ROLE OF CD163+ TUMOUR ASSOCIATED MACROPHAGES IN PROGNOSTICATION OF PATIENTS DIAGNOSED OF HODGKIN'S LYMPHOMA: A PROSPECTIVE COHORT STUDY

2021 ◽  
pp. 9-10
Author(s):  
Akshay Sharma ◽  
Anshu Sharma
Keyword(s):  
Cohort Study ◽  
Treatment Response ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Hodgkin’S Lymphoma ◽  
Early Stage ◽  
Univariate Analysis ◽  
Hodgkin's Lymphoma ◽  
End Of Treatment ◽  
Advanced Stages

Hodgkin's lymphoma (HL) constitutes around 30% of all lymphomas . IPS is used for the risk stratication of advanced stage HL but it lack applicability to the early stage cases ..In this prospective cohort study, we aim to conrm the relationship between CD68+TumourAssociated macrophages with treatment response (interim as well as end of treatment) of HL treated with the standard chemotherapy and radiotherapy regimens. A total of 50 patients were recruited over a period of 18 months and the patients were followed up in the hematology clinic and interim treatment responses as well as end of treatment response were assessed. Correlation of the CD163+Tumour Associated Macrophages and the treatment response showed that the Higher Percentages of CD163+Tumour Associated Macrophages were associated with more advanced stages.. Univariate analysis showed that there was no signicant correlation of interim treatment response as well as end of treatment response with CD163+Tumour Associated macrophages levels .

ROLE OF SERUM LDH LEVELS IN PROGNOSTICATION OF PATIENTS DIAGNOSED OF HODGKIN'S LYMPHOMA: A PROSPECTIVE COHORT STUDY

2021 ◽  
pp. 13-15
Author(s):  
Akshay Sharma ◽  
Anshu Sharma
Keyword(s):  
Cohort Study ◽  
Treatment Response ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Hodgkin’S Lymphoma ◽  
Early Stage ◽  
Univariate Analysis ◽  
Hodgkin's Lymphoma ◽  
End Of Treatment ◽  
Advanced Stages

Hodgkin's lymphoma (HL) constitutes around 30% of all lymphomas . IPS is used for the risk stratication of advanced stage HL but it lack applicability to the early stage cases ..In this prospective cohort study, we aim to conrm the relationship between hsCRP levels with treatment response (interim as well as end of treatment) of HL treated with the standard chemotherapy and radiotherapy regimens. A total of 50 patients were recruited over a period of 18 months and the patients were followed up in the hematology clinic and interim treatment responses as well as end of treatment response were assessed. Correlation of the serum LDH levels and the treatment response showed that the low levels of serum LDH level were associated with more advanced stages.. Univariate analysis showed that there was no signicant correlation of interim treatment response as well as end of treatment response with serum LDH levels .

ROLE OF CD68+ TUMOUR ASSOCIATED MACROPHAGES IN PROGNOSTICATION OF PATIENTS DIAGNOSED OF HODGKIN'S LYMPHOMA: A PROSPECTIVE COHORT STUDY

2021 ◽  
pp. 11-12
Author(s):  
Akshay Sharma ◽  
Anshu Sharma
Keyword(s):  
Cohort Study ◽  
Treatment Response ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Hodgkin’S Lymphoma ◽  
Early Stage ◽  
Univariate Analysis ◽  
Hodgkin's Lymphoma ◽  
End Of Treatment ◽  
Advanced Stages

Hodgkin's lymphoma (HL) constitutes around 30% of all lymphomas . IPS is used for the risk stratication of advanced stage HL but it lack applicability to the early stage cases ..In this prospective cohort study, we aim to conrm the relationship between CD68+TumourAssociated macrophages with treatment response (interim as well as end of treatment) of HL treated with the standard chemotherapy and radiotherapy regimens. A total of 50 patients were recruited over a period of 18 months and the patients were followed up in the hematology clinic and interim treatment responses as well as end of treatment response were assessed. Correlation of the CD68+Tumour Associated Macrophages and the treatment response showed that the Higher Percentages of CD68+Tumour Associated Macrophages were associated with more advanced stages.. Univariate analysis showed that there was no signicant correlation of interim treatment response as well as end of treatment response with CD68+Tumour Associated macrophages levels .

scholarly journals ROLE OF HSCRP IN PROGNOSTICATION OF PATIENTS DIAGNOSED OF HODGKIN'S LYMPHOMA: A PROSPECTIVE COHORT STUDY

2020 ◽  
pp. 1-3
Author(s):  
Akshay Sharma ◽  
Abhimanyu Patial
Keyword(s):  
Cohort Study ◽  
Treatment Response ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Hodgkin’S Lymphoma ◽  
Early Stage ◽  
Univariate Analysis ◽  
Hodgkin's Lymphoma ◽  
End Of Treatment ◽  
Advanced Stages

