scholarly journals RADIOLOGICAL RESOLUTION IN A SEVERE COVID PATIENT: A FOLLOW-UP STUDY

2020 ◽  
pp. 65-67
Author(s):  
K. Arun Vishnu ◽  
Athul.C. Angaj ◽  
Trinath Dash
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Pulmonary Fibrosis ◽  
Respiratory Distress Syndrome ◽  
Severity Score ◽  
Distress Syndrome ◽  
Viral Pneumonia ◽  
Ct Scans ◽  
Follow Up Study ◽  
Over Time

PULMONARY FIBROSIS IS A FREQUENT COMPLICATION IN PATIENTS WITH VIRAL PNEUMONIA-INDUCED ACUTE RESPIRATORY DISTRESS SYNDROME. HOWEVER, CT SCANS HAVE SHOWN THAT THE SIGNS OF PULMONARY FIBROSIS AFTER VIRAL PNEUMONIA CAN PARTIALLY REGRESS OVER TIME. SO NOW A DAYS, AS A PART OF COVID TREATMENT, FOR PREVENTING FIBROSIS, WE ARE GIVING ANTI FIBROTICS AND STEROIDS. BUT WE DON’T KNOW THE ACTUAL SEQUALE OF LESIONS IN LUNG DUE TO COVID. HERE WE WOULD LIKE TO DISCUSS ABOUT OUR CASE OF SEVERE COVID-19 INFECTION WHO WAS MANAGED WITH ANTI-FIBROTICS, NIV, ANTI-VIRALS, STEROIDS AND PRONE VENTILATION. THIS PARTICULAR PATIENT HAD CT SEVERITY SCORE OF 21/25 WITH B/L GGOs, FIBROTIC BANDS AND CONSOLIDATORY CHANGES. A 1 MONTH FOLLOW-UP CT SCAN SHOWED A REDUCTION IN CT SEVERITY SCORE (15/25) AND GROSS RESOLUTION IN CONSOLIDATORY CHANGES AND GGOs. THE CLINICAL CONDITION SHOWED A SIGNIFICANT IMPROVEMENT.

Bodily pain in survivors of acute respiratory distress syndrome: A 1-year longitudinal follow-up study

2021 ◽  
Vol 144 ◽  
pp. 110418
Author(s):  
Julia M. Probert ◽  
Shihong Lin ◽  
Haijuan Yan ◽  
Jeannie-Marie S. Leoutsakos ◽  
Victor D. Dinglas ◽  
...  
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Bodily Pain ◽  
Follow Up Study

scholarly journals Analysis of the Cellular Composition of Bronchoalveolar Lavage in the Modeling and Treatment of Acute Respiratory Distress Syndrome in Biomodel Mice

Biomeditsina ◽  
2021 ◽  
Vol 17 (3) ◽  
pp. 17-22
Author(s):  
O. V. Alimkina ◽  
A. E. Petrenko ◽  
E. S. Savchenko ◽  
N. S. Ogneva ◽  
L. A. Taboyakova ◽  
...  
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Bronchoalveolar Lavage ◽  
Distress Syndrome ◽  
Simultaneous Increase ◽  
Single Administration ◽  
Cellular Composition ◽  
Over Time

This article investigates changes in the cellular composition of bronchoalveolar lavage over time in the modeling of acute respiratory distress syndrome (ARDS) in mice, followed by a single administration of Leutragine. In intact animals, macrophages predominate in bronchoalveolar lavage, which is the physiological norm. When modeling ARDS, neutrophils increase. A single administration of Leutragine leads to a significant reduction in the number of neutrophils and a simultaneous increase in macrophages in 72 hours, thus bringing the cellular composition of lavage to normal.

scholarly journals Cytological analysis of the lung material of C57BL/6Y mice in the simulation of acute respiratory distress syndrome

Biomeditsina ◽  
2021 ◽  
Vol 17 (3E) ◽  
pp. 17-22
Author(s):  
O. V. Alimkina ◽  
A. E. Petrenko
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Bronchoalveolar Lavage ◽  
Blood Cells ◽  
Distress Syndrome ◽  
White Blood Cells ◽  
Intact Group ◽  
Significant Difference ◽  
Over Time

The work is devoted to the study of changes in the cellular composition of bronchoalveolar lavage over time in the modeling of acute respiratory distress syndrome (ARDS) in mice. ARDS was modeled by administering α-galactosylceramide and a mixture of lipopolysaccharide with a complete Freud’s adjuvant. After euthanasia, bronchoalveolar lavage was taken for analysis. On this basis, changes in the total number of white blood cells, the percentage of neutrophils and macrophages were assessed. It was found that the percentage of neutrophils in the ARDS group shows a statistically significant difference from that in the intact group, starting from 3 hours after modeling ARDS. Further, a statistically significant decrease in macrophages was observed. 

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