MYOMA PLACENTA RELATIONSHIP & PREGNANCY OUTCOME

2021 ◽  
pp. 3-4
Author(s):  
Savita Chandra

During the two years study period, 8557 deliveries took place, of which 114 were pregnancies with myoma giving the incidence as 1.33%. 12 of the 114 pregnancies ended in abortion, i.e.10.5%. The myoma placenta relationship and the obstetric outcome was analyzed in the remaining 102 pregnancies which continued beyond 22 weeks. Of these, 41.2% had complications. Premature rupture of membranes was the commonest complication seen in 22.5%. No case of preeclampsia or antepartum haemorrhage occurred in the 'no contact' category. Amongst the cases where the placenta was either in contact or superimposed on the broid, 85.5% -87.5% developed one or more complication. The myoma placenta relationship was found to be statistically signicant, p value <0.001. 39.3% were caesarean deliveries. Overall 37.25% were low birth weight neonates. There were two stillbirths, both in the superimposed category.

2016 ◽  
Vol 3 (1) ◽  
Author(s):  
Bosede B. Afolabi ◽  
Olusanjo E. Moses ◽  
Oyinlola O. Oduyebo

Abstract Background.  Bacterial vaginosis (BV) is a complex clinical syndrome characterized by alterations in the normal vaginal flora and a malodorous discharge when symptomatic. In pregnancy, BV has been associated with adverse outcomes such as miscarriage, premature rupture of membranes, preterm birth, and low birth weight. This study was conducted to determine the prevalence and associations of BV and pregnancy outcomes among pregnant women in Lagos University Teaching Hospital (LUTH). Methods.  We conducted a prospective observational study with high vaginal swabs obtained from consecutive newly registered antenatal women between 14 and 36 weeks gestation. The women were monitored until delivery, and their pregnancy outcome and demographic data were obtained using an interviewer-administered questionnaire. Results.  Bacterial vaginosis was diagnosed by Nugent score in 64 of 246 women, giving a prevalence rate of 26%. Bacterial vaginosis was significantly associated with preterm delivery (risk ratio [RR], 2.68; 95% confidence interval [CI], 1.44–4.98), low birth weight (RR, 3.20; 95% CI, 1.29–7.94), and premature rupture of membranes (RR, 6.75; 95% CI, 3.11–14.67). The association between BV and miscarriage (&lt;28 weeks gestation) and neonatal admission for various morbidities was not statistically significant. Conclusions.  The prevalence rate of BV among pregnant women in LUTH is high and is significantly associated with adverse pregnancy outcome. Routine screening and treatment of women preconceptually may enable interventions to prevent these adverse outcomes.


2021 ◽  
Vol 97 (2) ◽  
pp. 104-111
Author(s):  
Lisa M Vallely ◽  
Dianne Egli-Gany ◽  
Handan Wand ◽  
William S Pomat ◽  
Caroline S E Homer ◽  
...  

Objective To examine associations between Neisseria gonorrhoeae (NG) infection during pregnancy and the risk of preterm birth, spontaneous abortion, premature rupture of membranes, perinatal mortality, low birth weight and ophthalmia neonatorum. Data sources We searched Medline, EMBASE, the Cochrane Library and Cumulative Index to Nursing and Allied Health Literature for studies published between 1948 and 14 January 2020. Methods Studies were included if they reported testing for NG during pregnancy and compared pregnancy, perinatal and/or neonatal outcomes between women with and without NG. Two reviewers independently assessed papers for inclusion and extracted data. Risk of bias was assessed using established checklists for each study design. Summary ORs with 95% CIs were generated using random effects models for both crude and, where available, adjusted associations. Results We identified 2593 records and included 30 in meta-analyses. Women with NG were more likely to experience preterm birth (OR 1.55, 95% CI 1.21 to 1.99, n=18 studies); premature rupture of membranes (OR 1.41, 95% CI 1.02 to 1.92, n=9); perinatal mortality (OR 2.16, 95% CI 1.35 to 3.46, n=9); low birth weight (OR 1.66, 95% CI 1.12 to 2.48, n=8) and ophthalmia neonatorum (OR 4.21, 95% CI 1.36 to 13.04, n=6). Summary adjusted ORs were, for preterm birth 1.90 (95% CI 1.14 to 3.19, n=5) and for low birth weight 1.48 (95% CI 0.79 to 2.77, n=4). In studies with a multivariable analysis, age was the variable most commonly adjusted for. NG was more strongly associated with preterm birth in low-income and middle-income countries (OR 2.21, 95% CI 1.40 to 3.48, n=7) than in high-income countries (OR 1.38, 95% CI 1.04 to 1.83, n=11). Conclusions NG is associated with a number of adverse pregnancy and newborn outcomes. Further research should be done to determine the role of NG in different perinatal mortality outcomes because interventions that reduce mortality will have the greatest impact on reducing the burden of disease in low-income and middle-income countries. PROSPERO registration number CRD42016050962.


