COMBINED IRRADIATION OF PELVIS AND INGUINALNODAL REGIONS USING MODIFIED SEGMENTAL BOOST TECHNIQUE: A PROSPECTIVE STUDY.

2021 ◽  
pp. 71-75
Author(s):  
Sivaraj Kumar. S ◽  
Saravanan. S ◽  
Anbarasi. K
Keyword(s):  
Radiation Treatment ◽  
Target Coverage ◽  
Treatment Techniques ◽  
Dose Volume ◽  
Dosimetric Study ◽  
Dose Homogeneity ◽  
Step And Shoot ◽  
Imrt Planning ◽  
Different Depths ◽  
A Prospective Study

AIM: To describe a novel Modied Segmental Boost Technique (MSBT) for combined irradiation of pelvis and inguinal nodes and to compare the dosimetry of the new method with that of other traditional methods of radiation treatment and IMRT. Total 30 patients who required combined irradiation of pelvis and inguinal regi METHODS AND MATERIALS: ons are included in our study to illustrate details and advantages of MSBT. Conventional photons with enface electrons design was created rst with two opposing parallel elds and four eld box. MSBT plans are generated and patient is treated with this technique to TD 45-50Gy for 5-6 weeks duration. A step-and-shoot inverse IMRT planning was subsequently generated. For dosimetric comparison, these treatment techniques were evaluated by dose-volume histogram (DVH) of PTV and OARs. Dose proles at different depths from each treatment planning were generated for comparison. Comparing the modied segmental boost technique with conventional two oppos RESULTS: ing and four eld box technique, we have found out that the target coverage, dose homogeneity index (DHI) and femoral head sparing is superior in modied segmental boost technique compared to other conventional approaches. And also the patients had better clinical response of both primary and the nodes with minimal skin morbidity when compared with conventionally treated patients data. DHI and target coverage of MSBT was comparable with that of IMRT. CONCLUSION: To cover pelvis and inguinal/femoral nodes, MSBT is technically simple to simulate, plan, and execute. Dosimetric study has demonstrated that it achieves comparable PTV coverage compared with other approaches while at the same time signicantly sparing the surrounding OAR .It also has dose homogeneity comparable with IMRT and can be a nearer alternative for IMRT, in centers which are not having the facility and where the patient load is higher.

Implementation of an in vivo radiochromic film QA procedure

2016 ◽  
Author(s):  
◽  
Jason Stanford
Keyword(s):  
Quality Assurance ◽  
Radiation Treatment ◽  
Radiochromic Film ◽  
In Vivo Dosimetry ◽  
Patient Specific ◽  
Attractive Alternative ◽  
Quality Assurance Procedure ◽  
Imaging Device ◽  
Treatment Techniques

[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Advance treatment techniques, such as IMRT and dynamic conformal arc delivery, are novel radiation treatment procedures at the forefront of accurate and precise radiotherapy. However, the risk of suboptimal treatment resulting in injury is far greater with these techniques due to their complexity. An in vivo quality assurance system is the most appropriate validation of the delivered dose to the patient from these techniques. The intent of this research is to propose an in vivo dosimetry quality assurance procedure using radiochromic film. This research proved that radiochromic in vivo dosimetry is a viable method of detecting spatial patient specific errors in radiotherapy; however, the process is time consuming and not sensitive enough for dosimetric errors associated with weight change. Although time consuming, in vivo radiochromic dosimetry is an attractive alternative for small cancer centers and developing countries without the large startup capital to acquire the electronic portal imaging device necessary for EPID in vivo dosimetry.

Brain-stem tumors in childhood: a prospective randomized trial of irradiation with and without adjuvant CCNU, VCR, and prednisone

1987 ◽  
Vol 66 (2) ◽  
pp. 227-233 ◽  
Author(s):  
R. Derek T. Jenkin ◽  
Carl Boesel ◽  
Inta Ertel ◽  
Audrey Evans ◽  
Robert Hittle ◽  
...  
Keyword(s):  
Adjuvant Chemotherapy ◽  
Brain Stem ◽  
Radiation Treatment ◽  
Risk Of Infection ◽  
Content Type ◽  
Standard Methods ◽  
Increased Risk ◽  
Brain Stem Tumors ◽  
A Prospective Study ◽  
Fine Print

✓ Seventy-four children with a brain-stem tumor diagnosed between 1977 and 1980 were entered into a prospective study in which exploration and assessment for resection were optional, radiation treatment using standard methods was required, and randomization occurred with regard to the use of adjuvant chemotherapy (l-(2-chloroethyl)-l-nitrosourea, vincristine, and prednisone) or no further treatment. The overall 5-year survival rate was 20% and was not improved by the adjuvant chemotherapy program. An increased risk of infection was associated with the adjuvant therapy.

scholarly journals Incidental Dose to Pelvic Nodal Regions in Prostate-Only Radiotherapy

