach for CRPS. Although ketamine infusions are relatively safe when titrated appropriately, with minimal respiratory depression, side effects include sympathetic activation, unpleasant psychomimetic effects, lower urinary tract symptoms, and hepatic dysfunction. 


2004 ◽  
Vol 23 (1) ◽  
pp. 145-155 ◽  
Author(s):  
Robert D Teasdall ◽  
Beth Paterson Smith ◽  
L.Andrew Koman

Author(s):  
Gavin Clunie ◽  
Nick Wilkinson ◽  
Elena Nikiphorou ◽  
Deepak R. Jadon

The Oxford Handbook of Rheumatology 4th edition, has been extensively updated to thoroughly review aspects of musculoskeletal pain. Pain pathophysiology is reviewed. Chronic pain and fibromyalgia in adults and in children and adolescents is dealt with in detail. The reader is advised to cross reference from this chapter to Chapters 1–3 in the Handbook, where regional musculoskeletal pain conditions are listed and reviewed. In localized pain syndromes, the chapter has an overview of complex regional pain syndrome (CRPS), which is not infrequently encountered in rheumatology and musculoskeletal clinics. Included in detail for this edition, is the assessment and management of pain in children, which is a highly specialized clinical area of medicine and will be of use to the adult rheumatologist and general practitioner as well as paediatric specialists. Readers should cross reference to Chapter 23 on medications, for ‘pain medications’ in the Handbook


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