2021 ◽  
Vol 9 ◽  
Author(s):  
Kristina N. Adachi ◽  
Karin Nielsen-Saines ◽  
Jeffrey D. Klausner

Chlamydial trachomatis infection has been associated with adverse pregnancy and neonatal outcomes such as premature rupture of membranes, preterm birth, low birth weight, conjunctivitis, and pneumonia in infants. This review evaluates existing literature to determine potential benefits of antenatal screening and treatment of C. trachomatis in preventing adverse outcomes. A literature search revealed 1824 studies with 156 full-text articles reviewed. Fifteen studies were selected after fulfilling inclusion criteria. Eight studies focused on chlamydial screening and treatment to prevent adverse pregnancy outcomes such as premature rupture of membranes, preterm birth, low birth weight, growth restriction leading to small for gestational age infants, and neonatal death. Seven studies focused on the effects of chlamydial screening and treatment on adverse infant outcomes such as chlamydial infection including positive mucosal cultures, pneumonia, and conjunctivitis. Given the heterogeneity of those studies, this focused review was exclusively qualitative in nature. When viewed collectively, 13 of 15 studies provided some degree of support that antenatal chlamydial screening and treatment interventions may lead to decreased adverse pregnancy and infant outcomes. However, notable limitations of these individual studies also highlight the need for further, updated research in this area, particularly from low and middle-income settings.


Author(s):  
Pratibha Singh ◽  
Vibha Rani Pipal ◽  
Dharmendra Kumar Pipal ◽  
Navdeep Kaur Ghuman ◽  
Garima Yadav ◽  
...  

Background: The aim of this study was to compare the outcomes of pregnancies complicated by isolated oligohydramnios with the low risk pregnancies with normal amniotic fluid volume.Methods: The present study is a retrospective cohort study of singleton pregnancies diagnosed with Isolated oligohydramnios (AFI≤5) in their third trimester (N=35). Pregnancy outcome was compared with a matched control group of low risk pregnancies with amniotic fluid volume >5 (N=30).Results: The overall incidence of Isolated oligohydramnios was 0.7-0.8%. In oligohydramnios group, significant association were found in null-parity (60% vs 23.33%, p-value<0.005), Fetal growth retardation (25.71% vs 0% p-value<0.02), preterm delivery (22.85% vs 3.33%, p-value 0.025), rate of Induction of labor (40% vs 10%) and cesarean rate for non-reassuring fetal heart rate (20% vs 3.33%, p-value<0.001). Likewise, the incidence of low birth weight was (54.28% vs 13.33%, p-value<0.001) and NICU admissions was (20% vs 0%, p-value<0.01), but there was no difference in Apgar score finding. NICU stay was of short duration and all babies discharged in stable condition, there were no stillbirth or early neonatal death in both groups.Conclusions: Isolated oligohydramnios has an adverse influence on pregnancy and neonatal outcome in the form of FGR, preterm delivery, increased rate of Induction and cesarean section. Despite the high incidence of low birth weight and NICU admissions, the overall early neonatal outcome was similar to the other low risk pregnancies.


PEDIATRICS ◽  
1994 ◽  
Vol 93 (6) ◽  
pp. A48-A48

...over 90 percent of the excess risk of very low birth weight among black infants was related to an increased risk among their mothers (risk ratio, 2.5 to 3.5) of chorioamnionitis or premature rupture of membranes (accounting for 38 percent of the excess), hypertensive disorder (12 percent), hemorrhage (10 percent), idiopathic preterm labor (21 percent), or a combination of these maternal conditions (14 percent). It is striking that the same conditions were related to similar percentages of the cases of very low birth weight among white infants. This finding deserves greater emphasis, since it suggests that effective prevention or treatment of any of these conditions in black women would be likely to improve outcomes overall.