2016 ◽  
Vol 16 (2) ◽  
pp. 211-217 ◽  
Author(s):  
Vedang Murthy ◽  
Shirley Lewis ◽  
Mayur Sawant ◽  
Siji N. Paul ◽  
Umesh Mahantshetty ◽  
...  
Keyword(s):  
Intensity Modulated Radiotherapy ◽  
Conventional Radiotherapy ◽  
Prostate Radiotherapy ◽  
3 Dimensional ◽  
Intensity Modulated ◽  
Treatment Techniques ◽  
Dose Volume ◽  
Internal Iliac ◽  
The Mean ◽  
Conformal Treatment

Objectives: Pelvic lymph nodal regions receive an incidental dose from conformal treatment of the prostate. This study was conducted to investigate the doses received by the different pelvic nodal regions with varying techniques used for prostate radiotherapy. Methods and Materials: Twenty patients of high-risk node-negative prostate cancer treated with intensity-modulated radiotherapy to the prostate alone were studied. Replanning was done for intensity-modulated radiotherapy, 3-dimensional conformal treatment, and 2-dimensional conventional radiotherapy with additional delineation of the pelvic nodal regions, namely, common iliac (upper and lower), presacral, internal iliac, obturator, and external iliac. Dose–volume parameters such as Dmean, D100%, D66%, D33%, V40, and V50 to each of the nodal regions were estimated for all patients. Results: The obturator nodes received the highest dose among all nodal regions. The mean dose received by obturator nodal region was 44, 29, and 22 Gy from 2-dimensional conventional radiotherapy, 3-dimensional conformal treatment, and intensity-modulated radiotherapy, respectively. The mean dose was significantly higher when compared between 2-dimensional conventional radiotherapy and 3-dimensional conformal treatment ( P < .001), 2-dimensional conventional radiotherapy and intensity-modulated radiotherapy ( P < .001), and 3-dimensional conformal treatment and intensity-modulated radiotherapy ( P < .001). The D33% of the obturator region was 64, 39, and 37 Gy from 2-dimensional conventional radiotherapy, 3-dimensional conformal treatment, and intensity-modulated radiotherapy, respectively. The dose received by all other pelvic nodal regions was low and not clinically relevant. Conclusion: The incidental dose received by obturator regions is significant especially with 2-dimensional conventional radiotherapy and 3-dimensional conformal treatment techniques as used in the trials studying elective pelvic nodal irradiation. However, with intensity-modulated radiotherapy, this dose is lower, making elective pelvic irradiation more relevant. Advances in Knowledge: This study highlights that incidental dose received by obturator regions is significant especially with 2-dimensional conventional radiotherapy and 3-dimensional conformal treatment techniques.

Correlation of 2D parameters to lung and heart dose-volume in radiation treatment of breast cancer

2012 ◽  
Vol 52 (1) ◽  
pp. 178-183 ◽  
Author(s):  
Indra J. Das ◽  
Janna Z. Andrews ◽  
Minsong Cao ◽  
Peter A. S. Johnstone
Keyword(s):  
Breast Cancer ◽  
Radiation Treatment ◽  
Heart Dose ◽  
Dose Volume

scholarly journals Intensity-Modulated Radiation Therapy Optimization for Acceptable and Remaining-One Unacceptable Dose-Volume and Mean-Dose Constraint Planning

2020 ◽  
Vol 2020 ◽  
pp. 1-14
Author(s):  
Ryosei Nakada ◽  
Omar M. Abou Al-Ola ◽  
Tetsuya Yoshinaga
Keyword(s):  
Radiation Therapy ◽  
Planning Process ◽  
Intensity Modulated Radiation Therapy ◽  
Optimal Solution ◽  
Intensity Modulated ◽  
Novel Approach ◽  
Dose Volume ◽  
Dose Constraint ◽  
Imrt Planning ◽  
Dose Constraints

We give a novel approach for obtaining an intensity-modulated radiation therapy (IMRT) optimization solution based on the idea of continuous dynamical methods. The proposed method, which is an iterative algorithm derived from the discretization of a continuous-time dynamical system, can handle not only dose-volume but also mean-dose constraints directly in IMRT treatment planning. A theoretical proof for the convergence to an equilibrium corresponding to the desired IMRT planning is given by using the Lyapunov stability theorem. By introducing the concept of “acceptable,” which means the existence of a nonempty set of beam weights satisfying the given dose-volume and mean-dose constraints, and by using the proposed method for an acceptable IMRT planning, one can resolve the issue that the objective and evaluation are different in the conventional planning process. Moreover, in the case where the target planning is totally unacceptable and partly acceptable except for one group of dose constraints, we give a procedure that enables us to obtain a nearly optimal solution close to the desired solution for unacceptable planning. The performance of the proposed approach for an acceptable or unacceptable planning is confirmed through numerical experiments simulating a clinical setup.

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