Hodgkin’s lymphoma (HL) constitutes around 30% of all lymphomas(1). IPS is used for the risk stratification of advanced stage HL but it lack applicability to the early stage cases(1)..In this prospective cohort study, we aim to confirm the relationship between hsCRP levels with treatment response (interim as well as end of treatment) of HL treated with the standard chemotherapy and radiotherapy regimens. A total of 50 patients were recruited over a period of 18 months and the patients were followed up in the hematology clinic and interim treatment responses as well as end of treatment response were assessed. Correlation of the hsCRP levels and the treatment response showed that the low levels of hsCRP level were associated with more advanced stages.. Univariate analysis showed that there was no significant correlation of interim treatment response as well as end of treatment response with hsCRP levels.

scholarly journals ROLE OF VITAMIN D3 LEVELS IN PROGNOSTICATION OF PATIENTS DIAGNOSED OF HODGKIN'S LYMPHOMA: A PROSPECTIVE COHORT STUDY

2020 ◽  
pp. 1-3
Author(s):  
Akshay Sharma ◽  
Abhimanyu Patial
Keyword(s):  
Cohort Study ◽  
Treatment Response ◽  
Prospective Cohort Study ◽  
Vitamin D3 ◽  
Prospective Cohort ◽  
Hodgkin’S Lymphoma ◽  
Early Stage ◽  
Univariate Analysis ◽  
Hodgkin's Lymphoma ◽  
End Of Treatment

Hodgkin’s lymphoma (HL) constitutes around 30% of all lymphomas(1). IPS is used for the risk stratification of advanced stage HL but it lack applicability to the early stage cases(1)..In this prospective cohort study, we aim to confirm the relationship between vitaminD3 levels with treatment response (interim as well as end of treatment) of HL treated with the standard chemotherapy and radiotherapy regimens. A total of 50 patients were recruited over a period of 18 months and the patients were followed up in the hematology clinic and interim treatment responses as well as end of treatment response were assessed. Correlation of the vitaminD3 levels and the treatment response showed that the low levels of vitaminD3 were associated with more advanced stages. Univariate analysis showed that there was no significant correlation of interim treatment response as well as end of treatment response with vitamin D3 levels.

Inequality in sentinel lymph node dissection for elderly women with early stage breast cancer: Results from a French prospective cohort study

2012 ◽  
Vol 3 (3) ◽  
pp. 212-219 ◽  
Author(s):  
Camille Cluze ◽  
Frédérique Retornaz ◽  
Dominique Rey ◽  
Mégane Meresse ◽  
Frédérique Rousseau ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cohort Study ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Node Dissection ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Elderly Women ◽  
Early Stage ◽  
Node Dissection

scholarly journals Exploring the Role of Microbiome in Susceptibility, Treatment Response and Outcome among Tuberculosis Patients from Pakistan; Study Protocol for a Prospective Cohort Study (Micro-STOP)

2021 ◽  
Author(s):  
Muhammad Shahzad ◽  
Zia UlHaq ◽  
Simon C Andrews
Keyword(s):  
Immune Response ◽  
Cohort Study ◽  
Treatment Response ◽  
Prospective Cohort Study ◽  
Gut Microbiome ◽  
Prospective Cohort ◽  
Treatment Success ◽  
Anthropometric Measurement ◽  
Microbiome Diversity ◽  
Study Results

Introduction: Tuberculosis (TB) caused by Mycobacterium tuberculosis is a common infectious disease associated with significant morbidity and mortality, especially in low and middle-income countries. Successful treatment of the disease requires prolonged intake (6 to 8 months) of multiple antibiotics with potentially detrimental consequences on the composition and functional potential of the human microbiome. The protocol described in the current study aims to identify microbiome (oral and gut) signatures associated with TB pathogenesis, treatment response and, outcome in humans. Methods and analysis: Four hundred and fifty, newly diagnosed TB patients from three district levels (Peshawar, Mardan, Swat) TB diagnosis and treatment centers will be recruited in this non-interventional, prospective cohort study and will be followed and monitored until treatment completion. Demographic and dietary intake data, anthropometric measurement and blood, stool and salivary rinse samples will be collected at baseline, day 15, month-2 and end of the treatment. Additionally, we will recruit age and sex-matched healthy controls (n=30). Blood sampling will allow monitoring of the immune response during the treatment, while salivary rinse and fecal samples will allow monitoring of dynamic changes in oral and gut microbiome diversity. Within this prospective cohort study, a nested case-control study design will be conducted to assess perturbations in oral and gut microbiome diversity (microbial dysbiosis) and immune response and compare between the patients groups (treatment success vs failure). Ethics and dissemination The study has received ethics approval from the Ethic Board of Khyber Medical University Peshawar, and administrative approval from the Provincial TB Control Program of Khyber Pakhtunkhwa, Pakistan. The study results will be presented at national and international conferences and published in peer-reviewed journals. Trial registration number: NCT04985994; pre-results

scholarly journals Predictors of anxiety in early-stage Parkinson's disease – Results from the first two years of a prospective cohort study

2017 ◽  
Vol 43 ◽  
pp. 49-55 ◽  
Author(s):  
Sonja Rutten ◽  
Peter M. van der Ven ◽  
Daniel Weintraub ◽  
Gregory M. Pontone ◽  
Albert F.G. Leentjens ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Cohort Study ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Early Stage
Sign in / Sign up

Export Citation Format

Share Document