ROLE OF TRIPLE PHASE CONTRAST ENHANCED COMPUTED TOMOGRAPHY IN HEPATIC LESIONS AND THEIR CYTOPATHOLOGICAL CORRELATION

2021 ◽  
pp. 29-33
Author(s):  
Sandeep Kaur ◽  
Chaitanya Tapasvi ◽  
Sarita Nibhoria ◽  
Divya Soin

AIMS: To evaluate the enhancement patterns of hepatic lesions on triple phase contrast enhanced computed tomography and to correlate the CT ndings of hepatic lesions with cytological ndings on ne needle aspiration cytology (FNAC). Settings and Design: This prospective observational study was carried out at Department of Radiodiagnosis, Gobind Singh Medical College and Hospital, Faridkot. The study was approved by the Institutional Ethics Committee. Source of Data: A total of 75 patients who had hepatic lesions on ultrasonography and clinical suspicion of focal hepatic lesions were referred for CECT abdomen. Findings of Triple phase CT for hepatic lesions were correlated with cytopathological ndings. Methods and Material: A Triphasic CECT abdomen was performed on Siemens Somatom Perspective 128 slice scanner in the Department of Radiodiagnosis, Guru Gobind Singh Medical College and Hospital, Faridkot. The entire liver was scanned successively, in arterial, portovenous and delayed phases. A 5mm collimation and 5mm/sec table speed were used. After obtaining a digital scout view, unenhanced scan of the liver was obtained.1.5ml/kg body weight of 300mgI/ml iodinated contrast material was administered by using a pressure injector at a rate of 3.0 mL/s using a pressure injector.USG/CT guided FNAC was done. CT imaging ndings were classied as benign or malignant by correlating them with cytopathological ndings. Results: The present study inferred that Triple phase CECT is a highly sensitive and specic imaging modality for detection and characterization of hepatic lesions with an overall sensitivity and specicity of 100.00 % (95% C.I. 92.45% to 100%) and 92.86% (95% C.I. 76.50% to 99.12%)respectively when correlated with cytopathological ndings. Conclusions: It is inferred from our study that triple phase CECT is highly sensitive and specic imaging modality for detection and characterization of hepatic lesions with wide availability in the present scenario.

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Melisa Lim Seer Yee ◽  
Noraini Abdul Rahim ◽  
Ning Ajleaa Ngah ◽  
Yang Faridah Abdul Aziz ◽  
Sethu Subha

Neck abscesses are difficult to diagnose and treat. Currently, contrast-enhanced computed tomography (CECT) is the imaging modality of choice. The study aims to determine the predictive value of CECT findings in diagnosing neck abscess, causes of neck abscess and the most common neck space involved in the local population. 84 consecutive patients clinically suspected to have neck abscess who underwent CECT and surgical confirmation of pus were included. Demographic and clinical data were recorded. 75 patients were diagnosed as having neck abscess on CECT; out of those 71 patients were found to have pus. Overall CECT findings were found to have a high sensitivity (98.6%) and positive predictive value (PPV) (94.7%) but lower specificity (67.2%) in diagnosing neck abscess. The CECT diagnostic criterion with the highest PPV is the presence of rim irregularity (96%). The most common deep neck space involved is the submandibular compartment, which correlates with the finding that odontogenic cause was the most common identifiable cause of abscess in the study population. Thus, in a patient clinically suspected of having neck abscess, CECT findings of a hypodense mass with rim irregularity are helpful in confirming the diagnosis and guiding clinical management.


Animals ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 11
Author(s):  
Ladislav Stehlík ◽  
Morena Di Tommaso ◽  
Francesca Del Signore ◽  
Michaela Paninárová ◽  
Rossella Terragni ◽  
...  

The liver has a unique vascular supply, and triple-phase contrast-enhanced computed tomography examinations are being performed in order to characterize liver lesions. This study aimed to look for any associations between the attenuation values of liver lesions and their histological classification. The inclusion criteria for this retrospective study were focal or multifocal liver lesions and histological diagnosis. All of the dogs underwent pre-contrast and triple-phase postcontrast computed tomography (CT) examinations with identical timings of the postcontrast series. Thirty-one dogs were included in the study, and various benign and malignant pathologies were identified. The results did not identify any significant differences between the benign and malignant liver lesions, nor between the individual histological diagnoses. Inflammatory lesions were significantly different compared to the normal liver parenchyma, and significant hypoattenuation was found in the portal and delayed venous phases. Hemangiosarcomas were significantly hypoattenuating to the normal liver parenchyma in the pre-contrast and arterial phases, and also to all of the benign lesions in the arterial phase. The other pathologies showed variable attenuation patterns in the different postcontrast phases, and differentiation was not possible. On the basis of this study, triple-phase contrast-enhanced computed tomography cannot differentiate between benign and malignant liver lesions, and biopsy and further histological analysis are necessary.


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