2011 ◽  
Vol 9 (2) ◽  
pp. 103-114
Author(s):  
Ditya Yankusuma Setiani

Latar Belakang : Angka Kematian Bayi (AKB) merupakan indikator yang penting untuk mencerminkan keadaan derajat kesehatan di suatu masyarakat. Salah satu kejadian intrapartum yang memiliki kontribusi besar dalam kematian bayi baru lahir adalah asfiksia neonatorum. Asfiksia neonatorum adalah suatu kondisi yang terjadi ketika bayi tidak mendapatkan cukup oksigen selama proses kelahiran. Pengendalian faktor penyebab asfiksia neonatorum sangat penting dalam upaya menurunkan prevalensi terjadinya asfiksia neonatorum. Oleh karena itu perlu dilakukan studi literatur terkait faktor penyebab terjadinya asfiksia neonatorum. Tujuan Penelitian : Mengetahui faktor penyebab terjadinya asfiksia neonatorum. Metode Penelitian : Desain penelitian adalah literatur review. Populasi penelitian ini adalah seluruh artikel hasil penelitian tentang faktor penyebab terjadinya asfiksia neonatorum. Hasil : Hasil literatur review dari lima artikel menunjukkan bahwa faktor penyebab asfiksia neonatorum terdiri dari cairan ketuban dengan pewarnaan meconium, BBLR (Berat Badan Lahir Rendah), persalinan lama, operasi Caesar, ketuban pecah dini, ibu primipara, persalinan rumit, cairan ketuban yang bernoda darah, ibu berumur ? 35 tahun, primigravida, tali pusat ketat, gawat janin intrapartum, malpresentasi janin, dilahirkan melalui rute vagina dengan bantuan vakum, dilahirkan pada malam hari dan dilahirkan dengan bantuan dokter magang sendiri. Kesimpulan : berdasarkan review dari literatur ini dapat disimpulkan bahwa cairan ketuban bernoda meconium, BBLR, persalinan lama dan ketuban pecah dini merupakan faktor penyebab asfiksia neonatorum yang memiliki pengaruh lebih besar.   Kata Kunci : Asfiksia Neonatorum, Faktor Penyebab   REVIEW LITERATURE: FACTORS CAUSING THE OCCURRENCE OF ASPHYXIA NEONATORUM   Ditya Yankusuma Setiani, Lilik Sriwiyati   ABSTRACT Background : Infant Mortality Rate (IMR) is an important indicator to reflect the state of health status in a society. One of the intrapartum events that has a large contribution to the death of newborns is neonatal asphyxia. Asphyxia neonatorum is a condition that occurs when the baby does not get enough oxygen during the birth process. Therefore, controlling the factors that cause neonatal disease is very important in aneffort to reduce the prevalence of neonatal asphyxia. Objectives : To determine the factors causing the incidence of neonatal asphyxia. Methode : The research design of this scientific paper is a literature review. The population of this study were all journals of research results on the factors causing the occurrence of asphyxia neonatorum. Results : The results of the literature review from the 5 journals show the causes of neonatal asphyxia consisting of meconium stained amniotic fluid, low birth weight (LBW), prolonged labor, caesarean section, premature rupture of membranes, primiparous mothers, complicated labor, fluids. Blood stained amniotic fluid, mother ? 35 years old, primigravida, tight umbilical cord, intrapartum fetal distress, fetal malpresentation, via vaginal route with vacuum assistance, assistance at night and assisting with the help of the interns themselves. Conclusion : This study can show that meconium stained amniotic fluid, low birth weight, prolonged labor and premature rupture of membranes are factors causing neonatal asphyxia which have a greater effect.   Keywords: Asphyxia Neonatorum, Causative Factor


2018 ◽  
Vol 23 (4) ◽  
pp. 531-535
Author(s):  
Abida Sajid ◽  
Aqsam Sajid

Pregnancy and childbirth is an event celebrated worldwide. During pregnancy physiological changes and increasing demand causes fall in hemoglobin level leading to anemia and adverse pregnancy outcome especially in young girls. Anemia is a major public health problem. Around 58.27 million women worldwide are anemic during pregnancy 95% of whom live in countries that are developing. To know the frequency of anemia, and obstetric outcome in terms of preterm delivery, low birth weight and rate of caesarean section in young Primigravida. It was a cross sectional study, conducted in the department of Gynae & Obstetric unit 5 King Edward Medical University Lahore during a period of one year from May2013 April 2014. All primigravida young 15-24years with anemia enrolled for the study. Anemia is defined as hemoglobin< 10.5g/dl (WHO Criteria), Iron deficiency Anemia is defined as serum ferritin level less than 12 micro gram per ml and on Red Blood Cell indices, i.e. decrease in MCV, MCH and MCHC, and Microcytic Hypochromic cells in Peripheral Smear. Megaloblastic anemia was labeled when Macrocytic Hypochromic cells seen. Obstetric outcome in terms of Preterm delivery defined as delivery at <37 weeks of gestation (36 +6 weeks) and birth weight <2500g mand a need for operative delivery. Patients fulfilling the selection criteria as per operational definition were included in the study after taking informed consent using non probability consecutive sampling technique. Data was collected on a pre-designed questionnaire. A total of 3855 deliveries during study period in which 1318 were primigravida. Mean age in study group was 15 to 24 years. We observed mild anemia in 46% of woman, moderate anemia in 41% and severe anemia in 13% in young primigravida. Preterm delivery was noted in 25% of the females and low birth weight babies were noted by 33% in teenage and young primigravida. Statistically significant relationship was found between maternal age, education and socio economic status. Anemia in pregnancy nowadays is still a common problem in adolescent and young primigravida and associated with adverse pregnancy outcome. Prompt measure should be taken by the stake holders at local and national level to prevent and treat this problem in order to reduce morbidity and mortality associated with it.


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